Adeeb Shehzad
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View article: Future Aspects of Nanotechnology in Therapeutics: A Comprehensive Review of Materials, Applications, and Future Directions
Future Aspects of Nanotechnology in Therapeutics: A Comprehensive Review of Materials, Applications, and Future Directions Open
Nanotechnology is rapidly reshaping the landscape of modern medicine, offering innovative solutions for the diagnosis, treatment, and prevention of complex diseases. This review presents a comprehensive overview of recent advancements in n…
View article: Bacterial cellulose–Aloe praetermissa hydrogels for enhanced antibacterial and biocompatible wound care
Bacterial cellulose–Aloe praetermissa hydrogels for enhanced antibacterial and biocompatible wound care Open
View article: Frankincense: A potential phytotherapeutic agent in cancer treatment
Frankincense: A potential phytotherapeutic agent in cancer treatment Open
Plant-isolated compounds are the roadmap for the modern pharmaceutical industry due to the anticancer activities of their bioactive constituents and metabolites. Boswellia sacra (Burseraceae) oleo gum resin has cytotoxic potential for the …
View article: Chemopreventive Effects of Resveratrol and Curcumin on Melanoma Growth in C57BL/6 Mice
Chemopreventive Effects of Resveratrol and Curcumin on Melanoma Growth in C57BL/6 Mice Open
This study investigates the chemopreventive potential of two phytochemicals, resveratrol (RV) and curcumin (CUR), in a C57BL/6 mouse model of melanoma. Utilizing a xenograft approach, we implanted B16F10 cells subcutaneously into mice and …
View article: Nanomedicine in oncology: Diagnostic breakthroughs and therapeutic Frontiers
Nanomedicine in oncology: Diagnostic breakthroughs and therapeutic Frontiers Open
Nanomedicine is a multidisciplinary field, offering significant promises for cancer detection and therapy. Nanoparticles (NPs), nanoprobes and nanobiosensors can be tailored to achieve highly sensitive tumor detection by contrast imaging t…
View article: From Bioinks to Functional Tissues and Organs: Advances, Challenges, and the Promise of 3D Bioprinting
From Bioinks to Functional Tissues and Organs: Advances, Challenges, and the Promise of 3D Bioprinting Open
3D printing, particularly bioprinting, has emerged as a transformative technology in tissue engineering and regenerative medicine, enabling the precise layer‐by‐layer fabrication of living tissues and complex biomaterials. Bioprinting has …
View article: Green-synthesized silver nanoparticle-infused PVA hydrogels: A sustainable solution for skin repair
Green-synthesized silver nanoparticle-infused PVA hydrogels: A sustainable solution for skin repair Open
View article: Transdermal Glucose Responsive Composite Polymeric Microneedle Patches for Personalized Diabetes Treatment: A Novel Approach to Precision Medicine
Transdermal Glucose Responsive Composite Polymeric Microneedle Patches for Personalized Diabetes Treatment: A Novel Approach to Precision Medicine Open
View article: Synergetic interplay of a nitrogen- and sulfur-rich copper bi-linker 2D cubic-layered MOF composite with MXene for improved hybrid supercapacitor application
Synergetic interplay of a nitrogen- and sulfur-rich copper bi-linker 2D cubic-layered MOF composite with MXene for improved hybrid supercapacitor application Open
To combine the properties of batteries and capacitors in a single hybrid device, metal–organic frameworks composite with MXene have emerged as promising materials.
