Adrienne C. DeBrosse
YOU?
Author Swipe
View article: Development of a Novel Benzodiazepine to Delineate Peripheral GABA-A Signaling Mechanisms in Visceral Pain Syndromes
Development of a Novel Benzodiazepine to Delineate Peripheral GABA-A Signaling Mechanisms in Visceral Pain Syndromes Open
Background and Aims Visceral pain is a cardinal symptom of many disorders affecting the gut. Modulators of gamma-aminobutyric acid (GABA) such as benzodiazepines may attenuate colonic pain but the specific contribution of peripheral GABAA …
View article: Degrading stimuli by reducing image resolution impairs performance in a rodent continuous performance test
Degrading stimuli by reducing image resolution impairs performance in a rodent continuous performance test Open
View article: Electrophysiological correlates of attention in the locus coeruleus–prelimbic cortex circuit during the rodent continuous performance test
Electrophysiological correlates of attention in the locus coeruleus–prelimbic cortex circuit during the rodent continuous performance test Open
View article: Electrophysiological correlates of attention in the locus coeruleus - anterior cingulate cortex circuit during the rodent continuous performance test
Electrophysiological correlates of attention in the locus coeruleus - anterior cingulate cortex circuit during the rodent continuous performance test Open
Sustained attention, the ability to focus on an activity or stimulus over time, is significantly impaired in many psychiatric disorders, and there remains a major unmet need in treating impaired attention. Continuous performance tests (CPT…
View article: Stimulus degradation impairs performance in a rodent continuous performance test
Stimulus degradation impairs performance in a rodent continuous performance test Open
Sustained attention is a core cognitive domain that is often disrupted in neuropsychiatric disorders. Continuous performance tests (CPTs) are the most common clinical assay of sustained attention. In CPTs, participants produce a behavioral…
View article: Inhibition of Catechol-O-methyltransferase Does Not Alter Effort-Related Choice Behavior in a Fixed Ratio/Concurrent Chow Task in Male Mice
Inhibition of Catechol-O-methyltransferase Does Not Alter Effort-Related Choice Behavior in a Fixed Ratio/Concurrent Chow Task in Male Mice Open
Effort-related choice (ERC) tasks allow animals to choose between high-value reinforcers that require high effort to obtain and low-value/low-effort reinforcers. Dopaminergic neuromodulation regulates ERC behavior. The enzyme catechol-O…
View article: Effects of catechol-<i>O</i>-methyltransferase inhibition on effort-related choice behavior in male mice
Effects of catechol-<i>O</i>-methyltransferase inhibition on effort-related choice behavior in male mice Open
Effort-related choice (ERC) tasks allow animals to choose between high-value reinforcers that require high effort to obtain or low-value/low-effort reinforcers. Dopaminergic neuromodulation regulates effort-related choice behavior. The enz…