Adele Costabile
YOU?
Author Swipe
View article: Ethnic differences in adipose tissue dysfunction and insulin resistance: a scoping review
Ethnic differences in adipose tissue dysfunction and insulin resistance: a scoping review Open
Current trends indicate intrahepatic lipid is lower in BA but greater in SA compared to WE populations, indicting possible ethnic disparities in the role ATD in the development of T2D. Few ethnicity studies have investigated multiple chara…
View article: Fermented beetroot modulates gut microbial carbohydrate metabolism in prediabetes and prevents high-fat diet induced hyperglycemia in a prediabetic model
Fermented beetroot modulates gut microbial carbohydrate metabolism in prediabetes and prevents high-fat diet induced hyperglycemia in a prediabetic model Open
The global increase in prevalence of (pre-)diabetes demands immediate intervention strategies. In our earlier work, we demonstrated in vitro antidiabetic potential of a fermented beetroot product (PN39). Here, we examined the impact of PN3…
View article: A preliminary examination of gut microbiota and emotion regulation in 2- to 6-year-old children
A preliminary examination of gut microbiota and emotion regulation in 2- to 6-year-old children Open
Background It is well known that having maladaptive emotion regulation skills during childhood may predict mental health issues later in life, therefore, establishing links with gut microbiome could help develop gut-derived interventions d…
View article: Impact of Combined Prebiotic Galacto-Oligosaccharides and Bifidobacterium breve-Derived Postbiotic on Gut Microbiota and HbA1c in Prediabetic Adults: A Double-Blind, Randomized, Placebo-Controlled Study
Impact of Combined Prebiotic Galacto-Oligosaccharides and Bifidobacterium breve-Derived Postbiotic on Gut Microbiota and HbA1c in Prediabetic Adults: A Double-Blind, Randomized, Placebo-Controlled Study Open
The complex interactions between intestinal microbiota and metabolic disorders are well-documented, with implications for glucose metabolism, energy expenditure, and intestinal permeability. Prebiotics induce beneficial changes in gut micr…
View article: Adherence to unhealthy diets is associated with altered frontal gamma-aminobutyric acid and glutamate concentrations and grey matter volume: preliminary findings
Adherence to unhealthy diets is associated with altered frontal gamma-aminobutyric acid and glutamate concentrations and grey matter volume: preliminary findings Open
Adhering to unhealthy dietary patterns may be associated with compromised E/I balance, and this could affect GMV, and subsequently, rumination.
View article: Probiotic Interventions in Coeliac Disease: A Systematic Review with a Focus on Cardiovascular Risk
Probiotic Interventions in Coeliac Disease: A Systematic Review with a Focus on Cardiovascular Risk Open
People with coeliac disease (CD) have a higher risk of developing cardiovascular disease (CVD), potentially due to inflammation. Probiotics can influence CVD risk through several mechanisms including modifying inflammation. We performed a …
View article: Supplementation with postbiotic from Bifidobacterium Breve BB091109 improves inflammatory status and endocrine function in healthy females: a randomized, double-blind, placebo-controlled, parallel-groups study
Supplementation with postbiotic from Bifidobacterium Breve BB091109 improves inflammatory status and endocrine function in healthy females: a randomized, double-blind, placebo-controlled, parallel-groups study Open
This study evaluated the effects of dietary supplementation with a postbiotic extract of Bifidobacterium breve BB091109 on pro-inflammatory cytokines levels and markers of endocrine function. A prospective, double-blind, placebo-controlled…
View article: Cooking, Digestion, and In Vitro Colonic Fermentation of Nigerian Wholegrains Affect Phenolic Acid Metabolism and Gut Microbiota Composition
Cooking, Digestion, and In Vitro Colonic Fermentation of Nigerian Wholegrains Affect Phenolic Acid Metabolism and Gut Microbiota Composition Open
Wholegrains contain both fibre and phenolic acids (PAs), and their gastrointestinal modifications are critical for their bioavailability and bioactivity. We evaluated the modifications on the PA profile and gut microbiota composition of se…
View article: Personality, dietary identity, mental and sleep health in vegans and vegetarians: A preliminary cross‐sectional study
Personality, dietary identity, mental and sleep health in vegans and vegetarians: A preliminary cross‐sectional study Open
Background and Aims Plant‐based diets have gained popularity over the past decade. However, research regarding mental and sleep health benefits of following plant‐based diets are conflicting. As there are associations between mental/sleep …
View article: Comparison of the relative impacts of acute consumption of an inulin-enriched diet, milk kefir or a commercial probiotic product on the human gut microbiome and metabolome
Comparison of the relative impacts of acute consumption of an inulin-enriched diet, milk kefir or a commercial probiotic product on the human gut microbiome and metabolome Open
