Agnes Langat
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View article: Advancing functional and systemic integration of HIV prevention into public health systems
Advancing functional and systemic integration of HIV prevention into public health systems Open
The global HIV response has delivered substantial progress, largely through vertical programmes that created parallel systems of financing, governance, and service delivery. Sustaining these gains requires embedding HIV prevention more ful…
View article: Factors associated with cervical cancer screening among women attending maternal child health clinics in Kenya
Factors associated with cervical cancer screening among women attending maternal child health clinics in Kenya Open
View article: Factors associated with cervical cancer screening among women attending maternal child health clinics in Kenya.
Factors associated with cervical cancer screening among women attending maternal child health clinics in Kenya. Open
Background : Cervical cancer is the second leading malignancy among women in sub-Saharan Africa. Early detection through screening and treatment of pre-cancerous cervical lesions is paramount in preventing cervical cancer. We sought to exa…
View article: Intact HIV DNA decays in children with and without complete viral load suppression
Intact HIV DNA decays in children with and without complete viral load suppression Open
To inform cure in children living with HIV (CWH), we elucidated the dynamics and mechanisms underlying HIV persistence during antiretroviral therapy (ART). In 120 Kenyan CWH who initiated ART between 1-12 months of age, 55 had durable vira…
View article: PP4.17 – 00063 Distinct immune profiles in children living with HIV based on timing and duration of suppressive antiretroviral treatment Madeline
PP4.17 – 00063 Distinct immune profiles in children living with HIV based on timing and duration of suppressive antiretroviral treatment Madeline Open
View article: PP2.7 – 00034 The Cross-Subtype Intact Proviral DNA Assay Detects >97% of Proviral Sequences from Diverse HIV Clades
PP2.7 – 00034 The Cross-Subtype Intact Proviral DNA Assay Detects >97% of Proviral Sequences from Diverse HIV Clades Open
View article: ST2.2 – 00065 Models and correlates of intact and defective HIV DNA decay in Kenyan children over 8 years of ART
ST2.2 – 00065 Models and correlates of intact and defective HIV DNA decay in Kenyan children over 8 years of ART Open
View article: Distinct immune profiles in children living with HIV based on timing and duration of suppressive antiretroviral treatment
Distinct immune profiles in children living with HIV based on timing and duration of suppressive antiretroviral treatment Open
Timely initiation of antiretroviral therapy (ART) remains a major challenge in the effort to treat children living with HIV (“CLH”) and little is known regarding the dynamics of immune normalization following ART in CLH with varying times …
View article: Factors associated with exclusive breastfeeding by maternal HIV status: a population-based survey in Kenya
Factors associated with exclusive breastfeeding by maternal HIV status: a population-based survey in Kenya Open
Background Exclusive breastfeeding (EBF) in the first six months remains low globally, despite known benefits of lower morbidity and mortality among breastfed infants. It is important to understand factors associated with breastfeeding to …
View article: Predictors of intact HIV DNA levels among children in Kenya
Predictors of intact HIV DNA levels among children in Kenya Open
Objective: We determined predictors of both intact (estimate of replication-competent) and total (intact and defective) HIV DNA in the reservoir among children with HIV. Design: HIV DNA in the reservoir was quantified longitudinally in chi…
View article: The development of task sharing policy and guidelines in Kenya
The development of task sharing policy and guidelines in Kenya Open
View article: Group antenatal care for improving retention of adolescent and young pregnant women living with HIV in Kenya
Group antenatal care for improving retention of adolescent and young pregnant women living with HIV in Kenya Open
View article: The Development of Task Sharing Policy and Guidelines in Kenya
The Development of Task Sharing Policy and Guidelines in Kenya Open
Background: The global critical shortage of health workers prevents expansion of healthcare services and universal health coverage. Like most countries in sub-Saharan Africa, Kenya’s healthcare workforce density of 13.8 health workers per …
View article: Associations of Sociodemographic and Clinical Factors with Late Presentation for Early Infant HIV Diagnosis (EID) Services in Kenya
Associations of Sociodemographic and Clinical Factors with Late Presentation for Early Infant HIV Diagnosis (EID) Services in Kenya Open
Background: Understanding the missed opportunities in early infant HIV testing within the PMTCT program is essential to address any gaps. The study set out to describe the clinical and sociodemographic characteristics of the infants presen…
View article: Higher prevalence of stunting and poor growth outcomes in HIV-exposed uninfected than HIV-unexposed infants in Kenya
Higher prevalence of stunting and poor growth outcomes in HIV-exposed uninfected than HIV-unexposed infants in Kenya Open
Background: With the growing population of HIV-exposed uninfected (HEU) children globally, it is important to determine population-level growth differences between HEU and HIV-unexposed uninfected (HUU) children. Methods: We analyzed data …
View article: Improving retention in antenatal and postnatal care: a systematic review of evidence to inform strategies for adolescents and young women living with HIV
Improving retention in antenatal and postnatal care: a systematic review of evidence to inform strategies for adolescents and young women living with HIV Open
Introduction Young pregnant and postpartum women living with HIV (WLHIV) are at high risk of poor outcomes in prevention of mother‐to‐child transmission services. The aim of this systematic review was to collate evidence on strategies to i…
