Aziz Sheikh
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View article: A REVIEW ON URINARY TRACT DISORDERS IN CATS
A REVIEW ON URINARY TRACT DISORDERS IN CATS Open
View article: Comparative risk of end-stage renal disease, myocardial infarction and stroke in young and older onset diabetes in UK Biobank
Comparative risk of end-stage renal disease, myocardial infarction and stroke in young and older onset diabetes in UK Biobank Open
In recent years, coinciding with the increasing incidence of type 2 diabetes mellitus (T2DM) in children and adolescents, the global prevalence of diabetic kidney disease (DKD) and end-stage renal disease (ESRD) are rising year on year. In…
View article: A pilot randomised controlled trial of the Tailored Intervention for people with moderate-to-severe Chronic Obstructive Pulmonary Disease and Co-morbidities delivered by Pharmacists and Consultant respiratory Physicians (TICC-PCP)
A pilot randomised controlled trial of the Tailored Intervention for people with moderate-to-severe Chronic Obstructive Pulmonary Disease and Co-morbidities delivered by Pharmacists and Consultant respiratory Physicians (TICC-PCP) Open
View article: Systematic Review Examining the Effectiveness of Professional, Organisational and Structural Interventions in Primary Care to Reduce Medication-Related Hospitalisations and Deaths
Systematic Review Examining the Effectiveness of Professional, Organisational and Structural Interventions in Primary Care to Reduce Medication-Related Hospitalisations and Deaths Open
Organisational and structural interventions in primary care may reduce medication-related hospital admissions and may help inform clinical practice through implementation of multidisciplinary care models and system-level quality monitoring…
View article: Antenatal Corticosteroids and Infectious Diseases Throughout Childhood
Antenatal Corticosteroids and Infectious Diseases Throughout Childhood Open
Importance International guidelines recommend the use of antenatal corticosteroids (ACS) in pregnancies at risk of imminent preterm birth before 34 weeks’ gestation. However, whether ACS leads to long-term risk of infection from childhood …
View article: Mapping Use of High Dose or Long‐Term Oral Glucocorticoids and Steroid‐Sparing Strategies in Adults With Chronic Conditions: A Rapid Scoping Review of Reviews
Mapping Use of High Dose or Long‐Term Oral Glucocorticoids and Steroid‐Sparing Strategies in Adults With Chronic Conditions: A Rapid Scoping Review of Reviews Open
Purpose Oral glucocorticoids (OGCs) have a broad range of uses and are effective in treating numerous conditions. However, it is commonly acknowledged that OGCs at high doses or over long periods have a burden of toxicity. Despite the use …
View article: Children’s respiratory symptoms and London’s Ultra Low Emission Zone: the CHILL cohort study
Children’s respiratory symptoms and London’s Ultra Low Emission Zone: the CHILL cohort study Open
Background Traffic-related air pollution (TRAP) negatively affects children's respiratory health and development. Clean air zones such as London's Ultra Low Emission Zone (ULEZ) aim to reduce TRAP by discouraging high-polluting vehicles, b…
View article: From Reading to Awakening: Cultivating Critical Consciousness Through Literature, A Study of George Orwell’s Nineteen Eighty-Four.
