Agnieszka Lewandowska
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View article: CCDC 2202274: Experimental Crystal Structure Determination
CCDC 2202274: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2202275: Experimental Crystal Structure Determination
CCDC 2202275: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Temozolomide: a cytostatic drug that is still important today
Temozolomide: a cytostatic drug that is still important today Open
TMZ has an advantage over other traditional alkylating agents (carmustine, lomustine, procarbazine), which are highly toxic and have poor patient survival. TMZ circumvents these problems because cytochrome P450 enzymes and the kidneys are …
View article: CCDC 1984555: Experimental Crystal Structure Determination
CCDC 1984555: Experimental Crystal Structure Determination Open
View article: CCDC 1984554: Experimental Crystal Structure Determination
CCDC 1984554: Experimental Crystal Structure Determination Open
View article: Describing Antifungal Drug-Sterol Interactions Inside the Membrane: The Role of Dynamics
Describing Antifungal Drug-Sterol Interactions Inside the Membrane: The Role of Dynamics Open
View article: Sterol Interactions with Amphotericin Sponge: Dynamics Drive Affinity
Sterol Interactions with Amphotericin Sponge: Dynamics Drive Affinity Open
View article: A comparison of biological activity of commercially available purified native botulinum neurotoxin serotypes A1 to F1 in vitro, ex vivo, and in vivo
A comparison of biological activity of commercially available purified native botulinum neurotoxin serotypes A1 to F1 in vitro, ex vivo, and in vivo Open
Botulinum neurotoxin (Bo NT ) is a major therapeutic agent. Of seven native Bo NT serotypes (A to G), only A and B are currently used in the clinic. Here we compared the potency of commercially available purified native serotypes A1 to F1 …
View article: Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration
Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration Open
It has long been postulated, although never directly demonstrated, that mitochondria are strategically positioned in the cytoplasm to meet local requirements for energy production. Here we show that positioning of mitochondria in mouse emb…
View article: A Novel Method for Force-Field Calibration Based on Maximum-Likelihood Approach and Thermal Unfolding Data
A Novel Method for Force-Field Calibration Based on Maximum-Likelihood Approach and Thermal Unfolding Data Open
View article: Miro1 is Dispensable for Calcium-Mediated Inhibition of Mitochondrial Movement
Miro1 is Dispensable for Calcium-Mediated Inhibition of Mitochondrial Movement Open