Aert F. Scheper
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View article: Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism
Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism Open
Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP), a significant global health burden. While glycosylation plays a key role in cellular signaling and inflammation, its role in IVD degeneration remains poorly un…
View article: Unravelling the glycome in human intervertebral disc degeneration: Aberrant glycosylation modulates inflammation and metabolism
Unravelling the glycome in human intervertebral disc degeneration: Aberrant glycosylation modulates inflammation and metabolism Open
Intervertebral disc (IVD) degeneration is one of the major contributing causes of low back pain (LBP), a common health issue that imposes a significant socio-economic burden on society. Previous work has demonstrated a dysregulated glycome…
View article: Understanding glycosylation: Regulation through the metabolic flux of precursor pathways
Understanding glycosylation: Regulation through the metabolic flux of precursor pathways Open
Glycosylation is how proteins and lipids are modified with complex carbohydrates known as glycans. The posttranslational modification of proteins with glycans is not a template-driven process in the same way as genetic transcription or pro…
View article: Understanding glycosylation: Regulation through the metabolic flux of precursor pathways
Understanding glycosylation: Regulation through the metabolic flux of precursor pathways Open
Glycosylation is how proteins and lipids are modified with complex carbohydrates known as glycans. The post-translational modification of proteins with glycans is not a template-driven process in the same way as genetic transcription or pr…