Mengqi Zhou
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View article: Baculovirus enhances arginine uptake and induces mitochondrial autophagy to promote viral proliferation
Baculovirus enhances arginine uptake and induces mitochondrial autophagy to promote viral proliferation Open
As obligatory intracellular parasites, viruses must rely on metabolic reprogramming of host cells to meet their replication needs. Baculovirus is an important biopesticide and a vector for the preparation of biological products. In additio…
View article: piR-bmo-796514 Facilitates the Proliferation of Exogenous DNA Virus (Baculovirus) by Targeting the Host E3 Ubiquitin Ligase RNF181
piR-bmo-796514 Facilitates the Proliferation of Exogenous DNA Virus (Baculovirus) by Targeting the Host E3 Ubiquitin Ligase RNF181 Open
PIWI-interacting RNAs (piRNAs), a class of 23-31 nucleotide non-coding RNAs, are known for silencing transposons and endogenous retroviruses that reside in animal genomes. However, the mechanisms by which host piRNAs affect exogenous viral…
View article: Quantitative analysis and clinical determinants of orthodontically induced root resorption using automated tooth segmentation from CBCT imaging
Quantitative analysis and clinical determinants of orthodontically induced root resorption using automated tooth segmentation from CBCT imaging Open
This study applied a deep learning model to accurately assess root volume changes using CBCT, revealing significant root volume reduction after orthodontic treatment. It found that underage patients experienced less root resorption, while …
View article: SceneX: Procedural Controllable Large-Scale Scene Generation
SceneX: Procedural Controllable Large-Scale Scene Generation Open
Developing comprehensive explicit world models is crucial for understanding and simulating real-world scenarios. Recently, Procedural Controllable Generation (PCG) has gained significant attention in large-scale scene generation by enablin…
View article: Quantitative Analysis and Clinical Determinants of Orthodontically Induced Root Resorption Using Automated Tooth Segmentation from CBCT Imaging
Quantitative Analysis and Clinical Determinants of Orthodontically Induced Root Resorption Using Automated Tooth Segmentation from CBCT Imaging Open
Background Orthodontically induced root resorption (OIRR) is difficult to assess accurately using traditional 2D imaging due to distortion and low sensitivity. While CBCT offers more precise 3D evaluation, manual segmentation remains labor…
View article: H3K14ac facilitates the reinstallation of constitutive heterochromatin in <i>Drosophila</i> early embryos by engaging Eggless/SetDB1
H3K14ac facilitates the reinstallation of constitutive heterochromatin in <i>Drosophila</i> early embryos by engaging Eggless/SetDB1 Open
Constitutive heterochromatin, a fundamental feature of eukaryotic nucleus essential for transposon silencing and genome stability, is rebuilt on various types of repetitive DNA in the zygotic genome during early embryogenesis. However, the…
View article: CityX: Controllable Procedural Content Generation for Unbounded 3D Cities
CityX: Controllable Procedural Content Generation for Unbounded 3D Cities Open
Urban areas, as the primary human habitat in modern civilization, accommodate a broad spectrum of social activities. With the surge of embodied intelligence, recent years have witnessed an increasing presence of physical agents in urban ar…
View article: Semi or fully automatic tooth segmentation in CBCT images: a review
Semi or fully automatic tooth segmentation in CBCT images: a review Open
Cone beam computed tomography (CBCT) is widely employed in modern dentistry, and tooth segmentation constitutes an integral part of the digital workflow based on these imaging data. Previous methodologies rely heavily on manual segmentatio…
View article: SceneX: Procedural Controllable Large-scale Scene Generation
SceneX: Procedural Controllable Large-scale Scene Generation Open
Developing comprehensive explicit world models is crucial for understanding and simulating real-world scenarios. Recently, Procedural Controllable Generation (PCG) has gained significant attention in large-scale scene generation by enablin…
View article: The effect of asymmetric setback of bilateral sagittal split ramus osteotomy on the condyle in patients with skeletal Class III lateral displacement
The effect of asymmetric setback of bilateral sagittal split ramus osteotomy on the condyle in patients with skeletal Class III lateral displacement Open
Objectives The aim of this study was to investigate the postoperative changes of the condyle in patients with skeletal Class III malocclusion and mandibular lateral displacement (MLD), and to study the relationship between asymmetric mandi…
View article: Sodium chloride promotes macrophage pyroptosis and aggravates rheumatoid arthritis by activating SGK1 through GABA receptors Slc6a12
