Adarsh Babu
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View article: BI16 The COAST (Contemporary Outcomes After cutaneous SCC in Transplant recipients) study: final results and implications for management following the first cutaneous squamous cell carcinoma in kidney transplant recipients
BI16 The COAST (Contemporary Outcomes After cutaneous SCC in Transplant recipients) study: final results and implications for management following the first cutaneous squamous cell carcinoma in kidney transplant recipients Open
Cutaneous squamous cell carcinoma (cSCC) is the most common post-transplant malignancy. Historical studies indicate that up to 25% of organ transplant recipients will develop a new cSCC within 12 months of their first cSCC, with doubled me…
View article: Ongoing equipoise contributes to unchanged outcomes and significant morbidity following post-transplant cutaneous squamous cell carcinoma: A Multicentre Cohort Study
Ongoing equipoise contributes to unchanged outcomes and significant morbidity following post-transplant cutaneous squamous cell carcinoma: A Multicentre Cohort Study Open
Introduction Cutaneous squamous cell carcinoma (CSCC) is the most common post-transplant malignancy, ultimately affecting up to half of all recipients. Historical cohort studies indicate that up to 25% of recipients develop further post-tr…
View article: Polycystic Ovary Syndrome: A Comprehensive Review of Its Clinical Presentation, Comorbidities, Long-Term Complications and Management
Polycystic Ovary Syndrome: A Comprehensive Review of Its Clinical Presentation, Comorbidities, Long-Term Complications and Management Open
Polycystic Ovary Syndrome is a common hormonal and metabolic disorder that affects many women of reproductive age and can lead to symptoms of irregular menstruation, hirsutism, acne, and weight gain. It can also contribute to health proble…
View article: Unmasking the Dangers of Fairness Creams: A Review of Heavy Metal Content and Its Nephrotoxic Effects
Unmasking the Dangers of Fairness Creams: A Review of Heavy Metal Content and Its Nephrotoxic Effects Open
The skin- whitening creams have been a huge part of society for a fair skin complexion. The benchmark of beauty in many parts of the world today has been entrenched in cultural and historical settings for centuries. These creams may pose s…
View article: The ASK trial: a randomised controlled feasibility trial and process evaluation of a complex multicomponent intervention to improve AccesS to living-donor Kidney transplantation
The ASK trial: a randomised controlled feasibility trial and process evaluation of a complex multicomponent intervention to improve AccesS to living-donor Kidney transplantation Open
Background Following identification of barriers to living-donor kidney transplantation, and subsequent development of a multicomponent intervention, we undertook a feasibility trial of the intervention. Trial design Two-arm, parallel group…
View article: BI12 How should we manage transplant recipients after a first cutaneous squamous cell carcinoma? An update from the UK COAST (Contemporary Outcomes After cutaneous SCC in Transplant recipients) study
BI12 How should we manage transplant recipients after a first cutaneous squamous cell carcinoma? An update from the UK COAST (Contemporary Outcomes After cutaneous SCC in Transplant recipients) study Open
After first cutaneous squamous cell carcinoma (cSCC), up to 75% of kidney transplant recipients (KTRs) will develop further cSCC and their risk of metastasis is increased. Evidence is limited regarding which secondary prevention strategies…
View article: Expectations of a new opt‐out system of consent for deceased organ donation in England: A qualitative interview study
Expectations of a new opt‐out system of consent for deceased organ donation in England: A qualitative interview study Open
Introduction In 2020 England moved to an opt‐out deceased donation law. We aimed to investigate the views of a mixed stakeholder group comprising people with kidney disease, family members and healthcare practitioners towards the change in…
View article: Defining Clinically Pathogenic HLA-Specific Antibodies - Granular Details in Characteristics in Pre and Early Time Following HLA-Antibody Incompatible Kidney Transplantation
Defining Clinically Pathogenic HLA-Specific Antibodies - Granular Details in Characteristics in Pre and Early Time Following HLA-Antibody Incompatible Kidney Transplantation Open
Antibodies against donor HLA determine access to solid organ transplantation and in many cases the outcome of transplantation, but graft failure is not an inevitable consequence of their presence. Much research has been performed with two …
View article: Development of an intervention to improve access to living-donor kidney transplantation (the ASK study)
Development of an intervention to improve access to living-donor kidney transplantation (the ASK study) Open
A living-donor kidney transplant (LDKT) is one of the best treatments for kidney failure. The UK’s LDKT activity falls behind that of many other countries, and there is evidence of socioeconomic inequity in access. We aimed to develop a UK…
View article: C3d‐positive donor‐specific antibodies have a role in pretransplant risk stratification of cross‐match‐positive HLA‐incompatible renal transplantation: United Kingdom multicentre study
C3d‐positive donor‐specific antibodies have a role in pretransplant risk stratification of cross‐match‐positive HLA‐incompatible renal transplantation: United Kingdom multicentre study Open
Anti-HLA-antibody characteristics aid to risk-stratify patients and improve long-term renal graft outcomes. Complement activation by donor-specific antibody (DSA) is an important characteristic that may determine renal allograft outcome. T…
View article: SAT-507 Pneumocystis Carinii Pneumonia: A Rare Cause of Granulomatous Hypercalcemia
SAT-507 Pneumocystis Carinii Pneumonia: A Rare Cause of Granulomatous Hypercalcemia Open
Pneumocystis Carinii pneumonia (PCP) is a well-known complication of immunosuppression. Scattered case reports have linked PCP and its ability to induce a granulomatous response to hypercalcemia. PCP related hypercalcemia appears to be res…
View article: Significance of the intraindividual variability of HLA IgG antibodies in renal disease patients observed with different beadsets monitored with two different secondary antibodies on a Luminex platform
Significance of the intraindividual variability of HLA IgG antibodies in renal disease patients observed with different beadsets monitored with two different secondary antibodies on a Luminex platform Open
The accurate measurement of anti-HLA alloantibodies in transplant candidates is required for determining the degree of sensitization and for the listing of unacceptable antigens for organ allocation. Both the configuration of the HLA molec…