Explanipedia

In silico assessment of antioxidant activity and toxicity profiling of bioactive molecules from Murraya koenigii Open

Krishn Kumar Agrawal, Ashita Yadav, Shivendra Kumar, Sunam Saha, Kuldeep Singh , et al. · 2024

The antioxidant activity of curry leaves is of interest because oxidative stress is implicated in a variety of diseases, including cancer, heart disease, and neurodegenerative disorders. By scavenging free radicals and inhibiting lipid per…

A systematic review on anticancer potential of traditional Chinese medicine (Yang Zheng XiaoJi) Open

Krishn Kumar Agrawal, Yogesh Murti · 2024

Background: The term ''cancer'' refers to illnesses in which cells can proliferate uncontrollably, infiltrate, and spread to various body organs. Since it has been used for thousands of years, traditional Chinese medicine (TCM) is now comm…

Review of: "Phytochemical Contents, GC-MS Analysis and Hepatoprotective Effect of the Methanol Leaf Extract of Camelliasinensis (L.) Kuntze on Paracetamol-Induced Liver Injury in Wistar Rats" Open

Krishn Kumar Agrawal · 2024

2310P Oxygen nano-bubbles attenuate hypoxia-induced tumour malignancy in tumour xenograft models Open

Kumari Bhavya, Krishn Kumar Agrawal, Deepa Negi, Karishma Niveria, Anita Verma , et al. · 2023

Moderate Stress Level among Patients Undergoing Hemodialysis in a Tertiary Care Centre Open

Manoj Dhungana, Pragya Shrestha, Sundar Pandey, Sreya Paudyal, Krishn Kumar Agrawal · 2023

Introduction: Stress is the response of body to any change. The end stage of renal disease and the process of haemodialysis treatment are long-term stressors that alter patients’ well-being and everyday lifestyle. The aim of this study was…

Penicillin reduces latent rheumatic-heart-disease progression Open

Thomas Pilgrim, Krishn Kumar Agrawal · 2022

<i>WFS1</i> Gene–associated Diabetes Phenotypes and Identification of a Founder Mutation in Southern India Open

Aaron Chapla, Jabasteen Johnson, Sophy Korula, Nisha Mohan, Anish Ahmed , et al. · 2022

Context Wolfram syndrome (WFS) is a rare autosomal recessive disorder characterized by juvenile-onset diabetes, diabetes insipidus, optic atrophy, deafness, and progressive neurodegeneration. However, due to the progressive nature of the d…

Prevalence of latent structural heart disease in Nepali schoolchildren Open

Nikesh Raj Shrestha, Surendra Uranw, Prahlad Karki, Santosh Bastola, Rajan Kumar Mahato , et al. · 2021

Background: The present study aimed to quantify the burden of structural heart disease in Nepali children. Methods: We performed a school-based cross-sectional echocardiographic screening study with cluster random sampling among children 5…

Hepatoprotective Molecules and Extracts Profile from Calotropis procera R. Br. Open

Krishn Kumar Agrawal, Yogesh Murti · 2021

Plants have a great value as the source of medicine. They are most utilized in ayurveda medicine of system for the treatment of various ailments without and/or less adverse effect.Calotropisprocera is shrubby medicinal plant that evenly gr…

Mid-term outcome of children with latent rheumatic heart disease in eastern Nepal Open

Nikesh Raj Shrestha, Dorothea Bruelisauer, Surendra Uranw, Rajan Kumar Mahato, Kunjang Sherpa , et al. · 2021

Introduction Systematic echocardiographic screening of children in regions with an endemic pattern of rheumatic heart disease allows for the early detection of valvular lesions suggestive of subclinical rheumatic heart disease. The natural…

Prevalance of Elevated D-dimer Levels in Confirmed COVID-19 Cases in Intensive Care Unit of a Tertiary Care Centre of Western Nepal Open

Prabin Khatri, Krishn Kumar Agrawal, Dipesh Sharma, Pradip Chhetri, Aryan Neupane , et al. · 2021

Introduction: D-dimer is currently the best available marker for COVID-19 associated hemostatic abnormalities. This study aims to find out the prevelance of elevated D-dimer levels in confirmed COVID-19 cases in intensive care unit of a te…

Effectiveness of Systematic Echocardiographic Screening for Rheumatic Heart Disease in Nepalese Schoolchildren Open

Prahlad Karki, Surendra Uranw, Santosh Bastola, Rajan Kumar Mahato, Nikesh Raj Shrestha , et al. · 2021

ClinicalTrials.gov Identifier: NCT01550068.

