Adrijana Gombosev
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View article: Effectiveness of a local recruitment registry in older adults in Southern California
Effectiveness of a local recruitment registry in older adults in Southern California Open
Background Despite their potential as tools for improving the efficiency of accrual in clinical research, few analyses have assessed the effectiveness of recruitment registries. We investigated referrals to clinical research studies from t…
View article: Effectiveness of a Local Recruitment Registry
Effectiveness of a Local Recruitment Registry Open
Background Recruitment registries are tools to decrease the time and cost required to identify and enroll eligible participants into clinical research. Despite their potential to increase the efficiency of accrual, few analyses have assess…
View article: Chlorhexidine and Mupirocin for Clearance of Methicillin-Resistant <i>Staphylococcus aureus</i> Colonization After Hospital Discharge: A Secondary Analysis of the Changing Lives by Eradicating Antibiotic Resistance Trial
Chlorhexidine and Mupirocin for Clearance of Methicillin-Resistant <i>Staphylococcus aureus</i> Colonization After Hospital Discharge: A Secondary Analysis of the Changing Lives by Eradicating Antibiotic Resistance Trial Open
Background The CLEAR Trial demonstrated that a multisite body decolonization regimen reduced post-discharge infection and hospitalization in methicillin-resistant Staphylococcus aureus (MRSA) carriers. Here, we describe decolonization effi…
View article: Adolescent COVID-19 Vaccine Decision-Making among Parents in Southern California
Adolescent COVID-19 Vaccine Decision-Making among Parents in Southern California Open
Adolescent COVID-19 vaccination has stalled at 53% in the United States. Vaccinating adolescents remains critical to preventing the continued transmission of COVID-19, the emergence of variants, and rare but serious disease in children, an…
View article: Direct Mail Recruitment to a Potential Participant Registry
Direct Mail Recruitment to a Potential Participant Registry Open
Recruitment registries are novel tools to accelerate Alzheimer disease research accrual. Optimal methods to populate such registries remain largely unstudied. We sent postcards with 3 unique taglines (Alzheimer’s Prevention Research, brain…
View article: Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers
Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers Open
Postdischarge MRSA decolonization with chlorhexidine and mupirocin led to a 30% lower risk of MRSA infection than education alone. (Funded by the AHRQ Healthcare-Associated Infections Program and others; ClinicalTrials.gov number, NCT01209…
View article: Chlorhexidine Versus Routine Bathing to Prevent Multi Drug-Resistant Organisms and All-Cause Bloodstream Infection in General Medical and Surgical Units: The ABATE Infection Cluster Randomized Trial
Chlorhexidine Versus Routine Bathing to Prevent Multi Drug-Resistant Organisms and All-Cause Bloodstream Infection in General Medical and Surgical Units: The ABATE Infection Cluster Randomized Trial Open
View article: Emergence of carbapenem-resistant Enterobacteriaceae in Orange County, California, and support for early regional strategies to limit spread
Emergence of carbapenem-resistant Enterobacteriaceae in Orange County, California, and support for early regional strategies to limit spread Open
View article: Consent-to-Contact Registry: A New Tool for Accelerating Clinical Research Recruitment at UCI
Consent-to-Contact Registry: A New Tool for Accelerating Clinical Research Recruitment at UCI Open
C-2-C, UCI MIND, and ICTS Translational Science Research Day 2017, University of California Irvine\n  \n Introduction: The most consistent barrier to improved medical care is slow recruitment to clinical research. To help clinical investi…
View article: Daily Chlorhexidine Bathing in General Hospital Units – Results of the ABATE Infection Trial (Active BAThing to Eliminate Infection)
Daily Chlorhexidine Bathing in General Hospital Units – Results of the ABATE Infection Trial (Active BAThing to Eliminate Infection) Open
Background Universal decolonization with daily chlorhexidine (CHG) bathing with and without nasal decolonization has significantly reduced positive MRSA clinical cultures and bloodstream infections in adult ICUs in several clinical trials.…
View article: Randomized Double-Blinded Placebo-Controlled Trial to Assess the Effect of Retapamulin for Nasal Decolonization of Mupirocin-Resistant Methicillin-Resistant Staphylococcus aureus Nasal Carriers
Randomized Double-Blinded Placebo-Controlled Trial to Assess the Effect of Retapamulin for Nasal Decolonization of Mupirocin-Resistant Methicillin-Resistant Staphylococcus aureus Nasal Carriers Open
View article: Project CLEAR (Changing Lives by Eradicating Antibiotic Resistance) Randomized Controlled Trial (RCT): Serial Decolonization of Recently Hospitalized Methicillin-Resistant Staphylococcus aureus (MRSA) Carriers Reduces Risks of MRSA Infections and All-Cause Infections in the 1-Year Post-Hospitalization
Project CLEAR (Changing Lives by Eradicating Antibiotic Resistance) Randomized Controlled Trial (RCT): Serial Decolonization of Recently Hospitalized Methicillin-Resistant Staphylococcus aureus (MRSA) Carriers Reduces Risks of MRSA Infections and All-Cause Infections in the 1-Year Post-Hospitalization Open
View article: Reduction of MDRO Colonization in Nursing Home Residents with Routine Use of Chlorhexidine Bathing and Nasal Iodophor (Project PROTECT)
Reduction of MDRO Colonization in Nursing Home Residents with Routine Use of Chlorhexidine Bathing and Nasal Iodophor (Project PROTECT) Open
View article: Oversight on the borderline: Quality improvement and pragmatic research
Oversight on the borderline: Quality improvement and pragmatic research Open
Pragmatic research that compares interventions to improve the organization and delivery of health care may overlap, in both goals and methods, with quality improvement activities. When activities have attributes of both research and qualit…