Adarsh Dharmarajan
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View article: Survival Outcome of Patients with Vulvar Malignancy Treated at a Tertiary Care Cancer Centre: A Cohort Study
Survival Outcome of Patients with Vulvar Malignancy Treated at a Tertiary Care Cancer Centre: A Cohort Study Open
Introduction: Vulvar malignancy is a rare gynaecological malignancy and understanding the determinants of vulvar cancer outcomes is essential for improving patient care and guiding future research in this field. The management of vulvar ma…
View article: Survival Outcome of Patients with Vaginal Malignancy: A 10-year Cohort Study from Tertiary Care Centre, Southern India
Survival Outcome of Patients with Vaginal Malignancy: A 10-year Cohort Study from Tertiary Care Centre, Southern India Open
Introduction: Vaginal malignancy is a rare gynaecological malignancy, and authors know little about its survival and prognostic factors. The management of vaginal malignancies is largely determined by factors such as histological type, tum…
View article: Community Participatory Approach in Cancer Control: “The Kannapuram Model” for Breast Cancer Control in Northern Kerala, India
Community Participatory Approach in Cancer Control: “The Kannapuram Model” for Breast Cancer Control in Northern Kerala, India Open
Background: Breast cancer accounts for 26.6% of cancers among Indian women. Lack of awareness and fear lead to late-stage presentations and high mortality. This study aims to describe a novel community participatory model for cancer contro…
View article: Origin and survival outcomes of Pseudomyxoma peritonei—A retrospective study
Origin and survival outcomes of Pseudomyxoma peritonei—A retrospective study Open
Background: Pseudomyxoma peritonei (PMP) is an unusual clinical condition typically presenting with widespread mucinous neoplastic lesions within the peritoneum resulting in gelatin material-rich ascites. It was first described by Werth in…
View article: Genomic analysis of breast cancer patients from Kerala: A novel BRCA1 mutation detected
Genomic analysis of breast cancer patients from Kerala: A novel BRCA1 mutation detected Open
BACKGROUND: Breast cancer is the most common cancer among females, with an incidence of 6,41,000 cases annually. The genetic makeup of the individuals, ethnicity, geographical location, lifestyle, and BMI are some well-described factors as…
View article: Dynamic analysis of serum Ca-125 levels during neoadjuvant chemotherapy in patients with advanced epithelial ovarian cancer: a retrospective study
Dynamic analysis of serum Ca-125 levels during neoadjuvant chemotherapy in patients with advanced epithelial ovarian cancer: a retrospective study Open
Background: Assessment of CA-125 kinetics was commonly used as a tool for tumor response to chemotherapy in ovarian cancer patients. The study aimed to determine any logarithmic/linear relationship between pre-chemotherapy and pre-operativ…
View article: Re-staging surgery in endometrial cancer: an audit on its value
Re-staging surgery in endometrial cancer: an audit on its value Open
Background: Incomplete surgical staging in carcinoma endometrium is not an uncommon entity in developing world. Proper surgical staging has got a role in prognostication and planning adjuvant treatment. So, an audit was done to assess the …
View article: Short-course adjuvant trastuzumab in breast cancer: Experience from a tertiary cancer center in rural India
Short-course adjuvant trastuzumab in breast cancer: Experience from a tertiary cancer center in rural India Open
Introduction: Majority of the patients in low-to-middle income countries (LMICs) have no access to adjuvant trastuzumab due to financial constraints. Short-course (9 weeks) schedule of trastuzumab is a feasible alternative in this setting.…
View article: Impact of perioperative period on disease-free survival among carcinoma ovary patients treated with the interval cyto-reductive surgery at a tertiary cancer centre in Kerala, India: a retrospective study
Impact of perioperative period on disease-free survival among carcinoma ovary patients treated with the interval cyto-reductive surgery at a tertiary cancer centre in Kerala, India: a retrospective study Open
Background: Global incidence of ovarian malignancies is 300,000 as per GLOBOCAN 2018. The treatment protocol for advanced ovarian malignancies (stage IIIc and stage IV) includes neo-adjuvant chemotherapy and surgery followed by adjuvant ch…
View article: The incidence and risk factors for development of lower limb lymphedema after treatment for gynaecological cancers
The incidence and risk factors for development of lower limb lymphedema after treatment for gynaecological cancers Open
Background: The development of postoperative lower limb lymphedema (LLL) is a disabling, yet usually overlooked sequele of most gynecological cancer treatment. It can lead to significant functional problems that negatively affect gynecolog…
View article: Audit on early stage carcinoma cervix primarily treated with radical surgery: A tertiary cancer care centre experience
Audit on early stage carcinoma cervix primarily treated with radical surgery: A tertiary cancer care centre experience Open
Introduction: Clinical staging is universally accepted for ca cervix. In early stage of carcinoma cervix both radiation and radical hysterectomy given equivalent local control rates as well as survival. Poor prognostic factors following su…