Explanipedia

460 Promotion of Hair Growth in Ex Vivo Human Scalp Hair Follicles by the Novel Ingredient Blend NUL-5: Enhancing Elastin Expression and Wnt Signaling Activation Open

Ilaria Piccini, Ioanna Papasideri, Ashish C. Bhatia, Francisco Campuzano Jiménez, Marta Bertolini · 2025

Hybrid Interval Type-2 Mamdani-TSK Fuzzy System for Regression Analysis Open

Ashish C. Bhatia, Renato Cordeiro de Amorim, Vito De Feo · 2025

Regression analysis is employed to examine and quantify the relationships between input variables and a dependent and continuous output variable. It is widely used for predictive modelling in fields such as finance, healthcare, and enginee…

Safe and effective acne treatment across skin types with a 1726 nm sebum-selective laser: One year data from a prospective multicenter study Open

David S. Goldberg, Salve G. Ronan, Ashish C. Bhatia, Sunil S. Dhawan, Jeremy B. Green , et al. · 2025

The seboselective 1726-nm laser is an effective and well-tolerated therapy for reducing moderate-to-severe facial acne for at least 1 year.

Histologic Study of Abdominal Skin Treated With Mechanical Dermal Micro‐Coring Technology for Minimally Invasive Skin Removal Open

Ashish C. Bhatia, Karl M. Napekoski, Jill Edgecombe, David Weir, Rachelle Winkle , et al. · 2025

Background Mechanical Dermal Micro‐Coring Technology (MCT; Ellacor System) achieves skin tightening and wrinkle reduction through direct mechanical excision of skin cores using hollow needles and collagen stimulation via the wound‐healing …

Consensus Statement on the Prevention and Management of Complications of Fully Ablative Laser Resurfacing of the Face Open

Bianca Y. Kang, Joel L. Cohen, Roy G. Geronemus, Suzanne L. Kilmer, E. Victor Ross , et al. · 2025

Objectives To achieve consensus among expert laser surgeons on standards for the prevention and management of adverse events from fully ablative laser resurfacing of the face. Materials and Methods Delphi study with two rounds of ratings a…

In Vivo and Ex Vivo Evaluation of a Novel Method for Topical Delivery of Macromolecules Through the Stratum Corneum for Cosmetic Applications Open

Ali‐Reza Moradi, Ashish C. Bhatia, Kathleen Behr, Karl M Napekoski, Marianna Földvári · 2024

BACKGROUND Effective topical delivery of large/charged molecules into skin has always been challenging. Chemical penetration enhancers, organic substances that increase permeability of skin, have been in use for decades with variable succe…

Correction: Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression Open

Mengchen Zou, Ashish C. Bhatia, Hangming Dong, Prajisha Jayaprakash, Juchen Guo , et al. · 2024

Following the publication of this article, it was noted that the positive control of MDA-MB-231 cells in Figure 2F (panel v) and a non-specific mutant control of recombinant Hsp90β in Figure 4E (panel h) were mistakenly duplicated with the…

Treatment of mild to severe acne with 1726 nm laser: A safe alternative to traditional acne therapies Open

David J. Goldberg, Anneke Andriessen, Ashish C. Bhatia, Michael H. Gold, Amy B. Lewis , et al. · 2023

Introduction Acne is the most common reason for dermatology consultation in adolescents and young adults. Consultation is often delayed despite unsuccessful self‐treatment. Postponing effective treatment places acne sufferers at higher ris…

Photopneumatic Technology for the Treatment of Mild-to-moderate Acne Vulgaris-Expert Perspectives. Open

Ashish C. Bhatia, Cheryl Burgess, Gilly Munavalli, Jason Smith · 2023

Photopneumatic Technology for the Treatment of Mild-to-moderate Acne Vulgaris-A Review and Expert Perspectives. Open

Ashish C. Bhatia, Cheryl Burgess, Gilly Munavalli, Jason Smith · 2023

Characterization of Tissue Histology for the Injectable Cellulite Treatment Collagenase Clostridium Histolyticum-aaes: Results in Swine Open

Sachin M. Shridharani, Saji Vijayan, Karl M Napekoski, Shannon R. Dalton, Ashish C. Bhatia · 2023

Background Cellulite is a common aesthetic condition that affects predominantly females. Collagenase clostridium histolyticum-aaes (CCH-aaes) injections disrupt native collagen structures, resulting in an improvement in cellulite appearanc…

Real‐world effectiveness and safety of collagenase clostridium histolyticum‐aaes injections for the treatment of thigh cellulite in women: An open‐label study interim analysis Open

