Adriana Lucía Vanegas-García
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View article: Azathioprine Hypersensitivity Syndrome Mimicking an Infection in a Systemic Lupus Erythematosus Patient: A Case Report
Azathioprine Hypersensitivity Syndrome Mimicking an Infection in a Systemic Lupus Erythematosus Patient: A Case Report Open
Azathioprine (AZA) is used in clinical practice as a steroid-sparing medication to treat diverse systemic autoimmune diseases, such as inflammatory bowel disease, rheumatoid arthritis, and systemic lupus erythematosus. The adverse effects …
View article: FUNGUS BALL, AN HEMOPTYSIS CAUSE IN A SLE PATIENT
FUNGUS BALL, AN HEMOPTYSIS CAUSE IN A SLE PATIENT Open
PV291 / #290 Case Report Poster Topic: AS17 - Miscellaneous Introduction A fungus ball (mycetoma, aspergilloma) is a conglomeration of fungal hyphae intermingled with mucus and cellular debris, typically found within a pulmonary cavity. Th…
View article: Circulating extracellular vesicles in Systemic Lupus Erythematosus: physicochemical properties and phenotype
Circulating extracellular vesicles in Systemic Lupus Erythematosus: physicochemical properties and phenotype Open
Objective This study aimed to identify the physicochemical and phenotypic characteristics of circulating Extracellular Vesicles (EVs) in the plasma of patients with SLE, with or without Lupus Nephritis (LN), and their potential utility as …
View article: NETosis Secondary to the Use of Levamisole-Adulterated Cocaine: A Likely Underlying Mechanism of Vasculopathy
NETosis Secondary to the Use of Levamisole-Adulterated Cocaine: A Likely Underlying Mechanism of Vasculopathy Open
Background. Since 2010, several cases of a new vasculopathy induced by the use of levamisole-adulterated cocaine (LAC) have been reported. This vasculopathy is characterized by retiform purpura, earlobe necrosis, multisystem compromise, an…
View article: Cardiac involvement in anti-MDA5 dermatomyositis: a case-based review
Cardiac involvement in anti-MDA5 dermatomyositis: a case-based review Open
Among myositis-specific antibodies, anti-melanoma differentiation-associated gene 5 (anti-MDA5) is one of the antibodies with a unique spectrum that is expressed principally in clinically amyopathic dermatomyositis (CADM) and, to a lesser …
View article: Clinical profile of patients with lupus psychosis in a Colombian cohort
Clinical profile of patients with lupus psychosis in a Colombian cohort Open
The objective of this study is to describe the frequency and the clinical, paraclinical, and treatment profile of patients with lupus psychosis in a Colombian cohort of patients with systemic lupus erythematosus (SLE). This retrospective c…
View article: Plasma microparticles from patients with systemic lupus erythematosus modulate the content of miRNAs in U937 cells
Plasma microparticles from patients with systemic lupus erythematosus modulate the content of miRNAs in U937 cells Open
Summary In systemic lupus erythematosus (SLE), the clearance of apoptotic cells and microparticles (MPs) is reduced. Some MPs contain molecules that can modulate immune responses. This study aimed to evaluate the presence of miR‐126 and mi…
View article: Atypical phenotype and response of B cells in patients with seropositive rheumatoid arthritis
Atypical phenotype and response of B cells in patients with seropositive rheumatoid arthritis Open
Summary Patients with rheumatoid arthritis (RA) may be classified as seropositive or seronegative according to the presence of autoantibodies. An abnormal B cell phenotype and function could be one of the main components of the immunopatho…
View article: Induction of NF-κB inflammatory pathway in monocytes by microparticles from patients with systemic lupus erythematosus
Induction of NF-κB inflammatory pathway in monocytes by microparticles from patients with systemic lupus erythematosus Open
The present findings indicate that significant uptake of SLE-MPs by monocytes results in activation, production of inflammatory mediators, and triggering of the NF-κB signaling pathway.
View article: Design of an algorithm for the diagnostic approach of patients with joint pain
Design of an algorithm for the diagnostic approach of patients with joint pain Open
We present an algorithm designed through an international consensus of experts, in which Delphi methodology was used, to support primary care physicians in the clinical approach to patients with joint pain. Key Points • We developed an alg…
View article: Extracellular vesicles are associated with the systemic inflammation of patients with seropositive rheumatoid arthritis
Extracellular vesicles are associated with the systemic inflammation of patients with seropositive rheumatoid arthritis Open
Patients with rheumatoid arthritis (RA) and autoantibodies, such as rheumatoid factor and those against cyclic citrullinated peptides, are designated as seropositive and have a more severe disease with worse prognosis than seronegative RA …
View article: Potential Involvement of Platelet-Derived Microparticles and Microparticles Forming Immune Complexes during Monocyte Activation in Patients with Systemic Lupus Erythematosus
Potential Involvement of Platelet-Derived Microparticles and Microparticles Forming Immune Complexes during Monocyte Activation in Patients with Systemic Lupus Erythematosus Open
Microparticles (MPs) are vesicles derived from the plasma membrane of different cells, are considered a source of circulating autoantigens, and can form immune complexes (MPs-ICs). The number of MPs and MPs-ICs increases in patients with s…
View article: CE-06 Urinary neutrophil gelatinase – associated lipocalin and monocyte chemoattractant protein-1 as biomarkers for lupus nephritis in colombian SLE patients
CE-06 Urinary neutrophil gelatinase – associated lipocalin and monocyte chemoattractant protein-1 as biomarkers for lupus nephritis in colombian SLE patients Open
Background Some previous studies in Caucasian, Asian, and African-American patients have shown that urine levels of Neutrophil Gelatinase–Associated Lipocalin (uNGAL) and Monocyte Chemoattractant Protein-1 (uMCP-1) were significantly great…
View article: Infiltrating CD16<sup>+</sup>Are Associated with a Reduction in Peripheral CD14<sup>+</sup>CD16<sup>++</sup>Monocytes and Severe Forms of Lupus Nephritis
Infiltrating CD16<sup>+</sup>Are Associated with a Reduction in Peripheral CD14<sup>+</sup>CD16<sup>++</sup>Monocytes and Severe Forms of Lupus Nephritis Open
Our aim was to characterize glomerular monocytes (Mo) infiltration and to correlate them with peripheral circulating Mo subsets and severity of lupus nephritis (LN). Methods . We evaluated 48 LN biopsy samples from a referral hospital. Rec…