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View article: Insights into the evolution and regulation of hybrid internal-terminal exons from tropomyosin exon 9A in Xenopus laevis
Insights into the evolution and regulation of hybrid internal-terminal exons from tropomyosin exon 9A in Xenopus laevis Open
Hybrid internal-terminal exons function as either internal or terminal exons. Their evolutionary origins remain unclear. Here, we investigate the phylogenetic origin and regulation of a hybrid exon, 9A9', in the TPM1 gene encoding tropomyo…
View article: Proteomic study identifies Aurora-A–mediated regulation of alternative splicing through multiple splicing factors
Proteomic study identifies Aurora-A–mediated regulation of alternative splicing through multiple splicing factors Open
The cell cycle regulator Aurora-A kinase presents an attractive target for cancer therapies, though its inhibition is also associated with toxic side effects. To gain a more nuanced understanding of Aurora-A function, we applied shotgun pr…
View article: Supplementary Table 3 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Table 3 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Differential gene expression
View article: Figure S1 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Figure S1 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
TP63 gene structure and annotation
View article: Supplementary Figure 7 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 7 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
RIP controls and EMSA
View article: Supplementary Figure 8 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 8 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
endogenous TP63 regulation is unaffected in HaCaT cell lines expressing minigenes
View article: Supplementary Table 4 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Table 4 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
GO term enrichment analysis
View article: Supplementary Table 1 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Table 1 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Reagents table
View article: Data from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Data from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
The TP63 gene encodes the p63 transcription factor. It is frequently amplified or overexpressed in squamous cell carcinomas. Owing to alternative splicing, p63 has multiple isoforms called α, β, γ, and δ. The regulatory functions of p63 ar…
View article: Supplementary Figure 5 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 5 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
PTBP1 controls TP63 splicing in HNSCC, additional RTqPCR
View article: Supplementary Figure 7 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 7 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
RIP controls and EMSA
View article: Supplementary Figure 6 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 6 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Conservation of TP63 splicing regulation by PTBP1 in vertebrates
View article: Supplementary Table 2 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Table 2 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Results of the dunnet's tests presented in the figures
View article: Supplementary Table 3 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Table 3 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Differential gene expression
View article: Supplementary Figure 3 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 3 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Alternative junction usage for TP63 in GTEX data
View article: Supplementary Figure 3 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 3 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Alternative junction usage for TP63 in GTEX data
View article: Supplementary Table 4 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Table 4 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
GO term enrichment analysis
View article: Supplementary Figure 6 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 6 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Conservation of TP63 splicing regulation by PTBP1 in vertebrates
View article: Supplementary Figure 2 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 2 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
TP63 isoforms splicing in patients segregated by HPV status
View article: Figure S1 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Figure S1 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
TP63 gene structure and annotation
View article: Supplementary Figure 5 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 5 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
PTBP1 controls TP63 splicing in HNSCC, additional RTqPCR
View article: Supplementary Table 2 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Table 2 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Results of the dunnet's tests presented in the figures
View article: Supplementary Figure 4 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 4 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Terminal TP63 gamma exon in tissues
View article: Supplementary Figure 4 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 4 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Terminal TP63 gamma exon in tissues
View article: Supplementary Table 1 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Table 1 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
Reagents table
View article: Data from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Data from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
The TP63 gene encodes the p63 transcription factor. It is frequently amplified or overexpressed in squamous cell carcinomas. Owing to alternative splicing, p63 has multiple isoforms called α, β, γ, and δ. The regulatory functions of p63 ar…
View article: Supplementary Figure 8 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 8 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
endogenous TP63 regulation is unaffected in HaCaT cell lines expressing minigenes
View article: Supplementary Figure 2 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
Supplementary Figure 2 from The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
TP63 isoforms splicing in patients segregated by HPV status
View article: The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma
The Splicing Factor PTBP1 Represses <i>TP63 γ</i> Isoform Production in Squamous Cell Carcinoma Open
The TP63 gene encodes the p63 transcription factor. It is frequently amplified or overexpressed in squamous cell carcinomas. Owing to alternative splicing, p63 has multiple isoforms called α, β, γ, and δ. The regulatory functions of p63 ar…