It has been established that the human gut microbiota is central to health, and, consequently, there has been a growing desire to positively modulate its composition and/or function through, for example, the use of fermented foods, prebiot…
View article: The gut microbiome meets nanomaterials: exposure and interplay with graphene nanoparticles
The gut microbiome meets nanomaterials: exposure and interplay with graphene nanoparticles Open
We provide a brief overview of graphene-based nanoparticles, their usage and characteristics. We discuss experimental data from in vitro screening tests on small animal experiments related to exposure and the effects of graphene nanopartic…
View article: Cerrado and Pantanal fruit flours affect gut microbiota composition in healthy and <scp>post‐COVID</scp> ‐19 individuals: an <i>in vitro</i> pilot fermentation study
Cerrado and Pantanal fruit flours affect gut microbiota composition in healthy and <span>post‐COVID</span> ‐19 individuals: an <i>in vitro</i> pilot fermentation study Open
Summary Cerrado and Pantanal plants can provide fruits with high nutritional value and antioxidants. This study aims to evaluate four fruit flours (from jatobá pulp, cumbaru almond, bocaiuva pulp and bocaiuva almond) and their effects on t…
View article: Wholegrain fermentation affects gut microbiota composition, phenolic acid metabolism and pancreatic beta cell function in a rodent model of type 2 diabetes
Wholegrain fermentation affects gut microbiota composition, phenolic acid metabolism and pancreatic beta cell function in a rodent model of type 2 diabetes Open
The intestinal microbiota plays an important role in host metabolism via production of dietary metabolites. Microbiota imbalances are linked to type 2 diabetes (T2D), but dietary modification of the microbiota may promote glycemic control.…
View article: Calcium and Iron Content of Cereal-Based Gluten-Free Products
Calcium and Iron Content of Cereal-Based Gluten-Free Products Open
The impact of a gluten-free (GF) diet on the intake of calcium and iron is broadly unknown, as the micronutrient content of GF cereal-based products has scarcely been measured. The study aimed to measure the calcium and iron content of GF …
View article: An In Vitro Pilot Fermentation Study on the Impact of Chlorella pyrenoidosa on Gut Microbiome Composition and Metabolites in Healthy and Coeliac Subjects
An In Vitro Pilot Fermentation Study on the Impact of Chlorella pyrenoidosa on Gut Microbiome Composition and Metabolites in Healthy and Coeliac Subjects Open
The response of a coeliac and a healthy gut microbiota to the green algae Chlorella pyrenoidosa was evaluated using an in vitro continuous, pH controlled, gut model system, which simulated the human colon. The effect of C. pyrenoidosa on t…
View article: Clinical Efficacy of Brown Seaweeds Ascophyllum nodosum and Fucus vesiculosus in the Prevention or Delay Progression of the Metabolic Syndrome: A Review of Clinical Trials
Clinical Efficacy of Brown Seaweeds Ascophyllum nodosum and Fucus vesiculosus in the Prevention or Delay Progression of the Metabolic Syndrome: A Review of Clinical Trials Open
Metabolic syndrome (MetS) is a global public health problem affecting nearly 25.9% of the world population characterised by a cluster of disorders dominated by abdominal obesity, high blood pressure, high fasting plasma glucose, hypertriac…
View article: The impact of cooking and digestion on the phenolic acid content of selected Nigerian and UK grown wholegrains
The impact of cooking and digestion on the phenolic acid content of selected Nigerian and UK grown wholegrains Open
An abstract is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the ‘Save PDF’ action button.
View article: Comparative Evaluation of the Antimicrobial and Mucus Induction Properties of Selected Bacillus Strains against Enterotoxigenic Escherichia coli
Comparative Evaluation of the Antimicrobial and Mucus Induction Properties of Selected Bacillus Strains against Enterotoxigenic Escherichia coli Open
Probiotics have been shown to bind to host receptors, which are important for pathogen adhesion and induce the host’s production of defence factors. They can activate the goblet-cell-derived production of mucins, a major component of the m…
View article: Impact of lignans in oilseed mix on gut microbiome composition and enterolignan production in younger healthy and premenopausal women: an in vitro pilot study
Impact of lignans in oilseed mix on gut microbiome composition and enterolignan production in younger healthy and premenopausal women: an in vitro pilot study Open
Background: Dietary lignans belong to the group of phytoestrogens together with coumestans, stilbenes and isoflavones, and themselves do not exhibit oestrogen-like properties. Nonetheless, the gut microbiota converts them into enterolignan…
View article: Nutrient composition of commercially available compared with prescription only gluten-free bread and flour mixes in England
Nutrient composition of commercially available compared with prescription only gluten-free bread and flour mixes in England Open
There has been a global increase in gluten-free foods market and perceived health benefits are portrayed in the media. UK legislation requires wheat flour to be fortified with calcium, this is not the case for gluten-free (GF) flours. Calc…