Ahmad Alamer
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View article: DPP4 inhibitors and COVID19 outcomes in patients with type II diabetes: a multicenter retrospective cohort study in Saudi Arabia
DPP4 inhibitors and COVID19 outcomes in patients with type II diabetes: a multicenter retrospective cohort study in Saudi Arabia Open
Dipeptidyl peptidase-4 inhibitors (DPP-4is) have been hypothesized to impact COVID-19 outcomes by modulating immune and inflammatory responses. This study aimed to assess the association between DPP-4i use and COVID-19 severity in patients…
View article: Incidence and predictors of vancomycin nephrotoxicity and mortality in patients with chronic liver disease: a two-center retrospective cohort study
Incidence and predictors of vancomycin nephrotoxicity and mortality in patients with chronic liver disease: a two-center retrospective cohort study Open
Patients who had MSLD had a higher trough vancomycin levels and mortality than patients who had MLD; and this risk increases as liver disease progresses. Thus, the existence of chronic liver disease should be considered when monitoring tox…
View article: Public perception of COVID-19 in Saudi Arabia during the Omicron wave: recommendations for policy improvement
Public perception of COVID-19 in Saudi Arabia during the Omicron wave: recommendations for policy improvement Open
Background The emergence of new SARS-CoV-2 variants makes it difficult to forecast potential epidemiological changes. This study investigates Saudi citizens’ perceptions of COVID-19 during the Omicron wave. Methods We conducted a cross-sec…
View article: Predictors of Type-2 Diabetes Self-Screening: The Impact of Health Beliefs Model, Knowledge, and Demographics
Predictors of Type-2 Diabetes Self-Screening: The Impact of Health Beliefs Model, Knowledge, and Demographics Open
Background: Diabetes mellitus (DM) is a global health concern, and the intention to undergo diabetes self-screening among patients varies based on demographics and the Health Belief Model (HBM). Objective: This study aimed to identify the …
View article: Impact of Rapid Emergency Medical Services Response Times on Patient Outcomes in Saudi Arabia
Impact of Rapid Emergency Medical Services Response Times on Patient Outcomes in Saudi Arabia Open
Rapid Emergency Medical Services (EMS) response times play a crucial role in determining patient outcomes in Saudi Arabia, where the prevalence of acute medical conditions such as cardiac arrests, strokes, and trauma cases is significant. …
View article: A novel role for nonactin: interfering with G-quadruplex in RET-driven medullary thyroid cancer
A novel role for nonactin: interfering with G-quadruplex in RET-driven medullary thyroid cancer Open
View article: Factors Affecting Vancomycin Trough Concentration; a Population Pharmacokinetic Model in Non-Critical Care Saudi Patients
Factors Affecting Vancomycin Trough Concentration; a Population Pharmacokinetic Model in Non-Critical Care Saudi Patients Open
This study highlights large BSV in trough concentrations among patients and emphasizes the influencing of CrCl and CRP on vancomycin pharmacokinetics in medical care settings.
View article: Short term effectiveness of ustekinumab versus vedolizumab in Crohn’s disease after failure of anti-TNF agents: An observational comparative study design with a Bayesian analysis
Short term effectiveness of ustekinumab versus vedolizumab in Crohn’s disease after failure of anti-TNF agents: An observational comparative study design with a Bayesian analysis Open
Background: Crohn’s disease (CD) is a debilitating gastrointestinal disease with complex etiology. Although effective, recipients of anti-tumor necrosis factor (TNF) agents may experience primary or secondary nonresponse, necessitating alt…
View article: Prescribing patterns and persistence of biological therapies for psoriasis management: a retrospective cohort study from Saudi Arabia
Prescribing patterns and persistence of biological therapies for psoriasis management: a retrospective cohort study from Saudi Arabia Open
This study shows changing psoriasis treatment patterns with new therapies. Risankizumab demonstrated high long-term persistence, while etanercept and ustekinumab showed declining persistence, suggesting evolving treatment considerations.
