Agostino Riva
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View article: Correction: Health profiles of foreign-born elderly women with HIV in Italy
Correction: Health profiles of foreign-born elderly women with HIV in Italy Open
View article: Early results from implementation of HIV pre-exposure prophylaxis (PrEP) with long-acting injectable cabotegravir for people with barriers to oral strategies, Italy, December 2024 to August 2025
Early results from implementation of HIV pre-exposure prophylaxis (PrEP) with long-acting injectable cabotegravir for people with barriers to oral strategies, Italy, December 2024 to August 2025 Open
Between December 2024 and August 2025, two Italian HIV/STI clinics offered long-acting injectable cabotegravir (CAB-LA) for HIV prevention in 265 individuals, representing the first European real-world implementation. Participants were pri…
View article: Health profiles of foreign-born elderly women with HIV in Italy
Health profiles of foreign-born elderly women with HIV in Italy Open
Background Ageing trajectories for foreign-born individuals and women living with HIV remain poorly defined globally. This study aimed to characterize foreign-born women living with HIV aged ≥65 years (FWLH) and compare them to age-matched…
View article: High Effectiveness of Ceftriaxone Monotherapy and Limited Value of Routine Test-of-Cure for Gonorrhea in a Low-Resistance Setting
High Effectiveness of Ceftriaxone Monotherapy and Limited Value of Routine Test-of-Cure for Gonorrhea in a Low-Resistance Setting Open
View article: Unilateral uveitis following adjuvanted Varicella-Zoster subunit vaccine in a patient with previously resolved Varicella Zoster acute retinal necrosis
Unilateral uveitis following adjuvanted Varicella-Zoster subunit vaccine in a patient with previously resolved Varicella Zoster acute retinal necrosis Open
PURPOSE: To report a case of intraocular inflammation following adjuvanted recombinant Varicella-Zoster subunit vaccine (RZV) in a patient with previously resolved VZV-related acute retinal necrosis (ARN). METHODS: Single case report. Mult…
View article: NAT2 Acetylation Status Predicts Hepatotoxicity During Antituberculosis Therapy: Cumulative Risk Analysis of a Multiethnic Cohort
NAT2 Acetylation Status Predicts Hepatotoxicity During Antituberculosis Therapy: Cumulative Risk Analysis of a Multiethnic Cohort Open
Antituberculosis drug-induced hepatotoxicity (ATDH) is a common adverse drug reaction often requiring treatment interruption, complicating tuberculosis management. The slow acetylator phenotype, characterized by reduced N-acetyltransferase…
View article: SARS-CoV-2 infectivity can be modulated through bacterial grooming of the glycocalyx
SARS-CoV-2 infectivity can be modulated through bacterial grooming of the glycocalyx Open
The gastrointestinal (GI) tract is a site of replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and GI symptoms are often reported by patients. SARS-CoV-2 cell entry depends upon heparan sulfate (HS) proteoglycans,…
View article: Genomic Epidemiology of the Main SARS‐CoV‐2 Variants Circulating in Italy During the Omicron Era
Genomic Epidemiology of the Main SARS‐CoV‐2 Variants Circulating in Italy During the Omicron Era Open
Since early 2022 the Omicron variant has rapidly spread worldwide, becoming the dominant variant to date. The study aimed to investigate the clinical and epidemiological characteristics of COVID‐19 patients and reconstruct the genomic epid…
View article: Modulation of CCR5 expression and R5 HIV-1 infection in primary macrophages exposed to sera from HESN, LTNP, and chronically HIV-1 infected people with or without natural antibodies to CCR5
Modulation of CCR5 expression and R5 HIV-1 infection in primary macrophages exposed to sera from HESN, LTNP, and chronically HIV-1 infected people with or without natural antibodies to CCR5 Open
View article: Patterns of C1-Inhibitor Plasma Levels and Kinin–Kallikrein System Activation in Relation to COVID-19 Severity
Patterns of C1-Inhibitor Plasma Levels and Kinin–Kallikrein System Activation in Relation to COVID-19 Severity Open
