Adriana Yuriko Koga
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View article: EVALUATION OF HISTOLOGICAL CHANGES IN THE UTERUS OF RATS TREATED WITH ALGINATE FILM CONTAINING 17-Β ESTRADIOL NANOPARTICLES
EVALUATION OF HISTOLOGICAL CHANGES IN THE UTERUS OF RATS TREATED WITH ALGINATE FILM CONTAINING 17-Β ESTRADIOL NANOPARTICLES Open
OBJECTIVE: This study aims to investigate the effect of film containing 17-β estradiol nanoparticles on uterine tissue. The primary focus is on assessing their potential as precise hormonal therapy for skin lesions in oophorectomized rats.…
View article: EVALUATING THE EFFECTIVENESS OF AN INTERNET-BASED TOOL FOR EMOTIONAL ASSESSMENT OF STUDENTS AT A PUBLIC UNIVERSITY IN BRAZIL
EVALUATING THE EFFECTIVENESS OF AN INTERNET-BASED TOOL FOR EMOTIONAL ASSESSMENT OF STUDENTS AT A PUBLIC UNIVERSITY IN BRAZIL Open
University students have a higher prevalence of illnesses that affect their mental health. This leads to a higher risk of dropping out, poor academic performance, drug abuse, difficulties in finding a job after graduation, and suicidal tho…
View article: PREVALENCE OF CHRONIC NON-COMMUNICABLE DISEASES IN A POPULATION DEPRIVED OF LIBERTY IN A STATE PENITENTIARY
PREVALENCE OF CHRONIC NON-COMMUNICABLE DISEASES IN A POPULATION DEPRIVED OF LIBERTY IN A STATE PENITENTIARY Open
Worldwide, the total prison population exceeds 10.7 million people. According to the World Prison Brief, from the Institute for Crime & Justice Policy Research, the United States has the largest prison population in the world, with 1,767,2…
View article: EVALUATING THE EFFECTIVENESS OF AN INTERNET-BASED TOOL FOR EMOTIONAL ASSESSMENT OF STUDENTS AT A PUBLIC UNIVERSITY IN BRAZIL
EVALUATING THE EFFECTIVENESS OF AN INTERNET-BASED TOOL FOR EMOTIONAL ASSESSMENT OF STUDENTS AT A PUBLIC UNIVERSITY IN BRAZIL Open
University students have a higher prevalence of illnesses that affect their mental health. This leads to a higher risk of dropping out, poor academic performance, drug abuse, difficulties in finding a job after graduation, and suicidal tho…
View article: PREVALÊNCIA DE DOENÇAS CRÔNICAS NÃO TRANSMISSÍVEIS EM POPULAÇÃO PRIVADA DE LIBERDADE EM UMA PENITENCIÁRIA ESTADUAL
PREVALÊNCIA DE DOENÇAS CRÔNICAS NÃO TRANSMISSÍVEIS EM POPULAÇÃO PRIVADA DE LIBERDADE EM UMA PENITENCIÁRIA ESTADUAL Open
Worldwide, the total prison population exceeds 10.7 million people. According to the World Prison Brief, from the Institute for Crime & Justice Policy Research, the United States has the largest prison population in the world, with 1,767,2…
View article: EVALUATION OF HISTOLOGICAL CHANGES IN THE UTERUS OF RATS TREATED WITH ALGINATE FILM CONTAINING 17-Β ESTRADIOL NANOPARTICLES
EVALUATION OF HISTOLOGICAL CHANGES IN THE UTERUS OF RATS TREATED WITH ALGINATE FILM CONTAINING 17-Β ESTRADIOL NANOPARTICLES Open
OBJECTIVE: This study aims to investigate the effect of film containing 17-β estradiol nanoparticles on uterine tissue. The primary focus is on assessing their potential as precise hormonal therapy for skin lesions in oophorectomized rats.…
View article: Topical Application of Estrogen Nanocapsules on Skin Incision Improves Fracture Healing in Osteoporotic Rats
Topical Application of Estrogen Nanocapsules on Skin Incision Improves Fracture Healing in Osteoporotic Rats Open
Objective The challenge of consolidating osteoporotic fractures, particularly exacerbated by postmenopausal estrogen deficiency, underscores the urgent need for effective interventions. This study aims to evaluate the impact of locally adm…
View article: The Inflammatory Reaction to Silicone Implants: Polyurethane Foam Versus Nanotextured Surface—An Experimental Study in Rats
The Inflammatory Reaction to Silicone Implants: Polyurethane Foam Versus Nanotextured Surface—An Experimental Study in Rats Open
Background: The interaction between the surface of the implant and the human body results in a local and systemic inflammatory reaction that leads to the formation of a peri-implant capsule and entails complications. This study aimed to ev…
View article: The use of surgical glue and sutures in the aponeurosis synthesis of the abdominal wall in Wistar rats.
