Agathe Heyraud
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View article: Human bone marrow derived stem cell differentiation on 3D printed bioactive glass scaffolds
Human bone marrow derived stem cell differentiation on 3D printed bioactive glass scaffolds Open
Bioactive glass particles have previously been found to stimulate new bone growth in vivo and have a long clinical track record. The effect of bioactive glasses on human bone marrow derived stromal cells (hBMSCs) has not been clearly ascer…
View article: Ionic release from bioactive SiO2-CaOCME/poly(tetrahydrofuran)/poly(caprolactone) hybrids drives human-bone marrow stromal cell osteogenic differentiation
Ionic release from bioactive SiO2-CaOCME/poly(tetrahydrofuran)/poly(caprolactone) hybrids drives human-bone marrow stromal cell osteogenic differentiation Open
This study demonstrates that dissolution products of inorganic/organic SiO2-CaOCME/PTHF/PCL-diCOOH hybrid (70S30CCME-CL) drive human bone marrow stromal cells (h-BMSCs) down an osteogenic pathway with the production of mineralised matrix. …
View article: Ovine Mesenchymal Stem Cell Chondrogenesis on a Novel 3D-Printed Hybrid Scaffold In Vitro
Ovine Mesenchymal Stem Cell Chondrogenesis on a Novel 3D-Printed Hybrid Scaffold In Vitro Open
This study evaluated the use of silica/poly(tetrahydrofuran)/poly(ε-caprolactone) (SiO2/PTHF/PCL-diCOOH) 3D-printed scaffolds, with channel sizes of either 200 (SC-200) or 500 (SC-500) µm, as biomaterials to support the chondrogenesis of s…
View article: Calcium sources can increase mechanical properties of 3D printed bioactive hybrid bone scaffolds
Calcium sources can increase mechanical properties of 3D printed bioactive hybrid bone scaffolds Open
A bioactive hybrid material for bone implants, synthesised via the sol–gel route and incorporating calcium, and 3D-printed into an interconnected porous scaffold.
View article: 3D printed hybrid scaffolds for bone regeneration using calcium methoxyethoxide as a calcium source
3D printed hybrid scaffolds for bone regeneration using calcium methoxyethoxide as a calcium source Open
Introduction: Hybrids consist of inorganic and organic co-networks that are indistinguishable above the nanoscale, which can lead to unprecedented combinations of properties, such as high toughness and controlled degradation. Methods: We p…
View article: Exploratory Full-Field Mechanical Analysis across the Osteochondral Tissue—Biomaterial Interface in an Ovine Model
Exploratory Full-Field Mechanical Analysis across the Osteochondral Tissue—Biomaterial Interface in an Ovine Model Open
Osteochondral injuries are increasingly prevalent, yet success in articular cartilage regeneration remains elusive, necessitating the development of new surgical interventions and novel medical devices. As part of device development, anima…
View article: Quantifying 3D Strain in Scaffold Implants for Regenerative Medicine
Quantifying 3D Strain in Scaffold Implants for Regenerative Medicine Open
Regenerative medicine solutions require thoughtful design to elicit the intended biological response. This includes the biomechanical stimulus to generate an appropriate strain in the scaffold and surrounding tissue to drive cell lineage t…