John Joseph, Steven Dayan, Ashish C. Bhatia, Sabrina G. Fabi, Sachin M. Shridharani , et al. · 2022

Background Collagenase clostridium histolyticum‐aaes (CCH‐aaes) is approved in the United States for moderate‐to‐severe cellulite in the buttocks of adult women. Aim Interim analysis to evaluate efficacy/safety of CCH‐aaes in the treatment…

Enzymatic Subcision and Remodeling after Collagenase Clostridium histolyticum-Aaes Subcutaneous Injection: Updated Evidence from Porcine and Human Studies Open

Shridharani Sachin, Ashish C. Bhatia, Shannon Dalton, MBBS Saji Vijayan · 2021

BACKGROUND: CCH injection is approved for the treatment of moderate-to-severe cellulite in the buttocks of adult women. Porcine/human studies were conducted to further determine the subdermal impact of CCH, including that on dermal thickne…

Improvements in Submental Contour up to 3 Years After ATX-101: Efficacy and Safety Follow-Up of the Phase 3 REFINE Trials Open

Shannon Humphrey, Joel L. Cohen, Ashish C. Bhatia, Lawrence J. Green, Jeremy B. Green , et al. · 2021

Background ATX-101 (deoxycholic acid) significantly reduced submental fat (SMF) severity in two 24-week Phase 3 studies (REFINE-1 and REFINE-2). Objectives The aim of this study was to evaluate the durability of effect and long-term safety…

Human Pharmacokinetics and Safety of Subcutaneous Collagenase Clostridium Histolyticum in Women Open

Ashish C. Bhatia, Michael McLane, Tony Priestley, Saji Vljyan, Martin K. Gelbard · 2020

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Interdigital Tinea: The Forerunner of Infectious Eczematoid Dermatitis Open

Kyle R Bhatia, Robert T. Brodell, Ashish C. Bhatia, Chelsea S. Mockbee · 2020

Infectious eczematoid dermatitis (IED) is defined as an acute, eczematous eruption that occurs secondary to autosensitization to purulent drainage from a primary infected site. The condition is believed to develop when bacterial products, …

A Consensus on Minimizing the Risk of Hyaluronic Acid Embolic Visual Loss and Suggestions for Immediate Bedside Management Open

Greg Goodman, Mark Magnusson, Peter Callan, Stefania Roberts, Sarah Hart , et al. · 2019

Background Hyaluronic acid fillers have a satisfactory safety profile. However, adverse reactions do occur, and rarely intravascular injection may lead to blindness. Currently there is no internationally recognized consensus on the prevent…

An automated program to find animals and crop photographs for individual recognition Open

Patrick Buehler, Bill Carroll, Ashish C. Bhatia, Vivek Gupta, Derek Lee · 2019

Efficacy of Trifecting<sup>®</sup> Night Cream, a Novel Triple acting Skin Brightening Product: A Double-blind, Placebo-controlled Clinical Study. Open

Lily I. Jiang, Peter Hino, Ashish C. Bhatia, Thomas Stephens, Felipe Piñol Jiménez · 2018

Background: Melasma is a common, persistent disorder of hyperpigmented facial skin predominantly attributed to ultraviolet light exposure, hormonal influences, and genetic predisposition. Objectives: This double-blind, placeb…

Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression Open

Mengchen Zou, Ashish C. Bhatia, Hangming Dong, Priyamvada Jayaprakash, Juchen Guo , et al. · 2016

Both intracellular and extracellular heat shock protein-90 (Hsp90) family proteins (α and β) have been shown to support tumour progression. The tumour-supporting activity of the intracellular Hsp90 is attributed to their N-terminal ATPase-…

Efficacy of Intravenous Magnesium in Facilitating Cardioversion of Atrial Fibrillation Open

Bharath Rajagopalan, Zubair Shah, Deepika Narasimha, Ashish C. Bhatia, Chee H. Kim , et al. · 2016

Background— Low serum magnesium (Mg) levels are associated with an increased risk of atrial fibrillation. Some studies have shown a benefit of Mg in facilitating pharmacological cardioversion. The role of an intravenous infusion of Mg alon…

Active ascertainment of recurrence rate after treatment of primary basal cell carcinoma (BCC) Open

Murad Alam, Shraddha Desai, Michael Nodzenski, Meghan Dubina, Natalie Kim , et al. · 2015

The identification of novel kinase genes associated with androgen independent prostate cancer Open

Ashish C. Bhatia · 2015

Prostate cancer is one of the most common forms of cancer in America affecting one in six men over the age of 65 (Greenlee et al., 2001). When confined to the prostate, surgical removal of the prostate may be curative but when it spreads b…

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