Explanipedia

622 Fibroblast function in vitro modulated by the melanocortin tripeptide derivatives KdPT and WOL074-029 Open

Agatha Stegemann, Michael Soeberdt, Christoph Abels, Kerstin Steinbrink, Markus Böhm · 2022

617 Endothelial to mesenchymal transition - a novel field of action of the alpha7 nicotinic acetylcholine receptor? Open

Agatha Stegemann, Z. Pethö, V. Raker, A. Schwab, K. Steinbrink , et al. · 2022

Supplementary Material for: Expression of the α7 Nicotinic Acetylcholine Receptor is Critically Required for the Antifibrotic Effect of PHA-543613 on Skin Fibrosis Open

Agatha Stegemann, Verena Raker, A delRey, Kerstin Steinbrink, Markus Böhm · 2021

Medicine

Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma Open

Carsten Weishaupt, Arianna Mastrofrancesco, Dieter Metze, Björn Kemper, Agatha Stegemann , et al. · 2020

Although recent therapeutic developments raise hope, melanoma remains a devastating disease with a need for new treatment targets. In other tumours prohormone convertases have been shown to be pro-tumourigenic as they are involved in proce…

628 Activation of the alpha7 nicotinic acetylcholine receptor improves skin fibrosis Open

Agatha Stegemann, Markus Böhm · 2019

The α7 nicotinic acetylcholine receptor agonist tropisetron counteracts ultraviolet A‐mediated oxidative stress in human dermal fibroblasts Open

Agatha Stegemann, Markus Böhm · 2016

Ultraviolet A (UVA) exposure is a well-known contributor to cutaneous photoageing. Accordingly, reactive oxygen species (ROS) including H2O2 are released by dermal fibroblasts upon UVA exposure leading to elevated expression of matrix meta…

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