Adriana Cordova
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View article: Nutritional factors and survival in a cohort of patients with oral cancer
Nutritional factors and survival in a cohort of patients with oral cancer Open
Background Malnutrition commonly affects patients with oral squamous cell carcinoma (OSCC), which contributes to worsening prognosis. Moreover, specific strategies for diagnosing and managing malnutrition in OSCC are lacking. We aimed to i…
View article: Seasonal Change in Microbial Diversity: Bile Microbiota and Antibiotics Resistance in Patients with Bilio-Pancreatic Tumors: A Retrospective Monocentric Study (2010–2020)
Seasonal Change in Microbial Diversity: Bile Microbiota and Antibiotics Resistance in Patients with Bilio-Pancreatic Tumors: A Retrospective Monocentric Study (2010–2020) Open
Background: Bilio-pancreatic tumors are a severe form of cancer with a high rate of associated mortality. These patients showed the presence of bacteria such as Escherichia coli and Pseudomonas spp. in the bile-pancreatic tract. Therefore,…
View article: Microsurgical Reconstruction of Complex Scalp Defects With Vastus Lateralis Free Flap
Microsurgical Reconstruction of Complex Scalp Defects With Vastus Lateralis Free Flap Open
Background Scalp reconstruction is a challenging field for plastic surgeons. In case of large or complex defects, microsurgical‐free flaps are usually required. Reconstructive failure can result in high morbidity and in some cases be life‐…
View article: Partially degalactosylated xyloglucan hydrogel artificial niches enhance human spheroids derived from adipose stem cells stemness and differentiation potential
Partially degalactosylated xyloglucan hydrogel artificial niches enhance human spheroids derived from adipose stem cells stemness and differentiation potential Open
View article: Beyond the Gender Binarism: Neural Correlates of Trans Men in a Functional Connectivity–Resting-State fMRI Pilot Study
Beyond the Gender Binarism: Neural Correlates of Trans Men in a Functional Connectivity–Resting-State fMRI Pilot Study Open
Introduction: Several studies have investigated the specific neural correlates of trans people, highlighting mixed results. This study aimed to compare the presence of specific functional connectivity and differences in cognitive profile a…
View article: Xyloglucan, alginate and k-carrageenan hydrogels on spheroids of adipose stem cells survival; preparation, mechanical characterization, morphological analysis and injectability
Xyloglucan, alginate and k-carrageenan hydrogels on spheroids of adipose stem cells survival; preparation, mechanical characterization, morphological analysis and injectability Open
View article: Characterization of the Secretome from Spheroids of Adipose-Derived Stem Cells (SASCs) and Its Potential for Tissue Regeneration
Characterization of the Secretome from Spheroids of Adipose-Derived Stem Cells (SASCs) and Its Potential for Tissue Regeneration Open
Introduction: Spheroids are spherical aggregates of cells that mimic the three-dimensional (3D) architecture of tissues more closely than traditional two dimensional (2D) cultures. Spheroids of adipose stem cells (SASCs) show special featu…
View article: The “Octopus Head” Dermoglandular Flap: A Novel Technique for Breast Tissue Rearranging after Implant Removal
The “Octopus Head” Dermoglandular Flap: A Novel Technique for Breast Tissue Rearranging after Implant Removal Open
Background: Patients with previous breast augmentation may need implant removal for mechanical complications or other causes. After prosthesis removal, the residual parenchyma can be reshaped through a mastopexy with rearrangement of breas…
View article: Nutritional Factors and Survival in a Cohort of Patients with Oral Cancer
Nutritional Factors and Survival in a Cohort of Patients with Oral Cancer Open
Background: Malnutrition commonly affects patients with oral squamous cell carcinoma (OSCC), which contributes to worsening prognosis. Moreover, specific strategies for diagnosing and managing malnutrition in OSCC are lacking. Methods: Thi…
View article: Nerve Regeneration after a Nerve Graft in a Rat Model: The Effectiveness of Fibrin Glue
Nerve Regeneration after a Nerve Graft in a Rat Model: The Effectiveness of Fibrin Glue Open
Background: Simulating the post-traumatic continuity defect of small human peripheral nerves, we compared the effectiveness of fibrin glue with neurorrhaphy for nerve gap restoration. Methods: In twenty-four male Wistar rats, a fifteen mm …
View article: The wide base bipedicled (WIBB) flap in nipple-sparing skin-reducing mastectomy
The wide base bipedicled (WIBB) flap in nipple-sparing skin-reducing mastectomy Open
In this article, we present a modification of the NS/SRM technique in which the mastopexy design for skin reduction is undertaken with a wide-base bipedicled (WIBB) flap. The WIBB flap can be applied in both autologous and implant-based br…
View article: The Use of Intraoperative Microvascular Doppler in Vascular Neurosurgery: Rationale and Results—A Systematic Review
The Use of Intraoperative Microvascular Doppler in Vascular Neurosurgery: Rationale and Results—A Systematic Review Open
Surgical treatment of neurovascular lesions like intracranial aneurysms, arteriovenous malformations and arteriovenous dural fistulas is still associated with high morbidity. Several recent studies are providing increasing insights into re…
View article: Polymorphous Adenocarcinoma: A Systematic Review of the Literature and Presentation of Two Cases in a Less-Considered Anatomical Site
Polymorphous Adenocarcinoma: A Systematic Review of the Literature and Presentation of Two Cases in a Less-Considered Anatomical Site Open
Background: Polymorphous adenocarcinoma (PAC) is the second-most common malignant tumour of the minor salivary glands. Although PAC predominantly affects the palate, it can also involve the buccal mucosa. This systematic review aims to inv…
View article: Soft tissue reconstruction of the trunk with pedicled perforator and musculocutaneous flaps: A single‐center comparative retrospective study
Soft tissue reconstruction of the trunk with pedicled perforator and musculocutaneous flaps: A single‐center comparative retrospective study Open
Background Soft tissue trunk reconstruction is often challenging. Although free microvascular flaps are a feasible option in case of extensive defects involving deep structures, pedicled flaps represent a good alternative, especially if ha…
