Adam S. Himebauch
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View article: Association of preoperative Circulating biomarkers with echocardiographic measures of right ventricular strain five years after tetralogy of fallot repair
Association of preoperative Circulating biomarkers with echocardiographic measures of right ventricular strain five years after tetralogy of fallot repair Open
Purpose We analyzed right ventricular (RV) function using echocardiography after tetralogy of Fallot (TOF) repair to investigate the association between preoperative circulating biomarkers and RV strain five years after repair. We hypothes…
View article: Early exposure to hemodynamic point-of-care ultrasound during pediatric septic shock resuscitation is associated with decreased fluid overload
Early exposure to hemodynamic point-of-care ultrasound during pediatric septic shock resuscitation is associated with decreased fluid overload Open
Objective Fluid overload (FO) after pediatric septic shock resuscitation increases the risk of secondary organ failure and long-term morbidity. We hypothesized that early hemodynamic point-of-care ultrasound (hPOCUS) use in pediatric septi…
View article: Endobronchial valves for severe air leak in critically ill children with necrotizing pneumonia requiring extracorporeal membrane oxygenation
Endobronchial valves for severe air leak in critically ill children with necrotizing pneumonia requiring extracorporeal membrane oxygenation Open
Introduction Air leak is a common complication of necrotizing pneumonia in critically ill children. Severe air leaks impact effective oxygenation and ventilation, oftentimes necessitating multiple thoracostomy tubes and extracorporeal supp…
View article: Right Atrial Dysfunction Is Prevalent in Pediatric Acute Respiratory Distress Syndrome and Reflects Pulmonary Hypertension and Right Ventricular Dysfunction
Right Atrial Dysfunction Is Prevalent in Pediatric Acute Respiratory Distress Syndrome and Reflects Pulmonary Hypertension and Right Ventricular Dysfunction Open
IMPORTANCE: Right atrial (RA) dysfunction is associated with worse outcomes in some populations with pulmonary hypertension or respiratory failure but the prevalence and correlates of RA dysfunction in pediatric acute respiratory distress …
View article: Priorities for Clinical Research in Pediatric Extracorporeal Membrane Oxygenation Anticoagulation From the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference
Priorities for Clinical Research in Pediatric Extracorporeal Membrane Oxygenation Anticoagulation From the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference Open
OBJECTIVES: To identify and prioritize research questions for anticoagulation and hemostasis management of neonates and children supported with extracorporeal membrane oxygenation (ECMO) from the Pediatric ECMO Anticoagulation Collaborativ…
View article: The Influence of the Extracorporeal Membrane Oxygenation Circuit and Components on Anticoagulation Management: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference
The Influence of the Extracorporeal Membrane Oxygenation Circuit and Components on Anticoagulation Management: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference Open
OBJECTIVES: To derive systematic-review informed, modified Delphi consensus regarding the influence of extracorporeal membrane oxygenation (ECMO) circuit components on anticoagulation practices for pediatric ECMO for the Pediatric ECMO Ant…
View article: Executive Summary: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE (PEACE) Consensus Conference*
Executive Summary: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE (PEACE) Consensus Conference* Open
OBJECTIVES: To present recommendations and consensus statements with supporting literature for the clinical management of neonates and children supported with extracorporeal membrane oxygenation (ECMO) from the Pediatric ECMO Anticoagulati…
View article: Ultrasound in Cardiopulmonary Arrest and Resuscitation
Ultrasound in Cardiopulmonary Arrest and Resuscitation Open
Objectives Information obtained from point-of-care ultrasound during cardiopulmonary arrest and resuscitation (POCUS-CA) can be used to identify underlying pathophysiology and provide life-sustaining interventions. However, integration of …
View article: Ultrasound assessment of diaphragm thickness, contractility, and strain in healthy pediatric patients
Ultrasound assessment of diaphragm thickness, contractility, and strain in healthy pediatric patients Open
Background Ultrasound‐based diaphragmatic assessments are becoming more common in pediatric acute care, but baseline pediatric diaphragm thickness and contractility values remain unknown. Methods We conducted a prospective, observational s…
View article: Impaired echocardiographic left ventricular global longitudinal strain after pediatric cardiac arrest children is associated with mortality
Impaired echocardiographic left ventricular global longitudinal strain after pediatric cardiac arrest children is associated with mortality Open
View article: Venovenous Extracorporeal Membrane Oxygenation Initiation for Pediatric Acute Respiratory Distress Syndrome With Cardiovascular Instability is Associated With an Immediate and Sustained Decrease in Vasoactive-Inotropic Scores
Venovenous Extracorporeal Membrane Oxygenation Initiation for Pediatric Acute Respiratory Distress Syndrome With Cardiovascular Instability is Associated With an Immediate and Sustained Decrease in Vasoactive-Inotropic Scores Open
OBJECTIVE: To determine the association of venovenous extracorporeal membrane oxygenation (VV-ECMO) initiation with changes in vasoactive-inotropic scores (VISs) in children with pediatric acute respiratory distress syndrome (PARDS) and ca…
View article: Poor functional status at the time of waitlist for pediatric lung transplant is associated with worse pretransplant outcomes
Poor functional status at the time of waitlist for pediatric lung transplant is associated with worse pretransplant outcomes Open
View article: Outcomes and characteristics of cardiac arrest in children with pulmonary hypertension: A secondary analysis of the ICU-RESUS clinical trial