From Reading to Awakening: Cultivating Critical Consciousness Through Literature, A Study of George Orwell’s Nineteen Eighty-Four. Open
View article: Tocilizumab versus sarilumab among adults hospitalised with COVID-19: target trial emulation across England and Scotland
Tocilizumab versus sarilumab among adults hospitalised with COVID-19: target trial emulation across England and Scotland Open
The interleukin-6 (IL-6) inhibitors tocilizumab and sarilumab have been repurposed for COVID-19 treatment. However, discrepancies still exist across global and national COVID-19 guidelines, with limited data on the comparative effectivenes…
View article: Real-world effectiveness and safety of nirsevimab, RSV maternal vaccine and RSV vaccines for older adults: a living systematic review and meta-analysis
Real-world effectiveness and safety of nirsevimab, RSV maternal vaccine and RSV vaccines for older adults: a living systematic review and meta-analysis Open
Background The long-acting monoclonal antibody nirsevimab and respiratory syncytial virus (RSV) vaccines became available for prevention of severe RSV-associated disease in 2023. While clinical trials showed good efficacy and safety, their…
View article: Randomised controlled trial to measure effectiveness and cost-effectiveness of a digital social intervention promoted by primary care clinicians to adults with asthma to improve asthma control: protocol
Randomised controlled trial to measure effectiveness and cost-effectiveness of a digital social intervention promoted by primary care clinicians to adults with asthma to improve asthma control: protocol Open
Introduction In the UK, approximately 5.4 million adults live with asthma, of whom one in five have an uncontrolled form. Uncontrolled asthma reduces quality of life and increases healthcare use. Engaging with peers through online health c…
View article: BNT162b2 COVID-19 vaccination uptake, safety, effectiveness, and waning in children and young people aged 5–11 years in Scotland
BNT162b2 COVID-19 vaccination uptake, safety, effectiveness, and waning in children and young people aged 5–11 years in Scotland Open
The BNT162b2 vaccine demonstrated a strong safety profile in this age group. Receiving both doses was linked to a reduction in the risk of symptomatic COVID-19 during the Omicron variant period, but this protection waned over the following…
View article: Vaccine effectiveness of the maternal RSVpre-F vaccine against severe disease in infants in Scotland, UK: national population-based case-control and cohort analyses
Vaccine effectiveness of the maternal RSVpre-F vaccine against severe disease in infants in Scotland, UK: national population-based case-control and cohort analyses Open
Summary Background Respiratory syncytial virus (RSV) is a leading cause of infant hospitalisation, particularly in those under six months. In response, Scotland introduced a maternal RSVpreF vaccination programme in 2024, offering the vacc…
View article: Correction: Children’s Health in London and Luton (CHILL) cohort: a 12-month natural experimental study of the effects of the Ultra Low Emission Zone on children’s travel to school
Correction: Children’s Health in London and Luton (CHILL) cohort: a 12-month natural experimental study of the effects of the Ultra Low Emission Zone on children’s travel to school Open
View article: Development path and standardization of grid-forming active support technology
Development path and standardization of grid-forming active support technology Open
In recent years, the active support control technology has been preliminarily applied and verified in various grid-forming (GFM) converters such as GFM energy storage, GFM SVG, and GFM VSC-HVDC. At present, the characteristics and stabilit…
View article: A protocol for a pilot randomised controlled trial of a Tailored Intervention for people with moderate-to-severe Chronic Obstructive Pulmonary Disease and Co-morbidities delivered by Pharmacists and Consultant respiratory Physicians (TICC-PCP) in Scotland
A protocol for a pilot randomised controlled trial of a Tailored Intervention for people with moderate-to-severe Chronic Obstructive Pulmonary Disease and Co-morbidities delivered by Pharmacists and Consultant respiratory Physicians (TICC-PCP) in Scotland Open
The trial is registered with the UK Clinical Trials Registry (ISRCTN 43508703).
