Adithya Sundar
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View article: Formulation and Optimization of Biodegradable Periodontal Chips Containing Metronidazole and Levofloxacin
Formulation and Optimization of Biodegradable Periodontal Chips Containing Metronidazole and Levofloxacin Open
This research aimed to developintrapocket,biodegradablechips ofpoly(d,l-lactide-co-glycolide) (PLGA) loaded with Metronidazole (MZ) and levofloxacin (LF),for sustained release local drug delivery in periodontal pocket to treat periodontiti…
View article: One Health Approach in Investigation of Human Brucellosis: A Case Report and its Investigation
One Health Approach in Investigation of Human Brucellosis: A Case Report and its Investigation Open
Brucellosis is an important zoonotic disease, affecting high-risk occupational groups who are in close contact with animals. This report describes a young field veterinarian who suffered from high fever, night sweat, chills, myalgia, tremo…
View article: Tigecycline : First Member of the Novel Glycylcycline Class of Extended-Spectrum Antibiotics
Tigecycline : First Member of the Novel Glycylcycline Class of Extended-Spectrum Antibiotics Open
Tigecycline is the first member of a synthetic analogue of tetracycline, known as a glycylcyline.Like other tetracyclines, tigecycline is a broad spectrum bacteriostatic agent.It inhibits protein synthesis by binding to the bacterial 30S r…
View article: A Review On Natural Products In Drug Discovery
A Review On Natural Products In Drug Discovery Open
Drug discovery from medicinal plants has evolved to include numerous fields of inquiry and various methods of analysis. The process typically begins with a botanist, ethnobotanist, ethnopharmacologist, or plant ecologist who collects a…
View article: STRUCTURAL AND FUNCTIONAL STUDIES OF CYCLIC K48-LINKED DIUBIQUITIN
STRUCTURAL AND FUNCTIONAL STUDIES OF CYCLIC K48-LINKED DIUBIQUITIN Open
K48-linked di-ubiquitin exists in a dynamic equilibrium between open and closed states. The structure of K48-Ub2 in the closed conformation features a hydrophobic interface formed between the two Ub domains. The same hydrophobic residues a…
View article: Revisiting the susceptibility testing of Mycobacterium tuberculosis to ethionamide in solid culture medium
Revisiting the susceptibility testing of Mycobacterium tuberculosis to ethionamide in solid culture medium Open
Performance parameters at 80 µg/ml breakpoint concentration indicated significant association between PST and MIC methods.