Adelyn Crabtree
YOU?
Author Swipe
View article: Effect of Chain Architecture on the Structure, Dynamics, and Rheology of Thermoresponsive Poloxamer Hydrogels and Associated Blends
Effect of Chain Architecture on the Structure, Dynamics, and Rheology of Thermoresponsive Poloxamer Hydrogels and Associated Blends Open
Poloxamers, ABA triblock polymers composed of a poly(propylene oxide) (PPO) midblock (B) and poly(ethylene oxide) (PEO) endblocks (A), are widely studied for biomedical applications. Aqueous poloxamer 407 (P407; also referred to as F127) u…
View article: Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts Open
Poly(ethylene oxide) (PEO) and poloxamers, a class of poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (PEO-PPO-PEO) triblock copolymers, have many personal and medical care applications, including the stabilization of s…
View article: Concentration Threshold for Membrane Protection by PEO–PPO Block Copolymers with Variable Molecular Architectures
Concentration Threshold for Membrane Protection by PEO–PPO Block Copolymers with Variable Molecular Architectures Open
Poloxamer 188, a poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (PEO-PPO-PEO) triblock copolymer, protects cell membranes in several injury models. However, the nature of the copolymer/membrane interaction and the mech…
View article: Synthesis and Micellization of Bottlebrush Poloxamers
Synthesis and Micellization of Bottlebrush Poloxamers Open
Bottlebrush polymers are characterized by an expansive parameter space, including graft length and spacing along the backbone, and these features impact various structural and physical properties such as molecular diffusion and bulk viscos…
View article: Lipid Membrane Binding and Cell Protection Efficacy of Poly(1,2-butylene oxide)-<i>b</i>-poly(ethylene oxide) Copolymers
Lipid Membrane Binding and Cell Protection Efficacy of Poly(1,2-butylene oxide)-<i>b</i>-poly(ethylene oxide) Copolymers Open
Poloxamers consisting of poly(ethylene oxide) (PEO) and poly(propylene oxide) segments can protect cell membranes against various forms of stress. We investigated the role of the hydrophobic block chemistry on polymer/membrane binding and …