Sodium chloride promotes macrophage pyroptosis and aggravates rheumatoid arthritis by activating SGK1 through GABA receptors Slc6a12 Open
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial inflammation and the production of autoantibodies. Previous studies have indicated an association between high-salt diets (HSD) and an increased r…
View article: Well-posedness and finite-time singularity of solutions in a 4th-order parabolic equation
Well-posedness and finite-time singularity of solutions in a 4th-order parabolic equation Open
This paper deals with a 4th-order parabolic PDE involving $ p $-Laplacian in a bounded domain, subject to Neumann boundary conditions. Firstly, we show the proof of the local existence and uniqueness of weak solutions and the energy identi…
View article: Early Embryonic Establishment of Constitutive Heterochromatin Involves H3K14ac-mediated Recruitment of Eggless/SetDB1
Early Embryonic Establishment of Constitutive Heterochromatin Involves H3K14ac-mediated Recruitment of Eggless/SetDB1 Open
SUMMARY Constitutive heterochromatin, built on various types of repetitive DNA, is a fundamental feature of eukaryotic nucleus essential for transposon silencing and genome stability. However, the molecular programs driving its de novo est…
View article: Targeting fusion proteins of the interleukin family: A promising new strategy for the treatment of autoinflammatory diseases
Targeting fusion proteins of the interleukin family: A promising new strategy for the treatment of autoinflammatory diseases Open
As a means of communication between immune cells and non-immune cells, Interleukins (ILs) has the main functions of stimulating the proliferation and activation of inflammatory immune cells such as dendritic cells and lymphocytes, promote …
View article: Digital working process in diagnosis, treatment planning and fabrication of personalized orthodontic appliances
Digital working process in diagnosis, treatment planning and fabrication of personalized orthodontic appliances Open
Until recently, the working process of personalized orthodontic appliances (POAs) is performed digitally with the use of virtual systems including diagnosis, treatment planning and remote monitoring. Based on the exponential development of…
View article: Analysis of pregnancy outcomes in patients with recurrent implantation failure complicated with chronic endometritis
Analysis of pregnancy outcomes in patients with recurrent implantation failure complicated with chronic endometritis Open
Chronic endometritis (CE) has been considered to reduce uterine receptivity and negatively affect reproductive outcomes for in vitro fertilization-embryo transfer (IVF-ET) patients, especially for people undergoing recurrent implantation f…
View article: Aesthetic Art of Glass Materials in Interior Design
Aesthetic Art of Glass Materials in Interior Design Open
Glass is an ancient and practical material, which has been widely used in interior space design. The development of new glass materials leads to new aesthetic content and cultural connotation. The development of glass materials has become …
View article: Application of Waterscape in Space Environment Design
Application of Waterscape in Space Environment Design Open
Water is the finishing touch in landscape design, and waterscape is the most charming element in the design. In recent years, waterscape has been widely used in space environment design. People living in cities hope to get close to nature …
View article: RETRACTED: Crystal structure of the BAZ2B TAM domain
RETRACTED: Crystal structure of the BAZ2B TAM domain Open
BAZ2B is a regulatory subunit of the ISWI (Imitation Switch) remodeling complex and engages in nucleosome remodeling. Loss-of-function and haploinsufficiency of BAZ2B are associated with different diseases. BAZ2B is a large multidomain pro…
View article: Patient Acceptability of a Novel Technological Solution (Ambient Intelligent Geriatric Management System) to Prevent Falls in Geriatric and General Medicine Wards: A Mixed-Methods Study
Patient Acceptability of a Novel Technological Solution (Ambient Intelligent Geriatric Management System) to Prevent Falls in Geriatric and General Medicine Wards: A Mixed-Methods Study Open
Introduction: As effective interventions to prevent inpatient falls are lacking, a novel technological intervention was trialed. The Ambient Intelligent Geriatric Management (AmbIGeM) system used wearable sensors that detected and alerted …
View article: Structural basis for the recognition of the S2, S5‐phosphorylated RNA polymerase II CTD by the mRNA anti‐terminator protein hSCAF4
Structural basis for the recognition of the S2, S5‐phosphorylated RNA polymerase II CTD by the mRNA anti‐terminator protein hSCAF4 Open
The C‐terminal domain (CTD) of RNA polymerase II serves as a binding platform for numerous enzymes and transcription factors involved in nascent RNA processing and the transcription cycle. The S2, S5‐phosphorylated CTD is recognized by the…