Explanipedia

Guideline-Directed Medical Therapy in Pregnancy and Lactation: Navigating Evidence Gaps and Clinical Application Open

Karlee Hoffman, Julia Simkowski, Afshan B. Hameed, Ashten Waks, Kathleen Faulkenberg , et al. · 2025

A Parturient With Fontan Physiology and Suspected Placenta Accreta Spectrum: A Case Report Open

Taizoon Q Dhoon, Benjamin Rosellini, Michael Holland, Josh N. Vo, Yeyoon Choi , et al. · 2025

This manuscript reviews a complex case of a gravida 3, para 2 (G3P2) parturient with Fontan physiology, complicated by suspected placenta accreta spectrum (PAS) versus massive subchorionic thrombohematoma (MST), presenting with placental a…

Investigation of Using Non-Contact Electrodes for Fetal ECG Monitoring Open

Tai Van Le, Hoàng Trúc Lưu, Loan Pham-Nguyen, Hung Viet-Dao, Duc Nguyen Minh , et al. · 2025

Regular physiological monitoring of maternal and fetal parameters is indispensable for ensuring safe outcomes during pregnancy and parturition. Fetal electrocardiogram (fECG) assessment is crucial to detect fetal distress and developmental…

Patient Experiences and Behavioral Changes Following Cardiovascular Risk Assessment During Pregnancy and Postpartum Open

Kerly M. Guerrero, Diana Wolfe, Afshan B. Hameed, Heike Thiel de Bocanegra · 2025

Cardiovascular disease (CVD) is the leading cause of maternal mortality in the United States. Two major hospital networks implemented a novel CVD risk assessment of pregnant and postpartum patients to standardize identification of patients…

Neighborhood Disinvestment and Racial and Ethnic Disparities in Peripartum Cardiomyopathy in California, From 2004 to 2019 Open

Curisa M. Tucker, Chen Ma, Mahasin S. Mujahid, Afshan B. Hameed, Audrey Lyndon , et al. · 2025

Background Peripartum cardiomyopathy (PPCM) is a rare medical condition presenting as idiopathic heart failure. The aim of this study was to (1) examine the contribution of neighborhood disinvestment to PPCM risk and to racial and ethnic d…

Results of cardiovascular testing among pregnant and postpartum persons undergoing standardized cardiovascular risk assessment Open

Afshan B. Hameed, Maryam Tarsa, Ashten Waks, Anna Grodzinsky, Karen Florio , et al. · 2025

Implementing a standardized CVD Risk Assessment algorithm may enhance the detection of cardiovascular disease in pregnant and postpartum patients with previously unknown CVD or at risk of developing CVD, providing a valuable tool that comp…

CVD Case Series: Screening and Risk Reduction Open

Ruth Woldemichael, Cornelia Graves, Afshan B. Hameed · 2024

Undetected cardiovascular disease is one of the leading causes of complications during pregnancy in the United States. Maternal mortality reviews indicate that lack of suspicion and delays in diagnosis are the primary drivers of CVD-relate…

CVD Case Series: Screening and Risk Reduction Open

Ruth Woldemichael, Cornelia Graves, Afshan B. Hameed · 2024

Undetected cardiovascular disease is one of the leading causes of complications during pregnancy in the United States. Maternal mortality reviews indicate that lack of suspicion and delays in diagnosis are the primary drivers of CVD-relate…

Universal Cardiovascular Disease Risk Assessment in Pregnancy Open

Afshan B. Hameed, Maryam Tarsa, Cornelia Graves, Anna Grodzinsky, Heike Thiel de Bocanegra , et al. · 2024

The United States has the highest maternal mortality rate among developed countries, with cardiovascular disease (CVD) being one of the leading causes of maternal deaths. Diagnosing CVD during pregnancy may be challenging as symptoms of no…

Bicoastal Spontaneous Coronary Artery Dissection: A Therapeutic Dilemma Open

A. Pham, Madushka Y. De Zoysa, Brian Ghoshhajra, Nandita S. Scott, Afshan B. Hameed · 2024

Due to the potential for severe maternal morbidity and even mortality, pregnancy-associated spontaneous coronary artery dissection (P-SCAD) often presents as a clinical conundrum. While current recommendations encourage coronary interventi…

466 EKG/ECHO findings among Black patients with positive cardiovascular risk assessment during pregnancy and postpartum Open

Kerly M. Guerrero, Ariana Banuelos, Avish Arora, Kevin Flatley, Heike Thiel de Bocanegra , et al. · 2024

Intrapartum Management in Maternal Brugada Syndrome Open

Helena Y. Hong, Gina F. Milone, Jaber J. Hanhan, Brittany File, Afshan B. Hameed · 2023

Brugada syndrome is a genetic cardiac disease associated with increased risk of ventricular tachyarrhythmia and sudden cardiac arrest. Labor and delivery in this population poses management challenges of labor induction, analgesia, postpar…

Assessment and Prediction of Cardiovascular Contributions to Severe Maternal Morbidity Open

Aarti Thakkar, Afshan B. Hameed, Minhal Makshood, Brent Gudenkauf, Andreea A. Creanga , et al. · 2023

Severe maternal morbidity (SMM) refers to any unexpected outcome directly related to pregnancy and childbirth that results in both short-term delivery complications and long-term consequences to a women's health. This affects about 60,000 …