View article: Basal Cell Carcinoma
Basal Cell Carcinoma Open
Globally, Basal cell carcinoma is the most prevalent form of skin cancer, which originates from basal cells of the epidermis. Sun-exposed parts of the body (head, face, and neck) are mostly affected by BCC. Characteristics of BCC include l…
View article: Camptothecin-loaded mesoporous silica nanoparticles functionalized with CpG oligodeoxynucleotide as a new approach for skin cancer treatment
Camptothecin-loaded mesoporous silica nanoparticles functionalized with CpG oligodeoxynucleotide as a new approach for skin cancer treatment Open
The therapeutic efficacy of camptothecin (CPT), a potent antitumor alkaloid, is hindered by its hydrophobic nature and instability, limiting its clinical use in treating cutaneous squamous cell carcinoma (SCC). This study introduces a nove…
View article: Development of pH-Responsive Nano Drug Delivery System for Efficient Loading and Release of Hydrophobic Anticancer Drugs
Development of pH-Responsive Nano Drug Delivery System for Efficient Loading and Release of Hydrophobic Anticancer Drugs Open
The practical application of a pH-responsive Nanoparticle Drug Delivery System (NDDS) in cancer treatment is often hampered by several issues such as the protection of therapeutic molecules from external stresses, inefficient targeted deli…
View article: Retraction Note: Inhibition of NF-κB signaling and HSP70/HSP90 proteins by newly synthesized hydrazide derivatives in arthritis model
Retraction Note: Inhibition of NF-κB signaling and HSP70/HSP90 proteins by newly synthesized hydrazide derivatives in arthritis model Open
View article: Enhancing Security Via Speaker Recognition
Enhancing Security Via Speaker Recognition Open
View article: Diagnostic and Therapeutic Potential of Circulating-Free DNA and Cell-Free RNA in Cancer Management
Diagnostic and Therapeutic Potential of Circulating-Free DNA and Cell-Free RNA in Cancer Management Open
Over time, molecular biology and genomics techniques have been developed to speed up the early diagnosis and clinical management of cancer. These therapies are often most effective when administered to the subset of malignancies harboring …
View article: Mosquirix™ RTS, S/AS01 Vaccine Development, Immunogenicity, and Efficacy
Mosquirix™ RTS, S/AS01 Vaccine Development, Immunogenicity, and Efficacy Open
Malaria is a parasitic infection caused by bites from Plasmodium falciparum (P. falciparum)-infected mosquitoes with a present scale of symptoms ranging from moderate fever to neurological disorders. P. falciparum is the most lethal of the…
View article: Biological Potentials and Phytochemical Constituents of Raw and Roasted Nigella arvensis and Nigella sativa
Biological Potentials and Phytochemical Constituents of Raw and Roasted Nigella arvensis and Nigella sativa Open
Nigella species are widely used to cure various ailments. Their health benefits, particularly from the seed oils, could be attributed to the presence of a variety of bioactive components. Roasting is a critical process that has historicall…
View article: Thymus Gland: A Double Edge Sword for Coronaviruses
Thymus Gland: A Double Edge Sword for Coronaviruses Open
The thymus is the main lymphoid organ that regulates the immune and endocrine systems by controlling thymic cell proliferation and differentiation. The gland is a primary lymphoid organ responsible for generating mature T cells into CD4+ o…
View article: Physiological and Cellular Functions of Vitamin K on Cardiovascular Function
Physiological and Cellular Functions of Vitamin K on Cardiovascular Function Open
This chapter reviews the physiological and cellular functions of vitamin K in the cardiovascular system based on the latest pre-clinical and clinical evidence. Vitamin K belongs to a family of structurally similar fat-soluble vitamins, act…
View article: An Update on the Role of Dietary Phytochemicals in Human Skin Cancer: New Insights into Molecular Mechanisms
An Update on the Role of Dietary Phytochemicals in Human Skin Cancer: New Insights into Molecular Mechanisms Open
Human skin is continuously subjected to environmental stresses, as well as extrinsic and intrinsic noxious agents. Although skin adopts various molecular mechanisms to maintain homeostasis, excessive and repeated stresses can overwhelm the…
View article: Bacillus amyloliquefaciens RWL-1 as a New Potential Strain for Augmenting Biochemical and Nutritional Composition of Fermented Soybean
