Adebayo Anjorin
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View article: Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group
Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group Open
View article: Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors Open
View article: Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology Open
View article: Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors Open
Suicide is a leading cause of death worldwide and non-fatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both are known to have a substantial genetic etiology, which is…
View article: Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs Open
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across disorders is unclear. To examine shared genetic etiology, we use genome-wide genotype d…
View article: Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology
Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology Open
Bipolar disorder (BD) is a heritable mental illness with complex etiology. We performed a genome-wide association study (GWAS) of 41,917 BD cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci. BD ri…
View article: Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders Open
View article: The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls Open
View article: GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores Open
This study provides new information on genetic associations and demonstrates that genetic liability for major depression increases risk for suicide attempt across psychiatric disorders. Further collaborative efforts to increase sample size…
View article: Genome-wide association study identifies 30 loci associated with bipolar disorder
Genome-wide association study identifies 30 loci associated with bipolar disorder Open
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with P < 1 × 10-4…
View article: Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores
Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores Open
Objective Over 90% of suicide attempters have a psychiatric diagnosis, however twin and family studies suggest that the genetic etiology of suicide attempt (SA) is partially distinct from that of the psychiatric disorders themselves. Here,…
View article: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes Open
View article: Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes Open
Schizophrenia (SCZ) and bipolar disorder (BD) are highly heritable disorders that share a significant proportion of common risk variation. Understanding the genetic factors underlying the specific symptoms of these disorders will be crucia…
View article: Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder
Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder Open
Bipolar disorder is a highly heritable psychiatric disorder that features episodes of mania and depression. We performed the largest genome-wide association study to date, including 20,352 cases and 31,358 controls of European descent, wit…
View article: Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder
Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder Open
We identified six nonsynonymous and six synonymous variants. We genotyped three rare nonsynonymous variants, rs374866393, rs148346599 and rs200629713, in a total of 1099 BPD samples and 1056 controls. Burden analysis of these rare variants…
View article: Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder
Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder Open
View article: Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways Open