Outcomes and characteristics of cardiac arrest in children with pulmonary hypertension: A secondary analysis of the ICU-RESUS clinical trial Open
View article: Epinephrine dosing strategies during pediatric extracorporeal cardiopulmonary resuscitation reveal novel impacts on survival: A multicenter study utilizing time-stamped epinephrine dosing records
Epinephrine dosing strategies during pediatric extracorporeal cardiopulmonary resuscitation reveal novel impacts on survival: A multicenter study utilizing time-stamped epinephrine dosing records Open
View article: Acute respiratory failure-related excess mortality in pediatric sepsis
Acute respiratory failure-related excess mortality in pediatric sepsis Open
Excess mortality risk imparted by acute respiratory failure in children is unknown. We determined excess mortality risk associated with mechanically ventilated acute respiratory failure in pediatric sepsis. Novel ICD10-based algorithms wer…
View article: Cardiac Point-of-Care Ultrasound in Pediatric Neurocritical Care: A Case Series
Cardiac Point-of-Care Ultrasound in Pediatric Neurocritical Care: A Case Series Open
View article: Primary graft dysfunction grade 3 following pediatric lung transplantation is associated with chronic lung allograft dysfunction
Primary graft dysfunction grade 3 following pediatric lung transplantation is associated with chronic lung allograft dysfunction Open
View article: Alveolar dead space fraction is not associated with early RV systolic dysfunction in pediatric ARDS
Alveolar dead space fraction is not associated with early RV systolic dysfunction in pediatric ARDS Open
Primary Hypothesis We hypothesized that higher alveolar dead space fraction (AVDSf) at pediatric acute respiratory distress syndrome (PARDS) onset would be associated with right ventricular (RV) systolic dysfunction within the first 24 h o…
View article: Simulation-Facilitated Education for Pediatric Critical Care Nurse Practitioners' Airway Management Skills: A 10-Year Experience
Simulation-Facilitated Education for Pediatric Critical Care Nurse Practitioners' Airway Management Skills: A 10-Year Experience Open
This study aimed to describe the process of the development and implementation with report of our 10-year experience with a simulation-facilitated airway management curriculum for pediatric acute care nurse practitioners in a large academi…
View article: Alveolar Dead Space Fraction is Not Associated with Early RV Systolic Dysfunction in Pediatric ARDS
Alveolar Dead Space Fraction is Not Associated with Early RV Systolic Dysfunction in Pediatric ARDS Open
Primary Hypothesis: We hypothesized that higher alveolar dead space fraction (AVDSf) at PARDS onset would be associated with right ventricular (RV) systolic dysfunction within the first 24 hours of PARDS. Study Design and Methods: We perfo…
View article: Risk Factors Associated With Bleeding in Children With Cardiac Disease Receiving Extracorporeal Membrane Oxygenation: A Multi-Center Data Linkage Analysis
Risk Factors Associated With Bleeding in Children With Cardiac Disease Receiving Extracorporeal Membrane Oxygenation: A Multi-Center Data Linkage Analysis Open
Background: Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO) for pediatric cardiac patients. We aimed to identify anticoagulation practices, cardiac diagnoses, and surgical variables associated with bleeding …
View article: Urinary Biomarkers and Attainment of Cefepime Therapeutic Targets in Critically Ill Children
Urinary Biomarkers and Attainment of Cefepime Therapeutic Targets in Critically Ill Children Open
INTRODUCTION The recommended therapeutic target for cefepime (FEP) is the time above MIC ( f T>MIC). The frequency of target attainment and risk factors for sub-therapeutic concentrations in children have not been extensively studied. METH…
View article: The Impact of a Pediatric Continuity Care Intensivist Program on Patient and Parent Outcomes: An Unblinded Randomized Controlled Trial
The Impact of a Pediatric Continuity Care Intensivist Program on Patient and Parent Outcomes: An Unblinded Randomized Controlled Trial Open
Objectives We studied the impact of a standardized continuity care intensivists (CCIs) program on patient and family outcomes for long-stay patients in the pediatric intensive care unit (PICU), also assessing the intervention's acceptabili…
View article: Biomarkers associated with mortality in pediatric patients with cardiac arrest and acute respiratory distress syndrome
Biomarkers associated with mortality in pediatric patients with cardiac arrest and acute respiratory distress syndrome Open
View article: Pulmonary hypertension among children with in-hospital cardiac arrest: A multicenter study
Pulmonary hypertension among children with in-hospital cardiac arrest: A multicenter study Open
View article: A randomized and blinded trial of inhaled nitric oxide in a piglet model of pediatric cardiopulmonary resuscitation
A randomized and blinded trial of inhaled nitric oxide in a piglet model of pediatric cardiopulmonary resuscitation Open
View article: Pediatric Resuscitation Practices During the Coronavirus Disease 2019 Pandemic
Pediatric Resuscitation Practices During the Coronavirus Disease 2019 Pandemic Open
Objectives: While most pediatric coronavirus disease 2019 cases are not life threatening, some children have severe disease requiring emergent resuscitative interventions. Resuscitation events present risks to healthcare provider safety an…
View article: Pediatric cardiopulmonary resuscitation quality during intra-hospital transport
Pediatric cardiopulmonary resuscitation quality during intra-hospital transport Open
View article: Primary Graft Dysfunction Is Associated with Bronchiolitis Obliterans Syndrome Following Pediatric Lung Transplantation
Primary Graft Dysfunction Is Associated with Bronchiolitis Obliterans Syndrome Following Pediatric Lung Transplantation Open
View article: The Association of Pre-Operative Echocardiographic Parameters with Grade 3 Primary Graft Dysfunction Following Pediatric Lung Transplantation
The Association of Pre-Operative Echocardiographic Parameters with Grade 3 Primary Graft Dysfunction Following Pediatric Lung Transplantation Open