Background: Although more than four years have passed since the pandemic began, SARS-CoV-2 continues to be of concern. Therefore, research into the underlying mechanisms that contribute to the development of the disease, especially in more…
View article: Operationalisation of post‐COVID condition case definition in a comprehensive research protocol
Operationalisation of post‐COVID condition case definition in a comprehensive research protocol Open
Background and purpose Post‐COVID‐19 condition (PCC) is a prevalent and high‐burden sequela of SARS‐CoV‐2 infection. Because of the complexity of its manifestations, PCC case definition currently lacks standardisation and reproducibility. …
View article: Impact of early antiviral therapy on SARS-CoV-2 clearance time in high-risk COVID-19 subjects: A propensity score matching study
Impact of early antiviral therapy on SARS-CoV-2 clearance time in high-risk COVID-19 subjects: A propensity score matching study Open
Early treatments play a crucial role in reducing SARS-CoV-2 viral shedding and preventing disease progression among high-risk individuals. Shorter viral shedding duration also contributes to improved healthcare resource utilization and inf…
View article: Hospital-Based Influenza and Pneumococcal Vaccination for Cancer Patients on Active Treatment and Their Family Members during the COVID-19 Pandemic in Italy: A Single-Center Experience
Hospital-Based Influenza and Pneumococcal Vaccination for Cancer Patients on Active Treatment and Their Family Members during the COVID-19 Pandemic in Italy: A Single-Center Experience Open
In patients with cancer, tumor- and treatment-induced immunosuppression are responsible for a four-fold increase in morbidity and mortality caused by influenza and invasive Streptococcus pneumoniae infections compared to the general popula…
View article: Early administration of nirmatrelvir/ritonavir leads to faster negative SARS-CoV-2 nasal swabs than monoclonal antibodies in COVID 19 patients at high-risk for severe disease
Early administration of nirmatrelvir/ritonavir leads to faster negative SARS-CoV-2 nasal swabs than monoclonal antibodies in COVID 19 patients at high-risk for severe disease Open
View article: Long-term effects of SARS-CoV-2 infection in hospitalized children: findings from an Italian single-center study
Long-term effects of SARS-CoV-2 infection in hospitalized children: findings from an Italian single-center study Open
View article: A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death
A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death Open
View article: Antibody response to three‐dose <scp>anti‐SARS‐CoV</scp>‐2 <scp>mRNA</scp>‐vaccination in treated solid cancer patients
Antibody response to three‐dose <span>anti‐SARS‐CoV</span>‐2 <span>mRNA</span>‐vaccination in treated solid cancer patients Open
Solid cancer patients are at higher risk of SARS‐CoV‐2 infection and severe complications. Moreover, vaccine‐induced antibody response is impaired in patients on anticancer treatment. In this retrospective, observational, hypothesis‐genera…
View article: Genomic epidemiology of the main SARS‐CoV‐2 variants in Italy between summer 2020 and winter 2021
Genomic epidemiology of the main SARS‐CoV‐2 variants in Italy between summer 2020 and winter 2021 Open
Since the beginning of the pandemic, SARS‐CoV‐2 has shown a great genomic variability, resulting in the continuous emergence of new variants that has made their global monitoring and study a priority. This work aimed to study the genomic h…
View article: What do we mean by <scp>long COVID</scp>? A scoping review of the cognitive sequelae of <scp>SARS‐CoV</scp>‐2 infection
What do we mean by <span>long COVID</span>? A scoping review of the cognitive sequelae of <span>SARS‐CoV</span>‐2 infection Open
Background and purpose Many COVID‐19 patients report persistent symptoms, including cognitive disturbances. We performed a scoping review on this topic, focusing primarily on cognitive manifestations. Methods Abstracts and full texts of st…
View article: Genomic epidemiology of the main SARS-CoV-2 variants circulating in Italy in 2020 and 2022 period
