Adeline Paris
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View article: H <sub>2</sub> inhalation therapy in patients with moderate COVID-19 (H <sub>2</sub> COVID): a prospective ascending-dose phase I clinical trial
H <sub>2</sub> inhalation therapy in patients with moderate COVID-19 (H <sub>2</sub> COVID): a prospective ascending-dose phase I clinical trial Open
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has triggered a serious global health crisis, resulting in millions of reported deaths since its initial identifi…
View article: H<sub>2</sub>inhalation therapy in patients with moderate Covid 19 (H<sub>2</sub>COVID): a prospective ascending-dose phase 1 clinical trial
H<sub>2</sub>inhalation therapy in patients with moderate Covid 19 (H<sub>2</sub>COVID): a prospective ascending-dose phase 1 clinical trial Open
Introduction The Covid-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has triggered a serious global health crisis, resulting in millions of reported deaths since its initial identification in Chin…
View article: Parents’ decision whether or not to enrol their infant in a clinical trial: towards a patient centred approach? A qualitative study
Parents’ decision whether or not to enrol their infant in a clinical trial: towards a patient centred approach? A qualitative study Open
Background Clinical trials are the cornerstone of drug evaluation but are difficult to perform in children since obtaining written informed consent from both parents is very challenging. We aimed to identify determinants of parents’ decisi…
View article: Effectiveness of a multifaceted intervention to improve interpersonal skills of physicians in medical consultations (EPECREM): protocol for a randomised controlled trial
Effectiveness of a multifaceted intervention to improve interpersonal skills of physicians in medical consultations (EPECREM): protocol for a randomised controlled trial Open
Introduction Interpersonal skills, encompassing communication and empathy, are key components of effective medical consultations. Although many organisations have implemented structured training programmes, limited evidence exists on their…
View article: Incidence of Asymptomatic and Symptomatic Influenza Among Healthcare Workers: A Multicenter Prospective Cohort Study
Incidence of Asymptomatic and Symptomatic Influenza Among Healthcare Workers: A Multicenter Prospective Cohort Study Open
Background Influenza is an important cause of viral hospital-acquired infection involving patients, healthcare workers (HCW), and visitors. The frequency of asymptomatic influenza among HCW with possible subsequent transmission is poorly d…
View article: Population pharmacokinetics of micafungin in ICU patients with sepsis and mechanical ventilation
Population pharmacokinetics of micafungin in ICU patients with sepsis and mechanical ventilation Open
A possible increase in the dose should be evaluated for infections due to C. parapsilosis and for infections due to C. albicans and C. glabrata with MICs ≥0.015 mg/L.
View article: Improved informed consent documents for biomedical research do not increase patients’ understanding but reduce enrolment: a study in real settings
Improved informed consent documents for biomedical research do not increase patients’ understanding but reduce enrolment: a study in real settings Open
Aims The aim was to evaluate the comprehension of participants of an improved informed consent document (ICD). Method This was a randomized controlled French multicentre study performed in real conditions. Participants were adult patients …