View article: Insight into Current Practices of Community Pharmacists in Topical Corticosteroid Prescribing and Counseling: Cross-Sectional Survey Study from Saudi Arabia
Insight into Current Practices of Community Pharmacists in Topical Corticosteroid Prescribing and Counseling: Cross-Sectional Survey Study from Saudi Arabia Open
Background: Topical corticosteroids are commonly used to treat several skin conditions, most notably atopic dermatitis. Many studies have found that patients lack knowledge about the safety, potency, and appropriate use of topical corticos…
View article: Incidence Rate of Cardiovascular Events in Rheumatoid Arthritis: An Observational Cohort Study in Saudi Arabia
Incidence Rate of Cardiovascular Events in Rheumatoid Arthritis: An Observational Cohort Study in Saudi Arabia Open
This unique study from SA examined the CVD incidence in RA patients, identifying long disease duration and male gender as significant predictors. Effective reduction of CVD risk in RA patients requires aggressive management of modifiable r…
View article: Endogenous bacterial endophthalmitis in an HIV patient with uncontrolled diabetes: A case of rare ocular complication
Endogenous bacterial endophthalmitis in an HIV patient with uncontrolled diabetes: A case of rare ocular complication Open
Endogenous bacterial endophthalmitis (EE) is an intraocular infection with a poor prognosis. Timely diagnosis and prompt treatment are crucial to prevent vision loss. In this communication, we describe a case of EE caused by Streptococcus …
View article: Evaluation of Serial Procalcitonin Levels for the Optimization of Antibiotic Use in Non-Critically Ill COVID-19 Patients
Evaluation of Serial Procalcitonin Levels for the Optimization of Antibiotic Use in Non-Critically Ill COVID-19 Patients Open
Background: Procalcitonin (PCT) has been used as a biomarker to guide antibiotic therapy in various patient populations. However, its role in optimizing antibiotic use in COVID-19 patients has not been well studied to date. Thus, we aimed …
View article: Association between COVID-19 severity and tobacco smoking status: a retrospective cohort study using propensity score matching weights analysis
Association between COVID-19 severity and tobacco smoking status: a retrospective cohort study using propensity score matching weights analysis Open
Introduction The COVID-19 pandemic continues to be a global threat to public health, with over 766 million confirmed cases and more than 6 million reported deaths. Patients with a smoking history are at a greater risk of severe respiratory…
View article: The Association between Self-Care Activities and Depression in Adult Patients with Type 2 Diabetes in Saudi Arabia: A Cross-Sectional Web-Based Survey Study
The Association between Self-Care Activities and Depression in Adult Patients with Type 2 Diabetes in Saudi Arabia: A Cross-Sectional Web-Based Survey Study Open
This study examined the level of adherence to self-care behaviors among individuals with type 2 diabetes in Saudi Arabia and its connection with depression and demographic factors. A cross-sectional survey was conducted among diabetes pati…
View article: P688 Comparative Effectiveness of Ustekinumab Versus Vedolizumab in Treating Crohn’s Disease After Failure of Anti-TNF Agents: Real-World Evidence
P688 Comparative Effectiveness of Ustekinumab Versus Vedolizumab in Treating Crohn’s Disease After Failure of Anti-TNF Agents: Real-World Evidence Open
Background Despite effective anti-TNF agents in treating Crohn’s disease (CD), some recipients experience primary or secondary non-responses, requiring alternative options. Ustekinumab and vedolizumab have not been compared in randomized c…
View article: P1020 Developing and Validating a Clinical Prediction Model Using Biomarkers to Assess Clinical Response and Severity of Crohn's Disease 12 Weeks After Initiation of Biological Therapy
P1020 Developing and Validating a Clinical Prediction Model Using Biomarkers to Assess Clinical Response and Severity of Crohn's Disease 12 Weeks After Initiation of Biological Therapy Open
Background Despite the evolution of therapeutic strategies for Crohn’s disease (CD), many patients exhibit resistance to numerous biological agents, necessitating a transition to other advanced therapies. Therefore, the early and accurate …
View article: The influence of telemedicine in primary healthcare on diabetes mellitus control and treatment adherence in Riyadh region
The influence of telemedicine in primary healthcare on diabetes mellitus control and treatment adherence in Riyadh region Open
Several studies have found that telemedicine has the potential to enhance the outcomes of patients with diabetes. This study aimed to determine the impact of telemedicine on the clinical outcomes of patients with type 2 diabetes mellitus (…
View article: Amentoflavone Mitigates Cyclophosphamide-Induced Pulmonary Toxicity: Involvement of -SIRT-1/Nrf2/Keap1 Axis, JAK-2/STAT-3 Signaling, and Apoptosis
Amentoflavone Mitigates Cyclophosphamide-Induced Pulmonary Toxicity: Involvement of -SIRT-1/Nrf2/Keap1 Axis, JAK-2/STAT-3 Signaling, and Apoptosis Open
Background and objectives: Cyclophosphamide (CPA) is an alkylating agent that is used for the management of various types of malignancies and as an immunosuppressive agent for the treatment of immunological disorders. However, its use is l…
View article: Access and Disparities in the Use of Telemedicine Among Patients with Chronic Conditions in Saudi Arabia: A Cross-Sectional Study
Access and Disparities in the Use of Telemedicine Among Patients with Chronic Conditions in Saudi Arabia: A Cross-Sectional Study Open
This study highlights a significant disparity in the utilization of telemedicine services across different populations, primarily due to demographic and socioeconomic factors.