View article: Spheroids of adipose derived stem cells show their potential in differentiating towards the angiogenic lineage
Spheroids of adipose derived stem cells show their potential in differentiating towards the angiogenic lineage Open
SASCs, thanks to their multilineage differentiation potential, also possess the ability to differentiate towards endothelial lineage and to organize themselves into angiogenic networks. Moreover, they are able to promote angiogenesis throu…
View article: Implant-Based Breast Reconstruction after Risk-Reducing Mastectomy in BRCA Mutation Carriers: A Single-Center Retrospective Study
Implant-Based Breast Reconstruction after Risk-Reducing Mastectomy in BRCA Mutation Carriers: A Single-Center Retrospective Study Open
Women with BRCA gene mutations have a higher lifetime risk of developing breast cancer. Furthermore, cancer is usually diagnosed at a younger age compared to the wild-type counterpart. Strategies for risk management include intensive surve…
View article: Body mass index and baseline platelet count as predictive factors in Merkel cell carcinoma patients treated with avelumab
Body mass index and baseline platelet count as predictive factors in Merkel cell carcinoma patients treated with avelumab Open
Background Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer, associated with a worse prognosis. The Immune Checkpoint Inhibitors (ICIs) avelumab and pembrolizumab have been recently approved as first-line treatment in metas…
View article: Supplementary Table 1 from Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage
Supplementary Table 1 from Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage Open
Characteristics of patients
View article: Data from Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage
Data from Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage Open
The identification of reciprocal interactions between tumor-infiltrating immune cells and the microenviroment may help us understand mechanisms of tumor growth inhibition or progression. We have assessed the frequencies of tumor-infiltrati…
View article: Supplementary Table 1 from Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage
Supplementary Table 1 from Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage Open
Characteristics of patients
View article: Data from Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage
Data from Squamous Cell Tumors Recruit γδ T Cells Producing either IL17 or IFNγ Depending on the Tumor Stage Open
The identification of reciprocal interactions between tumor-infiltrating immune cells and the microenviroment may help us understand mechanisms of tumor growth inhibition or progression. We have assessed the frequencies of tumor-infiltrati…
View article: Prognostic role of soluble PD-1 and BTN2A1 in overweight melanoma patients treated with nivolumab or pembrolizumab: finding the missing links in the symbiotic immune-metabolic interplay
Prognostic role of soluble PD-1 and BTN2A1 in overweight melanoma patients treated with nivolumab or pembrolizumab: finding the missing links in the symbiotic immune-metabolic interplay Open
Individual response to immune checkpoint inhibitors (ICIs) is currently unpredictable in patients with melanoma. Recent findings highlight a striking improvement in the clinical outcomes of overweight/obese patients treated with ICIs, whic…
View article: Spheroids of Adipose Derived Stem Cells (Sascs) Show Their Potential in Differentiating Towards the Angiogenic Lineage
Spheroids of Adipose Derived Stem Cells (Sascs) Show Their Potential in Differentiating Towards the Angiogenic Lineage Open
View article: Fixation free laparoscopic obliteration of inguinal hernia defects with the 3D dynamic responsive scaffold ProFlor
Fixation free laparoscopic obliteration of inguinal hernia defects with the 3D dynamic responsive scaffold ProFlor Open
View article: Animal models of vascularized nerve grafts: a systematic review
Animal models of vascularized nerve grafts: a systematic review Open
The aim of this review is to present and compare the various animal models of vascularized nerve grafts described in the literature as well as to summarize preclinical evidence for superior functional results compared to non-vascularized f…
View article: Systematic review on spheroids from adipose‐derived stem cells: Spontaneous or artefact state?
Systematic review on spheroids from adipose‐derived stem cells: Spontaneous or artefact state? Open
Three‐dimensional (3D) cell cultures represent the spontaneous state of stem cells with specific gene and protein molecular expression that are more alike the in vivo condition. In vitro two‐dimensional (2D) cell adhesion cultures are stil…
View article: Beyond the Gender Binarism: The Neural Correlates of Trans Men Investigated in a Functional Connectivity–Resting State fMRI Study
Beyond the Gender Binarism: The Neural Correlates of Trans Men Investigated in a Functional Connectivity–Resting State fMRI Study Open
Several studies investigated the specific neural correlates of trans people, highlighting mixed results. This study aimed to investigate the presence of specific functional connectivity in trans men, compared to a homogeneous group of cisg…
View article: The role of sentinel node tumor burden in modeling the prognosis of melanoma patients with positive sentinel node biopsy: an Italian melanoma intergroup study (N = 2,086)
The role of sentinel node tumor burden in modeling the prognosis of melanoma patients with positive sentinel node biopsy: an Italian melanoma intergroup study (N = 2,086) Open
View article: COVID-19 Pandemic And Surgery: An International Study
COVID-19 Pandemic And Surgery: An International Study Open
The GlobalSurg is a project that provides the creation of an international research network in the surgical field, with the aim of producing studies that can improve global health. With the onset of the Covid-19 pandemic, a new platform wa…
View article: Quality life evaluation after mastectomy or Quart
Quality life evaluation after mastectomy or Quart Open
Breast cancer is a worldwide diffused disease and represents the most common tumor among women. Due to great improvements in prevention protocols and imaging, most patients are diagnosticated with non-advanced disease and can either be tre…