Adjimon Gatien Lokossou
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View article: Maternal Breastfeeding Methods, Breastmilk-Derived Antibodies and Cells Concentrations and Their Impact on Infant Morbidity: Results from a Prospective Cohort in Southern Benin
Maternal Breastfeeding Methods, Breastmilk-Derived Antibodies and Cells Concentrations and Their Impact on Infant Morbidity: Results from a Prospective Cohort in Southern Benin Open
Breastfeeding is associated with long-term well-being including low risks for infectious diseases and non-infectious diseases such as asthma, cancer, autoimmune diseases and obesity during childhood. However, very few studies assessed the …
View article: Human Breast Milk: From Food to Active Immune Response With Disease Protection in Infants and Mothers
Human Breast Milk: From Food to Active Immune Response With Disease Protection in Infants and Mothers Open
Breastfeeding is associated with long-term wellbeing including low risks of infectious diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases and obesity during childhood. In recent years, important advances hav…
View article: Low Serum-Derived Syncytin-2 Levels in Exosome at Early Pregnancy is a Predictor of Preeclampsia: A Prospective Pilot Study in Benin, West Africa
Low Serum-Derived Syncytin-2 Levels in Exosome at Early Pregnancy is a Predictor of Preeclampsia: A Prospective Pilot Study in Benin, West Africa Open
Preeclampsia (PE) affects 2 to 8% of pregnant women and represents one of the major causes of maternal and perinatal morbidity and mortality, particularly in sub-Saharan Africa. A limited number of biomarkers have been proposed for the ide…
View article: Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells†
Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells† Open
Modulation of the activation status of immune cell populations during pregnancy depends on placental villous cytotrophoblast (VCT) cells and the syncytiotrophoblast (STB). Failure in the establishment of this immunoregulatory function lead…
View article: Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin
Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin Open
An arginine-to-histidine replacement at residue 435 in the binding domain of IgG3 to FcRn increases the transplacental transfer and half-life of malaria-specific IgG3 in young infants and is associated with reduced risk of clinical malaria…
View article: siRNA Transfection and EMSA Analyses on Freshly Isolated Human Villous Cytotrophoblasts
siRNA Transfection and EMSA Analyses on Freshly Isolated Human Villous Cytotrophoblasts Open
Human primary villous cytotrophoblasts are a very useful source of primary cells to study placental functions and regulatory mechanisms, and to comprehend diseases related to pregnancy. In this protocol, human primary villous cytotrophobla…