View article: The clinical impact of rifampicin-based anti-TB therapy and tenofovir alafenamide-containing ARV regimen drug Interaction in people living with HIV: Case series report
The clinical impact of rifampicin-based anti-TB therapy and tenofovir alafenamide-containing ARV regimen drug Interaction in people living with HIV: Case series report Open
A total of 7 PLWH who met the inclusion criteria, 5 (71 %) out of 7, were males. All patients received dolutegravir 50 mg twice daily (DTG) plus the combination of TAF 25 mg and emtricitabine 200 mg (FTC) once daily as their ARV regimen. F…
View article: Knowledge, perceptions, and readiness of telepharmacy among community pharmacists
Knowledge, perceptions, and readiness of telepharmacy among community pharmacists Open
Telepharmacy is a practical part of telemedicine that refers to providing pharmaceutical services within the scope of the pharmacist's obligations while maintaining a temporal and spatial distance between patients, users of health services…
View article: Knowledge, Perceptions, and Readiness of Telepharmacy among Hospital Pharmacists in Saudi Arabia
Knowledge, Perceptions, and Readiness of Telepharmacy among Hospital Pharmacists in Saudi Arabia Open
Telepharmacy is a technology-based service that provides promoted services such as counseling, medication administration and compounding, drug therapy monitoring, and prescription review. It is unclear whether hospital pharmacists possess …
View article: Quality of life and tomography indices in patients with keratoconus
Quality of life and tomography indices in patients with keratoconus Open
Objective Keratoconus is a corneal ectasia that leads to thinning and steepening of the corneal surface. We aimed to assess the relationship between quality of life and corneal tomography indices, irrespective of visual acuity. Methods Thi…
View article: Types, trends, and patterns of the reported antimicrobial errors to the eastern region’s medical centers in Saudi Arabia: A cross-sectional study
Types, trends, and patterns of the reported antimicrobial errors to the eastern region’s medical centers in Saudi Arabia: A cross-sectional study Open
This study revealed that antimicrobial errors occur primarily during prescription and that policy gaps and inexperienced staff were contributory factors. To improve, the focus should shift to physician education, clear dosing guidelines, e…
View article: Cost-effectiveness of Favipiravir in moderately to severely ill COVID-19 patients in the real-world setting of Saudi arabian pandemic referral hospitals
Cost-effectiveness of Favipiravir in moderately to severely ill COVID-19 patients in the real-world setting of Saudi arabian pandemic referral hospitals Open
View article: Prevalence and Associations of Type 2 Diabetes Risk and Sociodemographic Factors in Saudi Arabia: A Web-Based Cross-Sectional Survey Study
Prevalence and Associations of Type 2 Diabetes Risk and Sociodemographic Factors in Saudi Arabia: A Web-Based Cross-Sectional Survey Study Open
Type 2 diabetes mellitus (T2DM) is a chronic disease with ever-increasing prevalence worldwide. In our study, we evaluated the prevalence of the risk of developing T2DM in Saudi Arabia and investigated associations between that risk and va…
View article: Assessing tobramycin levels and renal function following the implantation of CaSO4 beads impregnated with tobramycin: A prospective cohort study
Assessing tobramycin levels and renal function following the implantation of CaSO4 beads impregnated with tobramycin: A prospective cohort study Open
This study aimed to evaluate the risk of serum tobramycin concentrations exceeding therapeutic levels after administration of calcium sulfate (CaSO 4 ) beads containing either 240 mg or 400 mg tobramycin and 1000 mg vancomycin. This single…
View article: The Clinical Impact of Switching Basal Insulin to Insulin Degludec in Patients With Diabetes in Saudi Arabia: A Retrospective One-Group Pretest-Posttest Design Study
The Clinical Impact of Switching Basal Insulin to Insulin Degludec in Patients With Diabetes in Saudi Arabia: A Retrospective One-Group Pretest-Posttest Design Study Open
Switching to the novel insulin degludec conferred better blood glucose control and dose reduction. There was no increase in the frequency of hypoglycemic episodes or body weight.
View article: 1281. Rifampicin and Tenofovir Alafenamide Containing Regimen Drug Interaction in People Living with HIV: Case Series Report
1281. Rifampicin and Tenofovir Alafenamide Containing Regimen Drug Interaction in People Living with HIV: Case Series Report Open
Background Owing to the excellent safety and efficacy profile of the tenofovir alafenamide (TAF) over tenofovir disoproxil fumarate (TDF), it is the preferred prodrug of tenofovir (TFV) implicated in the management of people living with HI…