Adele Pinnock
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View article: Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet
Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet Open
AIMS: Obesity during pregnancy increases risk of cardiovascular disease (CVD) in the offspring and individuals exposed to over-nutrition during fetal life are likely to be exposed to a calorie-rich environment postnatally. Here, we establi…
View article: Exploring the impact of maternal obesity on offspring renal morphology and later life health
Exploring the impact of maternal obesity on offspring renal morphology and later life health Open
It is well established that exposure to adverse environments in early life including both maternal under and over-nutrition predisposes individuals to similar adverse traditionally adult onset diseases such as the metabolic syndrome. Epide…
View article: Maternal overnutrition programs cardiac dysfunction independently of post-natal diet in mice
Maternal overnutrition programs cardiac dysfunction independently of post-natal diet in mice Open
PURPOSE Gestational exposure to maternal obesity increases the risk of cardiovascular disease in the offspring. Exposure to overnutrition during fetal life is likely to be followed by continued exposure to the same calorie-rich environment…
View article: 180 Early Life Exposure to Maternal Obesity Perturbs Renal Morphology in Mice
180 Early Life Exposure to Maternal Obesity Perturbs Renal Morphology in Mice Open
Introduction The incidence of Chronic Kidney Disease (CKD) has risen globally by 83% since 1990, concurrently with type 2 diabetes and metabolic syndrome. Studies of maternal under-nutrition during pregnancy have highlighted that the kidne…