Adrian Podoleanu
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Full-field optical coherence tomography system with a simplified dynamic focus mechanism Open
Loss of focus in depth due to the mismatch between the coherence gate and the focus gate is a limiting factor in the achievable high lateral resolution in optical coherence tomography (OCT). This work adapts a simplified dynamic focus meth…
Comprehensive theoretical model for multi-harmonic dispersion-tuned mode-locking (DTML) for use in swept-source OCT Open
In this study, a comprehensive theoretical model for the multi-harmonic dispersion-tuned mode-locking (DTML) regime for swept-source OCT (SS-OCT) is presented for the first time. The principle of wavelength tuning in this regime is describ…
Investigating phototoxicity of optical coherence tomography imaging in porcine and human spermatozoa Open
No significant effect on the kinetics of boar and human spermatozoa was observed following near-infra-red OCT laser radiation. Future work will investigate the fertilization process and embryo development following near-infra-red OCT laser…
Balanced-detection visible optical coherence tomography with a low-noise supercontinuum laser Open
This paper comprehensively demonstrates the efficiency of balanced detection in a visible optical coherence tomography instrument employing a low-noise supercontinuum laser. By using an innovative technique for digitally aligning camera pi…
View article: P-171 Visualisation of embryo morphokinetics using a novel Optical Coherence Tomography Time-Lapse (OCT-TL) system: a pilot study
P-171 Visualisation of embryo morphokinetics using a novel Optical Coherence Tomography Time-Lapse (OCT-TL) system: a pilot study Open
Study question Can OCT-TL effectively help visualise non-invasively cellular dynamics during embryo development? Summary answer OCT-TL offers a non-invasive, 3D visualization technique for detailed embryo imaging and dynamics interpretatio…
Fabrication and testing of lensed fiber-optic probes for distance sensing using common-path low-coherence interferometry Open
Common-path low-coherence interferometry enables high-resolution distance measurements to be made via thin fiber-optic probes. This is particularly advantageous for applications such as ophthalmic vitreoretinal microsurgery, where the prob…
Shot-Noise Limited, 10 MHz Swept-Source Optical Coherence Tomography for Retinal Imaging Open
Akinetic swept-sources are essential for high-speed optical coherence tomography (OCT) imaging. Time-stretched supercontinuum (TSSC) lasers have proven to be efficient for multi-MHz swept-sources. However, lack of low-noise broadband laser…
Shot-noise limited, 10 MHz swept-source optical coherence tomography for retinal imaging Open
Akinetic swept-sources are essential for high-speed optical coherence tomography (OCT) imaging. Time-stretched supercontinuum (TSSC) lasers have proven to be efficient for multi-MHz swept-sources. However, lack of low-noise broadband laser…
Downconversion Master Slave <span>OCT</span> With a Bidirectional Sweeping Laser Open
This paper explores the challenges of signal processing when using optical coherence tomography (OCT) imaging instruments driven by asymmetric MHz bidirectional sweeping lasers. A downconversion master–slave (DMS) method is proposed as a v…
Downconversion master slave optical coherence tomography for simultaneous en-face imaging at two depths Open
We report the production of two en-face optical coherence tomography (OCT) images from two different depths in real time, using three interferometers in a configuration of double downconversion master slave OCT. Two active mixers are used …
Dispersion-Tuned Mode-Locked Laser for Swept Source OCT at 850 nm Using a cFBG and the Pulse Modulation Technique Open
In this paper, the feasibility of employing a fast intensity modulator and a chirped fibre Bragg grating to build a dispersion-tuned mode-locked swept laser (DTML-SS) for OCT at 850 nm is evaluated. Stable mode-locking is achieved by apply…
Spatial distortions in swept source optical coherence tomography due to lateral scanning Open
The paper presents errors in axial distance measurements and deviations of contours in swept source (SS) optical coherence tomography (OCT) cross sections due to lateral scanning. The study shows how these errors and deviations depend on t…
Complex master-slave enhanced optical coherence microscopy Open
We present an instrument designed to facilitate localization and high-resolution, optical coherence microscopy (OCM) imaging of small biological samples immersed in a medium several orders of magnitude greater in volume. A modified turret-…
Complex Master-Slave Enhanced Optical Coherence Microscopy Open
We present an instrument designed to facilitate localization and high-resolution, Optical Coherence Microscopy (OCM) imaging of small biological samples immersed in a medium several orders of magnitude greater in volume. A modified turret-…
Complex Master-Slave Enhanced Optical Coherence Microscopy Open
We present an instrument designed to facilitate localization and high-resolution, Optical Coherence Microscopy (OCM) imaging of small biological samples immersed in a medium several orders of magnitude greater in volume. A modified turret-…
828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser Open
This paper presents a Fourier domain mode locked (FDML) laser centered around 840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of 40 nm. An axial resolution of ∼9.9 µm in water and a 1.4 cm sens…
View article: 30 Years of Optical Coherence Tomography: introduction to the feature issue
30 Years of Optical Coherence Tomography: introduction to the feature issue Open
The guest editors introduce a feature issue commemorating the 30th anniversary of Optical Coherence Tomography.
