Adinda Baten
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View article: Neoadjuvant immune-modulating SBRT and anti-CD73 to increase response to anti-PD-L1 and chemotherapy in early ER+/HER2- breast cancer: primary endpoint and translational results from the randomized Neo-CheckRay trial
Neoadjuvant immune-modulating SBRT and anti-CD73 to increase response to anti-PD-L1 and chemotherapy in early ER+/HER2- breast cancer: primary endpoint and translational results from the randomized Neo-CheckRay trial Open
Patients with oestrogen receptor-positive (ER+), HER2-negative, early breast cancer (BC) have low pathological complete response (pCR) rates following neoadjuvant chemotherapy (NACT). Phase 3 trials showed that adding an anti-PD-1 immune c…
View article: Integrating genetic polymorphisms and clinical data to develop predictive models for skin toxicity in breast cancer radiation therapy
Integrating genetic polymorphisms and clinical data to develop predictive models for skin toxicity in breast cancer radiation therapy Open
Our findings highlight the importance of combining clinical data with genetic markers to enhance the accuracy of models predicting RT toxicity in BC.
View article: Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction
Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction Open
Our results demonstrate that PRS distribution differs even within European ancestry populations leading to underestimation or overestimation of risk in specific European countries, which could potentially influence clinical management of s…
View article: Real-World Pattern-of-Care Analysis of Primary Cutaneous Lymphomas Radiation Therapy Among European Organisation for Research and Treatment of Cancer Members
Real-World Pattern-of-Care Analysis of Primary Cutaneous Lymphomas Radiation Therapy Among European Organisation for Research and Treatment of Cancer Members Open
RT in patients with cutaneous lymphoma is highly heterogeneous among the European Organisation for Research and Treatment of Cancer centers. The development of evidence-based recommendations for RT dose, fractionation, and technique for cu…
View article: Differences in polygenic score distributions in European ancestry populations: implications for breast cancer risk prediction
Differences in polygenic score distributions in European ancestry populations: implications for breast cancer risk prediction Open
The 313-variant polygenic risk score (PRS 313 ) provides a promising tool for breast cancer risk prediction. However, evaluation of the PRS 313 across different European populations which could influence risk estimation has not been perfor…
View article: Exploring the Potential of Combining Non-Coding Rna Polymorphisms and Clinical Data in Predicting Radiotherapy-Induced Toxicity Among Breast Cancer Patients
Exploring the Potential of Combining Non-Coding Rna Polymorphisms and Clinical Data in Predicting Radiotherapy-Induced Toxicity Among Breast Cancer Patients Open
View article: Genome-wide association study of treatment-related toxicity two years following radiotherapy for breast cancer
Genome-wide association study of treatment-related toxicity two years following radiotherapy for breast cancer Open
This GWAS for long-term breast radiation toxicity provides further evidence for significant association of common SNPs with distinct toxicity endpoints.
View article: Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Common variants in breast cancer risk loci predispose to distinct tumor subtypes Open
View article: Additional file 1 of Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Additional file 1 of Common variants in breast cancer risk loci predispose to distinct tumor subtypes Open
Additional file 1. Figures S1 and S2 and Table S1-S4. This file contains supplementary figures 1-2 and supplementary tables 1-4.
View article: Mendelian randomisation study of smoking exposure in relation to breast cancer risk
Mendelian randomisation study of smoking exposure in relation to breast cancer risk Open
View article: Common variants in breast cancer risk loci predispose to distinct tumor subtypes.
Common variants in breast cancer risk loci predispose to distinct tumor subtypes. Open
BACKGROUND: Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate…
View article: Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies? Open
In this study we aim to examine gene–environment interactions (GxEs) between genes involved with estrogen metabolism and environmental factors related to estrogen exposure. GxE analyses were conducted with 1970 Korean breast cancer cases a…