Bacillus amyloliquefaciens RWL-1 as a New Potential Strain for Augmenting Biochemical and Nutritional Composition of Fermented Soybean Open
Soybean (Glycine max L.) is a good source of natural antioxidants and commonly consumed as fermented products such as cheonggukjang, miso, tempeh, and sufu in Asian countries. The aim of the current study was to examine the influence of no…
View article: Intranasal Delivery of Nanoformulations: A Potential Way of Treatment for Neurological Disorders
Intranasal Delivery of Nanoformulations: A Potential Way of Treatment for Neurological Disorders Open
Although the global prevalence of neurological disorders such as Parkinson’s disease, Alzheimer’s disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing, effective delivery of drug molecules in therapeutic quantitie…
View article: OP5 Stage IV breast cancer: Factors affecting survival rates in a tertiary institution, a 7-year experience
OP5 Stage IV breast cancer: Factors affecting survival rates in a tertiary institution, a 7-year experience Open
model of screening which is stratified according to an individuals' risk would appear logical and this idea has been considered internationally and in Australia for the last few years.How Australian women view this approach is largely unkn…
View article: Lirioresinol B dimethyl ether inhibits NF-κB and COX-2 and activates IκBα expression in CCl4-induced hepatic fibrosis
Lirioresinol B dimethyl ether inhibits NF-κB and COX-2 and activates IκBα expression in CCl4-induced hepatic fibrosis Open
View article: Additional file 1 of Lirioresinol B dimethyl ether inhibits NF-κB and COX-2 and activates IκBα expression in CCl4-induced hepatic fibrosis
Additional file 1 of Lirioresinol B dimethyl ether inhibits NF-κB and COX-2 and activates IκBα expression in CCl4-induced hepatic fibrosis Open
Additional file 1. SI values calculation file.
View article: Synthesis, anticancer, molecular docking and QSAR studies of benzoylhydrazone
Synthesis, anticancer, molecular docking and QSAR studies of benzoylhydrazone Open
To find out effective anticancer compounds we synthesized (1–30) derivatives of 4-isopropylbenzoylhydrazone and evaluated for anticancer potential. The compounds 3, 9, 12, 23, 26 and 28 showed better activities ranging (0.39–1.1 µg/ml) tha…
View article: A NATURAL PRODUCT DECURSIN ENHANCES THE RADIOSENSITIZATION OF IONIZING RADIATION AGAINST DMBA-INDUCED TUMOR
A NATURAL PRODUCT DECURSIN ENHANCES THE RADIOSENSITIZATION OF IONIZING RADIATION AGAINST DMBA-INDUCED TUMOR Open
Objective: Radiation therapy has gained significant attention for the treatment and prevention of solid and malignant human tumors. However, after periodical exposures, radiation therapy losses its efficacy against cancer cells displaying …
View article: Methanolic Extract of<i>Artemia salina</i>Eggs and Various Fractions in Different Solvents Contain Potent Compounds That Decrease Cell Viability of Colon and Skin Cancer Cell Lines and Show Antibacterial Activity against<i>Pseudomonas aeruginosa</i>
Methanolic Extract of<i>Artemia salina</i>Eggs and Various Fractions in Different Solvents Contain Potent Compounds That Decrease Cell Viability of Colon and Skin Cancer Cell Lines and Show Antibacterial Activity against<i>Pseudomonas aeruginosa</i> Open
Artemia salina, crustaceans of class Branchiopoda and order Anostraca, are living and reproducing only in highly saline natural lakes and in other reservoirs where sea water is evaporated to produce salt. Artemia salina eggs can be purchas…
View article: Peer Review #3 of "Synthesis, characterization and antibacterial activity of silver nanoparticles using Rhazya stricta (v0.2)"
Peer Review #3 of "Synthesis, characterization and antibacterial activity of silver nanoparticles using Rhazya stricta (v0.2)" Open
Background Green synthesis of metallic nanoparticles has gained significant attention in the field of nano-medicine due to environment-friendly and cost-effective alternative in comparison to other physical and chemical methods.Several met…
View article: Peer Review #1 of "Synthesis, characterization and antibacterial activity of silver nanoparticles using Rhazya stricta (v0.2)"
Peer Review #1 of "Synthesis, characterization and antibacterial activity of silver nanoparticles using Rhazya stricta (v0.2)" Open
Background Green synthesis of metallic nanoparticles has gained significant attention in the field of nano-medicine due to environment-friendly and cost-effective alternative in comparison to other physical and chemical methods.Several met…