Temperature Dependence of a Depth-Encoded System for Polarization-Sensitive Optical Coherence Tomography using a PM Fiber Open
A polarization-sensitive optical coherence tomography (PS-OCT) system is able to not only show the structure of samples through the analysis of backscattered light, but is also capable of determining their polarimetric properties. This is …
Development of a 850 nm swept source based on a resonant scanner spectral filter Open
We present a swept source based on a semiconductor optical amplifier (SOA) as a light emitter as well as a gain medium at 850 nm, equipped with a diffraction grating and a 16 kHz resonant scanner. The developed swept source is bidirectiona…
Low-cost speckle reduction method for OCT B-scan imaging Open
The most successful methods for speckle reduction in Optical Coherence Tomography (OCT) are based on deformation of the wavefront used in scanning. Here, a simple method is presented where the wavefront is distorted by lateral translation …
Enhancing the axial resolution of an optoacoustic microscopy imaging instrument by using a pico-second pulse duration laser Open
In conventional optoacoustic microscopy, nanosecond pulse duration lasers are employed. When a laser delivering shorter pulse durations is used, it is expected that, from a theoretical point of view, broader, higher-frequency acoustic wave…
Novel calibration method for optical coherence tomography instruments using multiple spectrometers Open
In this report, a novel calibration method is introduced, which can be used in camera-based optical coherence tomography (OCT) instruments employing several spectrometers. To ensure that all spectrometers are calibrated, i.e. they sense th…
A fully akinetic FDML-like swept source for SS-OCT Open
In this summary, a new, fully akinetic FDML-like or so-called dual resonance sweeping regime for swept source optical coherence tomography, SS-OCT, at 1060 nm is demonstrated. A chirped fiber Bragg grating is used to provide sufficient dis…
View article: P-295 Application of a Time-Lapse Optical Coherence Tomography (OCT) approach in a pilot study to visualise oocytes and embryos in depth
P-295 Application of a Time-Lapse Optical Coherence Tomography (OCT) approach in a pilot study to visualise oocytes and embryos in depth Open
Study question Can we visualise model oocytes and embryos during embryo development using OCT non-invasively? Summary answer This approach, new to embryology, OCT, allows visualising cells in a 3D perspective, providing more detailed infor…
Novel 1.6 MHz swept source for real-time volumetric in-vivo OCT imaging of the human retina Open
In this report, a swept source optical coherence tomography (SS-OCT) instrument, equipped with a novel, multi-MHz tuning range swept source is presented. The source, based on an electrically pumped Micro Electro Mechanical System Vertical …
A dual resonance sweeping regime in dispersion tuned akinetic swept source at 1550 nm Open
In this summary, a fully akinetic FDML-like or so-called dual resonance sweeping regime, for swept source optical coherence tomography, SS-OCT, at 1550 nm is demonstrated. Instead of modulating the optical amplifier gain reported in our pr…
Improvements in Optical Fiber Based Distance Sensor Fabrication for Ophthalmic Micro-Surgery Integration Open
When microsurgery tools are employed in invasive intraocular procedures, the confined space inside the eye represents a patient safety challenge. We propose an integrated fiber sensor, which measures micrometer resolution spacing between t…
Effect of an Anaerobic Fermentation Process on 3D-Printed PLA Materials of a Biogas-Generating Reactor Open
3D-printed materials are present in numerous applications, from medicine to engineering. The aim of this study is to assess their suitability for an application of interest today, that of testing of 3D-printed polylactic acid (PLA)-based r…
40 MHz Swept-Source Optical Coherence Tomography at 1060 nm Using a Time-Stretch and Supercontinuum Spectral Broadening Dynamics Open
We present an akinetically swept light source based on a spectrally broadened mode-locked laser in all normal dispersion optical fiber followed by a linear dispersive time stretch and a regenerative amplification stage. Developed for ultra…
Enhanced resolution optoacoustic microscopy using a picosecond high repetition rate Q-switched microchip laser Open
Conventional optoacoustic microscopy (OAM) instruments have at their core a nanosecond pulse duration laser. If lasers with a shorter pulse duration are used, broader, higher frequency ultrasound waves are expected to be generated and as a…