View article: Sustained natural immunity following SARS-CoV-2 infection against severe COVID-19 outcomes and symptomatic reinfection: analyses of national data for Brazil and Scotland
Sustained natural immunity following SARS-CoV-2 infection against severe COVID-19 outcomes and symptomatic reinfection: analyses of national data for Brazil and Scotland Open
Objectives SARS-CoV-2 infection provides protection against reinfection and severe COVID-19 disease; however, this protective effect may diminish over time. We assessed waning of natural immunity conferred by previous infection against sev…
View article: Building capacity in the academic general practice research workforce
Building capacity in the academic general practice research workforce Open
View article: Association between income, employment status, and asthma outcomes: a systematic review and meta-analysis
Association between income, employment status, and asthma outcomes: a systematic review and meta-analysis Open
View article: An empirical assessment of differential privacy in real-world observational data: a case-control study of asthma exacerbation in UK Biobank linked with electronic health records
An empirical assessment of differential privacy in real-world observational data: a case-control study of asthma exacerbation in UK Biobank linked with electronic health records Open
Objectives Electronic health records (EHRs) provide substantial resources for observational studies, yet present significant challenges in safeguarding patient privacy while maintaining research quality. Differential privacy (DP) offers a …
View article: Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records
Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records Open
Background Clinically coded long COVID cases in electronic health records (EHRs) are incomplete, despite reports of rising cases of long COVID. Aim To determine patient characteristics associated with clinically coded long COVID. Design & …
View article: Capgras Syndrome in Schizophrenia: A Case Report of Delusional Misidentification and Its Clinical Implications
Capgras Syndrome in Schizophrenia: A Case Report of Delusional Misidentification and Its Clinical Implications Open
Aims: Capgras syndrome (CS) is a rare delusional misidentification syndrome characterized by the belief that a close relative has been replaced by an identical impostor. It is commonly associated with schizophrenia and other psychiatric di…
View article: Multicomponent intervention for controlling hypertension in the adult rural population of Pakistan: a protocol for a hybrid type III implementation-effectiveness cluster randomised controlled trial
Multicomponent intervention for controlling hypertension in the adult rural population of Pakistan: a protocol for a hybrid type III implementation-effectiveness cluster randomised controlled trial Open
Introduction Though prior trials have shown the effectiveness of community-based hypertension detection and care delivery models, their adoption and translation to practice has been slow. In this study, we will develop and test strategies …
View article: Investigating the contribution of socio-economic position to ethnic inequalities in severe COVID-19 outcomes: population-based mediation analyses of national linked Scottish data
Investigating the contribution of socio-economic position to ethnic inequalities in severe COVID-19 outcomes: population-based mediation analyses of national linked Scottish data Open
We quantified the extent to which socio-economic position (SEP) contributed to ethnic inequalities in severe COVID-19 outcomes (hospitalization or death) in Scotland. We used linked 2011 Scottish Census and health records to assess whether…
View article: Exploring the disease experience and supportive care for people with very severe chronic obstructive pulmonary disease in Malaysia: a multiperspective qualitative study
Exploring the disease experience and supportive care for people with very severe chronic obstructive pulmonary disease in Malaysia: a multiperspective qualitative study Open
The Malaysian healthcare system is responding poorly to the needs of patients with very severe COPD. Raising awareness of these needs is the first step, but there needs to be a major change within the system if the care of this hidden negl…
View article: Unveiling Healthcare Disparities: Social Exclusion and Public Health Challenges in Rural Ganderbal, Kashmir
Unveiling Healthcare Disparities: Social Exclusion and Public Health Challenges in Rural Ganderbal, Kashmir Open
This study explores the dynamics of social exclusion in healthcare settings within the rural Ganderbal district of Kashmir, focusing on the availability of health facilities and the health-seeking behaviors of socially disadvantaged popula…
View article: Correction: Navigating the complexities of end-stage kidney disease (ESKD) from risk factors to outcome: insights from the UK Biobank cohort
Correction: Navigating the complexities of end-stage kidney disease (ESKD) from risk factors to outcome: insights from the UK Biobank cohort Open
View article: Socio-Demographic Factors Associated with Postpartum Depression Among Woman Delivering in Banadir hospital Mogadishu, Somalia
Socio-Demographic Factors Associated with Postpartum Depression Among Woman Delivering in Banadir hospital Mogadishu, Somalia Open
Background: Postpartum depression (PPD) is a significant global mental health issue, affecting 10-15% of women after childbirth. While its prevalence is well documented worldwide, the socio-demographic factors influencing PPD in Somalia re…
View article: Prevalence of Recreational Drug Use among Medical Student of Pakistan
Prevalence of Recreational Drug Use among Medical Student of Pakistan Open
This study investigated the prevalence of psychological distress, recreational drug use, and help-seeking behavior among 273 medical students from five institutions in Lahore, Pakistan. High levels of mental health issues were found using …
View article: Correction: Conducting tobacco control surveys among schoolchildren in Bangladesh, India and Pakistan: A feasibility study
Correction: Conducting tobacco control surveys among schoolchildren in Bangladesh, India and Pakistan: A feasibility study Open
[This corrects the article DOI: 10.1371/journal.pgph.0003784.].