Adny Henrique Silva
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View article: MicroRNA-Mediated Antiproliferative Effects of M1 Macrophage-Derived Extracellular Vesicles on Melanoma Cells
MicroRNA-Mediated Antiproliferative Effects of M1 Macrophage-Derived Extracellular Vesicles on Melanoma Cells Open
Research in tumor treatment has shown promising results using extracellular vesicles (EVs) derived from immune cells. EVs derived from M1 macrophages (proinflammatory), known as M1-EVs, have properties that suppress tumor growth, making th…
View article: Serum from morbidly obese patients affects melanoma cell behavior in vitro
Serum from morbidly obese patients affects melanoma cell behavior in vitro Open
Here we examined whether serum from obese patients could create a growth-enhancing microenvironment that alters gene expression in BRAF- and NRAS-mutated melanoma cell lines. SK-Mel-28 (BRAF-mutated) and Sk-Mel-147 (NRAS-mutated) cells wer…
View article: Blended polymeric films containing the drugs simvastatin and resveratrol: The supersaturation approach for melanoma treatment
Blended polymeric films containing the drugs simvastatin and resveratrol: The supersaturation approach for melanoma treatment Open
In this study, blended films of simvastatin (SIM) and resveratrol (RESV) were developed to improve the release of both poorly soluble drugs, aiming for the topical treatment of melanoma. RESV films containing different plasticizer content …
View article: Three-dimensional multicellular cell culture for anti-melanoma drug screening: focus on tumor microenvironment
Three-dimensional multicellular cell culture for anti-melanoma drug screening: focus on tumor microenvironment Open
View article: MicroRNA profiles in serum samples from Acute-On-Chronic Liver Failure patients and miR-25-3p as a potential biomarker for survival prediction
MicroRNA profiles in serum samples from Acute-On-Chronic Liver Failure patients and miR-25-3p as a potential biomarker for survival prediction Open
View article: Visceral fat increase and signals of inflammation in adipose tissue after administration of titanium dioxide nanoparticles in mice
Visceral fat increase and signals of inflammation in adipose tissue after administration of titanium dioxide nanoparticles in mice Open
Titanium dioxide nanoparticles (TiO 2 NP) are present in several daily use products, and the risks associated with their bioaccumulation must be stablished. Thus, an evaluation of several toxicological-related effects was conducted after i…
View article: Avaliação toxicológica de nanopartículas compostas de dióxido de titânio, superparamagnéticas de óxido de ferro e de poliuretano in vitro, in vivo, ex vivo e in silico
Avaliação toxicológica de nanopartículas compostas de dióxido de titânio, superparamagnéticas de óxido de ferro e de poliuretano in vitro, in vivo, ex vivo e in silico Open
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2015.