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View article: Engineering the bone metastatic prostate cancer niche through a microphysiological system to report patient-specific treatment response
Engineering the bone metastatic prostate cancer niche through a microphysiological system to report patient-specific treatment response Open
View article: Live Cell Sorting of Differentiated Primary Human Osteoclasts Allows Generation of Transcriptomic Signature Matrix
Live Cell Sorting of Differentiated Primary Human Osteoclasts Allows Generation of Transcriptomic Signature Matrix Open
View article: Integrated analysis of the tumor microenvironment using a reconfigurable microfluidic cell culture platform
Integrated analysis of the tumor microenvironment using a reconfigurable microfluidic cell culture platform Open
The tumor microenvironment (TME) is a complex network of non‐malignant cells and stroma that perform a wide array of vital roles in tumor growth, immune evasion, metastasis, and therapeutic resistance. These highly diverse roles have been …
View article: Advancing Treatment of Bone Metastases through Novel Translational Approaches Targeting the Bone Microenvironment
Advancing Treatment of Bone Metastases through Novel Translational Approaches Targeting the Bone Microenvironment Open
Bone metastases represent a lethal condition that frequently occurs in solid tumors such as prostate, breast, lung, and renal cell carcinomas, and increase the risk of skeletal-related events (SREs) including pain, pathologic fractures, an…
View article: Linking signaling pathways to histone acetylation dynamics in plants
Linking signaling pathways to histone acetylation dynamics in plants Open
As sessile organisms, plants face versatile environmental challenges and require proper responses at multiple levels for survival. Epigenetic modification of DNA and histones is a conserved gene-regulatory mechanism and plays critical role…