The use of surgical glue and sutures in the aponeurosis synthesis of the abdominal wall in Wistar rats. Open
The synthesis of the abdominal aponeurosis performed with surgical glue (2-octyl cyanoacrylate) showed adequate resistance to rupture tension to maintain its integrity when compared with the synthesis with polypropylene thread or poligleca…
View article: Effects of curcumin supplementation on the severity of intra-abdominal adhesions in rats
Effects of curcumin supplementation on the severity of intra-abdominal adhesions in rats Open
Purpose: To evaluate the effect of curcumin administered by gavage, on reducing intra-abdominal adhesions and attenuating the inflammatory process, assessed by a serum marker. Methods: Forty Wistar rats were randomly divided into two group…
View article: 64. The Inflammatory Reaction To Silicone Implants: Polyurethane Foam Vs Nanotextured Surface. An Experimental Study In Rats
64. The Inflammatory Reaction To Silicone Implants: Polyurethane Foam Vs Nanotextured Surface. An Experimental Study In Rats Open
Purpose: The interaction between the surface of the implant and the human body results in a local and systemic inflammatory reaction that leads to the formation of a peri-implant capsule and entails complications like contractures, calcifi…
View article: Integrative analysis on the effects of streptozotocin in the experimental model for diabetization in wistar rats: histological and laboratory study
Integrative analysis on the effects of streptozotocin in the experimental model for diabetization in wistar rats: histological and laboratory study Open
The study of complications of diabetes mellitus is important to understand the alterations on the specific tissues affected by this chronic disease. An animal model that simulated this complication is necessary for further treatments and p…
View article: Effects of curcumin supplementation on abdominal surgical wound healing
Effects of curcumin supplementation on abdominal surgical wound healing Open
Curcumin supplementation was able to significantly reduce inflammatory parameters in both pre-and post-operative phases of abdominal surgical wounds in rats.
View article: Calendula glycolic extract enhances wound healing of alginate hydrogel
Calendula glycolic extract enhances wound healing of alginate hydrogel Open
These findings evidenced the therapeutic potential of combining calendula extract and alginate for promoting enhanced wound healing.
View article: Effects of Replacing Inorganic with Organic Glycinates Trace Minerals on Growth Performance, Gut Function, and Minerals Loss of Juvenile Nile Tilapia
Effects of Replacing Inorganic with Organic Glycinates Trace Minerals on Growth Performance, Gut Function, and Minerals Loss of Juvenile Nile Tilapia Open
This study aimed to investigate the effects of replacing inorganic trace minerals (ITM) with organic trace minerals (OTM) on growth performance, body composition, gut histomorphometry, digestive enzyme activity, apparent digestibility coef…
View article: Preliminary Evaluation of Wound Healing Potential of<i>Leonurus japonicus</i>Houtt. Extracts
Preliminary Evaluation of Wound Healing Potential of<i>Leonurus japonicus</i>Houtt. Extracts Open
Leonurus japonicus Houtt. is a medicinal plant popular in Brazil as “rubim”, used in local folk medicine for several applications as an anti‐inflammatory, antioxidant, analgesic, and antimicrobial phytomedicine. The traditional use for wou…
View article: Preclinical Trial of <i>Ocotea puberula</i> (Rich.) Nees (“Canela‐Guaicá”) in Wound Healing: Validation of a Traditional Medicine Practice Used by Indigenous Groups in Southern Brazil
Preclinical Trial of <i>Ocotea puberula</i> (Rich.) Nees (“Canela‐Guaicá”) in Wound Healing: Validation of a Traditional Medicine Practice Used by Indigenous Groups in Southern Brazil Open
Background . “Canela‐guaicá,” “guaicá,” or “canela‐sebo” [ Ocotea puberula (Rich.) Nees] is a native species that is traditionally used by Kaingang indigenous groups for wound healing in southern Brazil. The aim of this study was to extrac…
View article: Cilostazol protects against changes caused by streptozotocin-induced diabetic retinopathy
Cilostazol protects against changes caused by streptozotocin-induced diabetic retinopathy Open
By decreasing the loss of ganglion cells and reducing the sensorineural atrophy in the internal retinal layers, cilostazol had a protective effect against changes caused by diabetic retinopathy in diabetic rats.