Genomic epidemiology of the main SARS-CoV-2 variants circulating in Italy in 2020 and 2022 period Open
Since the beginning of the pandemic, SARS-CoV-2 has shown a great genomic variability, resulting in the continuous emergence of new variants that has made their global monitoring and study a priority. This work aimed to study the genomic h…
View article: Neutralizing antibodies response to novel SARS-CoV-2 omicron sublineages in long-term care facility residents after the fourth dose of monovalent BNT162b2 COVID-19 vaccination
Neutralizing antibodies response to novel SARS-CoV-2 omicron sublineages in long-term care facility residents after the fourth dose of monovalent BNT162b2 COVID-19 vaccination Open
View article: Ultra-rare RTEL1 gene variants associate with acute severity of COVID-19 and evolution to pulmonary fibrosis as a specific long COVID disorder
Ultra-rare RTEL1 gene variants associate with acute severity of COVID-19 and evolution to pulmonary fibrosis as a specific long COVID disorder Open
View article: Corrigendum: Definition of the immune parameters related to COVID-19 severity
Corrigendum: Definition of the immune parameters related to COVID-19 severity Open
[This corrects the article DOI: 10.3389/fimmu.2022.850846.].
View article: Clinical efficacy of the first two doses of <scp>anti‐SARS‐CoV</scp>‐2 <scp>mRNA</scp> vaccines in solid cancer patients
Clinical efficacy of the first two doses of <span>anti‐SARS‐CoV</span>‐2 <span>mRNA</span> vaccines in solid cancer patients Open
Introduction Cancer patients are frail individuals, thus the prevention of SARS‐CoV‐2 infection is essential. To date, vaccination is the most effective tool to prevent COVID‐19. In a previous study, we evaluated the immunogenicity of two …
View article: Observational Study on Antibody Response to COVID-19 Vaccines in PAtients with Gastro-Entero-PanCreatic Cancers and NeuroendocrIne NeoplAsms on Systemic TreatmEnts (VACCINATE)
Observational Study on Antibody Response to COVID-19 Vaccines in PAtients with Gastro-Entero-PanCreatic Cancers and NeuroendocrIne NeoplAsms on Systemic TreatmEnts (VACCINATE) Open
The coronavirus disease-19 (COVID-19) pandemic dramatically impacted oncological patients’ care. Since the introduction of vaccines and the demonstration of their benefit on frail patients, COVID-19 vaccinations were indicated to also be b…
View article: Observational study on antibody response to COVID-19 Vaccines in pAtients with gastro-entero-panCreatic Cancers and neuroendocrIne NeoplAsms on systemic TreatmEnts (VACCINATE).
Observational study on antibody response to COVID-19 Vaccines in pAtients with gastro-entero-panCreatic Cancers and neuroendocrIne NeoplAsms on systemic TreatmEnts (VACCINATE). Open
The Coronavirus disease-19 (COVID-19) pandemic dramatically impacted on oncologic patients' care. Since the introduction of vaccines and the demonstration of their benefit on frail patients, COVID-19 vaccinations were indicated also for on…
View article: Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape
Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape Open
View article: Epidemiological and Clinical Features of SARS-CoV-2 Variants Circulating between April–December 2021 in Italy
Epidemiological and Clinical Features of SARS-CoV-2 Variants Circulating between April–December 2021 in Italy Open
SARS-CoV-2 is constantly evolving, leading to new variants. We analysed data from 4400 SARS-CoV-2-positive samples in order to pursue epidemiological variant surveillance and to evaluate their impact on public health in Italy in the period…
View article: An explainable model of host genetic interactions linked to COVID-19 severity
An explainable model of host genetic interactions linked to COVID-19 severity Open
View article: Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape
Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape Open
SUMMARY Memory B cells (MBCs) generate rapid antibody responses upon secondary encounter with a pathogen. Here, we investigated the kinetics, avidity and cross-reactivity of serum antibodies and MBCs in 155 SARS-CoV-2 infected and vaccinat…