View article: Contraceptive counseling experiences among women attending HIV care and treatment centers: A national survey in Kenya
Contraceptive counseling experiences among women attending HIV care and treatment centers: A national survey in Kenya Open
OBJECTIVES: To characterize contraceptive counseling experiences among women living with HIV (WLWH) receiving HIV care in Kenya. STUDY DESIGN: Sexually active, WLWH aged 15–49 years were purposively sampled from 109 high-volume HIV Care an…
View article: Correlates of cervical cancer screening among women living with HIV in Kenya: A cross‐sectional study
Correlates of cervical cancer screening among women living with HIV in Kenya: A cross‐sectional study Open
Objective Cervical cancer is the leading cause of cancer‐related death among Kenyan women. It is important to identify how demographics and knowledge of cervical cancer are associated with screening to determine best practices for targeted…
View article: Factors associated with the timely uptake of initial HIV virologic test among HIV-exposed infants attending clinics within a faith-based HIV program in Kenya; a cross-sectional study
Factors associated with the timely uptake of initial HIV virologic test among HIV-exposed infants attending clinics within a faith-based HIV program in Kenya; a cross-sectional study Open
Background Early infant diagnosis (EID) of HIV, followed by effective care including antiretroviral therapy (ART), reduces infant mortality by 76% and HIV progression by 75%. In 2015, 50% of 1.2 million HIV-exposed infants (HEI) in 21 prio…
View article: Group Antenatal Care for Improving Retention of Adolescent and Young Pregnant Women Living With HIV in Kenya
Group Antenatal Care for Improving Retention of Adolescent and Young Pregnant Women Living With HIV in Kenya Open
View article: Association Between Cytomegalovirus and Epstein-Barr Virus Viremia And Human Immunodeficiency Virus DNA Levels in the Reservoir of Kenyan Infants Receiving Antiretroviral Therapy
Association Between Cytomegalovirus and Epstein-Barr Virus Viremia And Human Immunodeficiency Virus DNA Levels in the Reservoir of Kenyan Infants Receiving Antiretroviral Therapy Open
Identifying determinants of human immunodeficiency virus (HIV) reservoir levels may inform novel viral eradication strategies. Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) coinfections were assessed as predictors of HIV proviral DNA …
View article: Higher contraceptive uptake in HIV treatment centers offering integrated family planning services: A national survey in Kenya
Higher contraceptive uptake in HIV treatment centers offering integrated family planning services: A national survey in Kenya Open
View article: Male partner antenatal clinic attendance is associated with increased uptake of maternal health services and infant BCG immunization: a national survey in Kenya
Male partner antenatal clinic attendance is associated with increased uptake of maternal health services and infant BCG immunization: a national survey in Kenya Open
Involving male partners in MCH activities amplifies benefits of MCH services by engaging partner support for maternal uptake of services.
View article: High Plasma Soluble CD163 During Infancy Is a Marker for Neurocognitive Outcomes in Early-Treated HIV-Infected Children
High Plasma Soluble CD163 During Infancy Is a Marker for Neurocognitive Outcomes in Early-Treated HIV-Infected Children Open
Background: Monocyte activation may contribute to neuronal injury in aviremic HIV-infected adults; data are lacking in children. We examined the relation between monocyte activation markers and early and long-term neurodevelopmental outcom…
View article: Preexposure Prophylaxis for Human Immunodeficiency Virus (HIV) Prevention Among HIV–uninfected Pregnant Women: Estimated Coverage Using Risk-based Versus Regional Prevalence Approaches
Preexposure Prophylaxis for Human Immunodeficiency Virus (HIV) Prevention Among HIV–uninfected Pregnant Women: Estimated Coverage Using Risk-based Versus Regional Prevalence Approaches Open
Antenatal register data from 62 clinics in 5 regions of Kenya were used to estimate women with human immunodeficiency virus (HIV) risk (partner HIV status, syphilis). With individual risk-guided preexposure prophylaxis (PrEP) offer in all …
View article: Beyond Early Infant Diagnosis: Changing the Approach to HIV-Exposed Infants
Beyond Early Infant Diagnosis: Changing the Approach to HIV-Exposed Infants Open
Despite dramatic global progress with implementing prevention of mother-to-child HIV transmission (PMTCT) programs, there were 160,000 new pediatric HIV infections in 2016. More than 50% of infant HIV infections now occur in the postpartum…
View article: Prevalence and correlates of non-disclosure of maternal HIV status to male partners: a national survey in Kenya
Prevalence and correlates of non-disclosure of maternal HIV status to male partners: a national survey in Kenya Open
View article: Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants
Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants Open
We compared change in HIV reservoir DNA following continued antiretroviral therapy (ART) vs short treatment interruption (TI) in early ART-treated Kenyan infants. While HIV DNA in the reservoir decayed with continued ART, HIV DNA levels we…
View article: 4th National Anti-tuberculosis Drug Resistance Survey in Kenya
4th National Anti-tuberculosis Drug Resistance Survey in Kenya Open
Introduction: Recently rapid development of drug resistant TB, particularly MDR TB (Multi Drug Resistant TB) and XDRTB (Extensively Drug-Resistant TB) possess a major threat to control of tuberculosis globally.Information on the extent of …
View article: Non-disclosure to male partners and incomplete PMTCT regimens associated with higher risk of mother-to-child HIV transmission: a national survey in Kenya
Non-disclosure to male partners and incomplete PMTCT regimens associated with higher risk of mother-to-child HIV transmission: a national survey in Kenya Open
Health worker experience and community support may be higher in high HIV prevalence regions than low prevalence regions, leading to improved prevention of mother-to-child HIV transmission (PMTCT) programs. We evaluated 6-week and 9-month i…