Roles of Therapeutic Bioactive Compounds in Hepatocellular Carcinoma Open

Divya Jain, Yogesh Murti, Wasi Ullah Khan, Rajib Hossain, Mohammad Nabil Hossain , et al. · 2021

Hepatocellular carcinoma (HCC) is due to poor prognosis and lack of availability of effective treatment. Novel therapeutic strategies will be the fine tuning of intracellular ROS signaling to effectively deprive cells of ROS‐induced tumor‐…

THE The effect of plant defence elicitor on Costus igneus for the enhanced phytochemical productivity Open

Rajiv K. Saxena, Kartik Chaudhary, Krishn Kumar Agrawal, Thomson Santosh Alex, Prem Chand Gupta , et al. · 2019

Medicinal Plants have proven potential of treating and preventing various disorders and illness from the ancient time. Many Phytopharmaceuticals companies are emerging as a result of its popularity in both the developed as well as developi…

Prevalence of Iron Deficiency Anemia in Anemic Patients: A Hospital Based Study Open

Satyendra K. Mishra, Surendra Marasini, Badri Kumar Gupta, Krishn Kumar Agrawal, Narayan Gautam · 2018

Introduction: In developing countries like Nepal, iron deficiency anemia (IDA) is one of the major concern. The high rate incidence has been related to insufficient iron intake, accompanied by chronic intestinal blood loss due to parasitic…

Anaphylactic reactions due to pantoprazole: case report of two cases Open

P. P. Gupta, Rabin Bhandari, Deebya Raj Mishra, Krishn Kumar Agrawal, Rupak Bhandari , et al. · 2018

It is necessary for all health care providers to know that pantoprazole can cause anaphylaxis, which is a life-threatening reaction, and to be cautious while prescribing it.

Association between obesity and heart rate variability indices: an intuition toward cardiac autonomic alteration – a risk of CVD Open

Yadav RL, Yadav PK, Yadav LK, Krishn Kumar Agrawal, Sah SK , et al. · 2017

Ram Lochan Yadav,1 Prakash Kumar Yadav,1 Laxmi Kumari Yadav,2 Kopila Agrawal,3 Santosh Kumar Sah,4 Md Nazrul Islam1 1Department of Physiology, 2Department of Microbiology, Chitwan Medical College, Bharatpur, 3Department of Physiology, BP K…

Use of intrauterine balloon tamponade in successful conservative management of life threatening menorrhagia in a patient with idiopathic thrombocytopenic purpura and severe anemia Open

Rekha Agrawal, Hemant Shintre, Bindu Rani, Krishn Kumar Agrawal, Aniruddh Agrawal · 2017

A 45-year-old woman was brought into the emergency ward of a tertiary care hospital. The patient gave a history of excess bleeding and passage of clots per vaginum since the past 15 days. The patient had a history of severe headaches, body…

Prevalence of Subclinical Rheumatic Heart Disease in Eastern Nepal: A School-Based Cross-sectional Study. Open

Nikesh Raj Shrestha, Prahlad Karki, Rajan Mahto, Keshar Gurung, Naveen Kumar Pandey , et al. · 2017

Rheumatic heart disease affects 1 in 100 schoolchildren in Eastern Nepal, is primarily clinically silent, and may be more common among girls. The overall prevalence and the ratio of manifest to subclinical disease increase with advancing a…

Prevalence of Subclinical Rheumatic Heart Disease in Eastern Nepal Open

Nikesh Raj Shrestha, Prahlad Karki, Rajan Mahto, Keshar Gurung, Naveen Kumar Pandey , et al. · 2016

Importance Although rheumatic heart disease has been nearly eradicated in high-income countries, 3 in 4 children grow up in parts of the world where it is still endemic. Objectives To determine the prevalence of clinically silent and manif…

Diabetes: Emerging Pandemic Open

Krishn Kumar Agrawal, Shatdal Chaudhary · 2015

Not available. (Editorial)DOI: http://dx.doi.org/10.3126/jucms.v2i4.12072Journal of Universal College of Medical Sciences (2014) Vol. 2, No. 4 Issue 08Page : 01

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