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View article: Adenotonsillectomy for Snoring and Mild Sleep Apnea in Children
Adenotonsillectomy for Snoring and Mild Sleep Apnea in Children Open
Importance The utility of adenotonsillectomy in children who have habitual snoring without frequent obstructive breathing events (mild sleep-disordered breathing [SDB]) is unknown. Objectives To evaluate early adenotonsillectomy compared w…
View article: <i>Arap1</i> loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death
<i>Arap1</i> loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death Open
Retinitis pigmentosa (RP), a retinal degenerative disease, is the leading cause of heritable blindness. Previously, we described that Arap1−/− mice develop a similar pattern of photoreceptor degeneration. Arap1 is an Arf-directed GTPase-ac…
View article: <i>Arap1</i> Deficiency Causes Photoreceptor Degeneration in Mice
<i>Arap1</i> Deficiency Causes Photoreceptor Degeneration in Mice Open
Arap1 is necessary for normal photoreceptor survival in mice, and may be a novel gene relevant to human retinal degenerative processes, although its mechanism is unknown. Further studies in this mouse model of retinal degeneration will giv…