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View article: Type 2 Diabetes Mellitus Impairs the Reverse Transendothelial Migration Capacity (rTEM) of Inflammatory CD14+CD16− Monocytes: Novel Mechanism for Enhanced Subendothelial Monocyte Accumulation in Diabetes
Type 2 Diabetes Mellitus Impairs the Reverse Transendothelial Migration Capacity (rTEM) of Inflammatory CD14+CD16− Monocytes: Novel Mechanism for Enhanced Subendothelial Monocyte Accumulation in Diabetes Open
Background: Type 2 diabetes mellitus (DM) is a major cardiovascular risk factor that induces monocyte dysfunction and contributes to their accumulation in atherosclerotic lesions. Monocyte recruitment and accumulation in the tissues contri…
View article: Diagnosis of nascent fibrosis: Interest of marking the relaxed form of fibronectin fibres
Diagnosis of nascent fibrosis: Interest of marking the relaxed form of fibronectin fibres Open
Fibrosis is a pathological and irreversible state of excessively synthesized extracellular matrix fibres induced by abnormal tissue scarring. Effective diagnostic tools for early management of patients with fibrosis are missing. Here, I di…
View article: Guidelines for editors and reviewers of Cell Biology
Guidelines for editors and reviewers of Cell Biology Open
The responsible commitment of life science experts in the evaluation and improvement of research articles is crucial for an efficient scholarly publishing. In Cell Biology, the expert roles and competences are defined in this article. Guid…
View article: Editorial policies of Cell Biology (Marseille, France) journal
Editorial policies of Cell Biology (Marseille, France) journal Open
Cell Biology is a peer-reviewed journal aiming at publishing original articles and reviews communicating new impactful discoveries in life science. Cell Biology is distributed by Rviews Press in Open Access and dedicated to reporting prima…
View article: Guidelines for authors publishing in Cell Biology
Guidelines for authors publishing in Cell Biology Open
Authors need some information to provide that are dependent on the type of article format they want to publish in Cell Biology. Herein, guidelines are given to authors for next submissions to Cell Biology for publication following the edit…
View article: Acetyl-NPKY of integrin-β1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity
Acetyl-NPKY of integrin-β1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity Open
View article: Novel 5-aminopyrazoles endowed with anti-angiogenetic properties: Design, synthesis and biological evaluation
Novel 5-aminopyrazoles endowed with anti-angiogenetic properties: Design, synthesis and biological evaluation Open
View article: New Series of Pyrazoles and Imidazo-Pyrazoles Targeting Different Cancer and Inflammation Pathways
New Series of Pyrazoles and Imidazo-Pyrazoles Targeting Different Cancer and Inflammation Pathways Open
(1) Background: different previously synthesized pyrazoles and imidazo-pyrazoles showed interesting anti-angiogenic action, being able to interfere with ERK1/2, AKT and p38MAPK phosphorylation in different manners and with different potenc…
View article: Induced Pluripotent Stem Cells to Understand Mucopolysaccharidosis. I: Demonstration of a Migration Defect in Neural Precursors
Induced Pluripotent Stem Cells to Understand Mucopolysaccharidosis. I: Demonstration of a Migration Defect in Neural Precursors Open
Background: Mucopolysaccharidosis type I-Hurler (MPS1-H) is a severe genetic lysosomal storage disorder due to loss-of-function mutations in the IDUA gene. The subsequent complete deficiency of alpha l-iduronidase enzyme is directly respon…
View article: Characterization of Proangiogenic Monocytes from Blood in Patients with Chronic Ischemic Diabetic Foot Ulcers and Controls
Characterization of Proangiogenic Monocytes from Blood in Patients with Chronic Ischemic Diabetic Foot Ulcers and Controls Open
Many persons with diabetes mellitus have limb ischemia, which is a major clinical problem. A subset of human monocytes that expresses TIE-2 may enhance neovascularization. We performed 179 phlebotomies on 142 patients (or donors), includin…
View article: The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma
The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma Open
These data highlight the interest for the sVE bioassay in future follow-up of cancer patients treated with targeted therapies such as tyrosine-kinase inhibitors.
View article: Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours
Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours Open
View article: The pyrazolyl-urea GeGe3 inhibits tumor angiogenesis and reveals dystrophia myotonica protein kinase (DMPK)1 as a novel angiogenesis target
The pyrazolyl-urea GeGe3 inhibits tumor angiogenesis and reveals dystrophia myotonica protein kinase (DMPK)1 as a novel angiogenesis target Open
The limitation of targeting VEGF/VEGFR2 signalling to stop angiogenesis in cancer therapy has been blamed on re-activation of alternative receptor tyrosine kinases by compensatory angiogenic factors. Targeting MAPK and PI3K signaling pathw…