View article: Cilostazol protects against changes caused by streptozotocin-induced diabetic retinopathy
Cilostazol protects against changes caused by streptozotocin-induced diabetic retinopathy Open
Purpose: This study investigates the protective effect of cilostazol on the development and evolution of diabetic retinopathy in rats. Methods: Sixty male rats were divided into four groups: untreated nondiabetic rats, untreated diabetic r…
View article: THE USE OF SURGICAL ADHESIVE AND SUTURE FIXING MESHES TO THE ABDOMINAL WALL: AN EXPERIMENTAL STUDY IN RATS
THE USE OF SURGICAL ADHESIVE AND SUTURE FIXING MESHES TO THE ABDOMINAL WALL: AN EXPERIMENTAL STUDY IN RATS Open
- BACKGROUND: Proper fixation of the surgical mesh determines the success of a herniorrhaphy. Understanding the inflammatory response and the mechanical properties of the mesh helps to define whether a fixation method is superior. AIM: Thi…
View article: THE USE OF SURGICAL ADHESIVE AND SUTURE FIXING MESHES TO THE ABDOMINAL WALL: AN EXPERIMENTAL STUDY IN RATS
THE USE OF SURGICAL ADHESIVE AND SUTURE FIXING MESHES TO THE ABDOMINAL WALL: AN EXPERIMENTAL STUDY IN RATS Open
- BACKGROUND: Proper fixation of the surgical mesh determines the success of a herniorrhaphy. Understanding the inflammatory response and the mechanical properties of the mesh helps to define whether a fixation method is superior. AIM: Thi…
View article: Characterization and In Vitro and In Vivo Evaluation of Tacrolimus-Loaded Poly(ε-Caprolactone) Nanocapsules for the Management of Atopic Dermatitis
Characterization and In Vitro and In Vivo Evaluation of Tacrolimus-Loaded Poly(ε-Caprolactone) Nanocapsules for the Management of Atopic Dermatitis Open
Background: Tacrolimus (TAC) is a drug of natural origin used in conventional topical dosage forms to control atopic dermatitis. However, direct application of the drug often causes adverse side effects in some patients. Hence, drug nanoen…
View article: DEVELOPMENT AND VALIDATION OF AN HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE DETERMINATION OF 17-Β ESTRADIOL IN POLYMERIC NANOPARTICLES
DEVELOPMENT AND VALIDATION OF AN HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE DETERMINATION OF 17-Β ESTRADIOL IN POLYMERIC NANOPARTICLES Open
Objective: A simple high-performace liquid chromatography method was developed and validated to determine 17-β estradiol in poly (ε-caprolactone) nanocapsules.
Methods: The chromatographic conditions were as follows: C18 GL column with a …
View article: Evaluation of wound healing effect of alginate film containing Aloe vera gel and cross-linked with zinc chloride
Evaluation of wound healing effect of alginate film containing Aloe vera gel and cross-linked with zinc chloride Open
Purpose To develop a new wound dressing composed of alginate and Aloe vera gel and cross-linked with zinc ions. Methods The aloe-alginate film was characterized using scanning electron microscopy (SEM), swelling profile, mechanical propert…
View article: Evaluation of blood biomarkers in rats submitted to nanotextured and polyurethane foam-coated silicone implants
Evaluation of blood biomarkers in rats submitted to nanotextured and polyurethane foam-coated silicone implants Open
RESUMO Introdução: Nas últimas décadas houve uma grande evolução na superfície de revestimento dos implantes mamários, o que resultou na diminuição das complicações. No pós-operatório a inflamação é uma constante e pode ser avaliada pelo h…
View article: Evaluation of protein adsorption in rats submitted to nanotextured and polyurethane foam-coated silicone mini-implants
Evaluation of protein adsorption in rats submitted to nanotextured and polyurethane foam-coated silicone mini-implants Open
RESUMO Introdução: O controle da absorção de proteínas é necessário para a definição das propriedades dos biomateriais e de seus usos específicos. O plasma sanguíneo contém diversas proteínas diferentes, dentre elas o fibrinogênio, que apr…
View article: DEVELOPMENT AND VALIDATION OF A FAST AND SENSITIVE UHPLC-PDA METHOD FOR THE QUANTIFICATION OF URSOLIC ACID IN POLY(L-LACTIC ACID) NANOCAPSULES
DEVELOPMENT AND VALIDATION OF A FAST AND SENSITIVE UHPLC-PDA METHOD FOR THE QUANTIFICATION OF URSOLIC ACID IN POLY(L-LACTIC ACID) NANOCAPSULES Open
Objective: The aim of the present study is to develop and validation of a ultra-high performance liquid chromatography (UHPLC) method to determine the ursolic acid content and its encapsulation efficiency (EE) in lipid-core nanocapsules pr…
View article: Evaluation of wound healing effect of alginate film containing Aloe vera gel and cross-linked with zinc chloride
Evaluation of wound healing effect of alginate film containing Aloe vera gel and cross-linked with zinc chloride Open
The aloe-alginate film showed adequate physicochemical characteristics for wound dressing applications. The in vivo assay demonstrated that aloe-alginate film enhanced the healing process of incisional skin wounds.
View article: Several aspects of Zingiber zerumbet: a review
Several aspects of Zingiber zerumbet: a review Open
Zingiber zerumbet (L.) Roscoe ex Sm., Zingiberaceae, is a perennial, aromatic and tuberose plant that grows in humid locations. Also known as bitter ginger, Z. zerumbet is traditionally found throughout Asia, where it is widely used in foo…