Alliance for Innovation on Maternal Health Open

Afshan B. Hameed, Alison J. Haddock, Diana Wolfe, Karen Florio, Nora Drummond , et al. · 2023

Cardiac conditions are the leading cause of pregnancy-related deaths and disproportionately affect non-Hispanic Black people. Multidisciplinary maternal mortality review committees have found that most people who died from cardiac conditio…

Cardiovascular Risk Assessment as a Quality Measure in the Pregnancy and Postpartum Period Open

Afshan B. Hameed, Maryam Tarsa, Cornelia Graves, Jenny Chang, Manija Billah , et al. · 2023

ERα/ERβ-directed CBS transcription mediates E2β-stimulated hUAEC H2S production Open

Jin Bai, Thomas J. Lechuga, Joshua Makhoul, Hao Yan, Carol Major , et al. · 2022

Elevated endogenous estrogens stimulate human uterine artery endothelial cell (hUAEC) hydrogen sulfide (H 2 S) production by selectively upregulating the expression of H 2 S synthesizing enzyme cystathionine β-synthase (CBS), but the under…

The Utilization and Interpretation of Cardiac Biomarkers During Pregnancy Open

Amy Sarma, Niti R. Aggarwal, Joan Briller, Melinda B. Davis, Katherine E. Economy , et al. · 2022

Cardiovascular Complications of Pregnancy-Associated COVID-19 Infections Open

Joan Briller, Niti R. Aggarwal, Melinda B. Davis, Afshan B. Hameed, Isabelle Malhamé , et al. · 2022

Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter Open

Sadaf Sarafan, Tai Le, Michael Lau, Afshan B. Hameed, Tadesse Ghirmai , et al. · 2022

Fetal electrocardiogram (fECG) assessment is essential throughout pregnancy to monitor the wellbeing and development of the fetus, and to possibly diagnose potential congenital heart defects. Due to the high noise incorporated in the abdom…

Screening for Cardiovascular Disease in Pregnancy: Is There a Need? Open

Melissa E. Chambers, Madushka Y. De Zoysa, Afshan B. Hameed · 2022

Maternal mortality in the United States has been on the rise. Every year, about 700 women die from pregnancy-related complications. Cardiovascular disease (CVD) accounts for a large majority of pregnancy-related deaths driven by the lack o…

Is the Placenta Inflamed in Cardiovascular Disease? Open

Afshan B. Hameed, Ernesto González Licón · 2022

[Figure: see text]

Call to Action: Maternal Health and Saving Mothers: A Policy Statement From the American Heart Association Open

Laxmi S. Mehta, Garima Sharma, Andreea A. Creanga, Afshan B. Hameed, Lisa M. Hollier , et al. · 2021

The United States has the highest maternal mortality rates among developed countries, and cardiovascular disease is the leading cause. Therefore, the American Heart Association has a unique role in advocating for efforts to improve materna…

Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter Open

Sadaf Sarafan, Tai Le, Michael Lau, Afshan B. Hameed, Tadesse Ghirmai , et al. · 2021

Fetal electrocardiogram (fECG) assessment is essential throughout pregnancy to monitor the wellbeing and development of the fetus, and to possibly diagnose potential congenital heart defects. Due to the high noise incorporated in the abdom…

Characteristics and Outcomes of Women With COVID-19 Giving Birth at US Academic Centers During the COVID-19 Pandemic Open

Justine Chinn, Shaina Sedighim, Katharine A. Kirby, Samuel F. Hohmann, Afshan B. Hameed , et al. · 2021

This retrospective cohort study found that women with COVID-19 giving birth had higher rates of mortality, intubation, ICU admission, and preterm birth than women without COVID-19.

Management of Women With Acquired Cardiovascular Disease From Pre-Conception Through Pregnancy and Postpartum Open

Ki Park, C. Noel Bairey Merz, Natalie A. Bello, Melinda B. Davis, Claire S. Duvernoy , et al. · 2021

78 Preeclampsia Diminishes Pregnancy-augmented Myometrial H2S Biosynthesis and Myometrial Artery Cystathionine ß-Synthase Expression in Women Open

Joshua Makhoul, Thomas J. Lechuga, Robert C. Day, Qian-Rong Qi, Carol Major , et al. · 2021

California Cardiovascular Screening Tool: Findings from Initial Implementation Open

Elizabeth Blumenthal, Adam Crosland, Dana Senderoff, Kathryn Santurino, Nisha Garg , et al. · 2020

Objective American College of Obstetricians and Gynecologists (ACOG) recently published the California (CA) cardiovascular disease (CVD) screening algorithm for pregnant and postpartum women. We aim to prospectively determine screen-positi…

Society for Maternal-Fetal Medicine Special Statement: Updated checklist for antepartum care of pregestational diabetes mellitus Open

Afshan B. Hameed, C. Andrew Combs · 2020

Preemptive cardiac resynchronization therapy to prevent cardiac arrest in peripartum cardiomyopathy: a case report Open

Taizoon Q Dhoon, Simon Kim, Yashar Eshraghi, Rachel Perry, Afshan B. Hameed , et al. · 2020

Select patients with peripartum cardiomyopathy are candidates for implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy (CRT) due to the increased risk for life threatening arrhythmias and sudden death. We prese…

Society for Maternal-Fetal Medicine Special Statement: Checklist for postpartum discharge of women with hypertensive disorders Open

Kelly S. Gibson, Afshan B. Hameed · 2020

Afshan B. Hameed YOU? Author Swipe