Ahmad Faizal Abdull Razis
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View article: Untargeted ¹H NMR Metabolomics of Elephantopus Scaber Reveals Correlation with Anti-Vibrio Activity
Untargeted ¹H NMR Metabolomics of Elephantopus Scaber Reveals Correlation with Anti-Vibrio Activity Open
View article: Application of Chitosan and Pectin‐Based Nanoemulsion Coating for the Preservation of Plum ( <i>Prunus domestica</i> ) Fruit
Application of Chitosan and Pectin‐Based Nanoemulsion Coating for the Preservation of Plum ( <i>Prunus domestica</i> ) Fruit Open
Pectin, a bioactive polysaccharide, was mixed with chitosan (CS) and blended with three essential oil formulations to prepare nanoemulsion‐based edible coatings. Three nanoemulsion‐based coatings, C 1 , C 2 , and C 3 , comprising chitosan …
View article: Recent progress in calcium carbonate nanoparticles for cancer therapy: design strategies and clinical prospects
Recent progress in calcium carbonate nanoparticles for cancer therapy: design strategies and clinical prospects Open
Calcium carbonate nanoparticles (CaCO 3 NPs) have garnered broad attention as promising nanocarriers for cancer therapy owing to their biocompatibility, pH sensitivity, ease of synthesis, and tunable surface properties. These NPs remain st…
View article: High-pressure processing (HPP) impacts on indian mackerel meat: insights into quality attributes, β-parvalbumin antigenicity, and proteomic changes
High-pressure processing (HPP) impacts on indian mackerel meat: insights into quality attributes, β-parvalbumin antigenicity, and proteomic changes Open
High-pressure processing (HPP) is a non-thermal method that uses high hydrostatic pressure on food products to improve quality and shelf life. However, it can cause structural changes in proteins that alter food characteristics. This study…
View article: Cardio- and neuroprotective effects by pretreatment of dietary moringin from <i>Moringa oleifera</i> seeds and α-CD/moringin formulation in a rat model of isoproterenol-induced myocardial infarction
Cardio- and neuroprotective effects by pretreatment of dietary moringin from <i>Moringa oleifera</i> seeds and α-CD/moringin formulation in a rat model of isoproterenol-induced myocardial infarction Open
The aim of this study was to investigate the cardio- and neuroprotective effects of moringin (MG), a dietary isothiocyanate readily derived from Moringa oleifera seed, in a rat model of isoproterenol (ISP) induced myocardial infarction (MI…
View article: Synthesis and Characterization of 5-Fluoroacil Loaded Calcium Carbonate Nanoparticles for Targeted Cancer Therapy
Synthesis and Characterization of 5-Fluoroacil Loaded Calcium Carbonate Nanoparticles for Targeted Cancer Therapy Open
Chemotherapy is often limited by its systemic toxicity and lack of specificity, necessitating the development of targeted drug delivery systems that can enhance therapeutic efficacy while minimizing adverse effects. Addressing this, our s…
View article: A review of emerging techniques for pyrethroid residue detection in agricultural commodities
A review of emerging techniques for pyrethroid residue detection in agricultural commodities Open
Pyrethroid pesticides are essential for modern agriculture, helping to control pests and protect crops. However, due to growing concerns about their potential impact on human health and the environment, reliable detection methods are essen…
View article: Microencapsulation of bioactive volatile compounds from MD2 pineapple peel Extract using spray-drying and foam-mat drying
Microencapsulation of bioactive volatile compounds from MD2 pineapple peel Extract using spray-drying and foam-mat drying Open
Pineapple peel extracts constitute bioactive compounds that degrade due to light, oxidation, and moisture. This study aimed to encapsulate cellulase-treated MD2 pineapple peel extracts ensuring stability of bioactive compounds-rich extract…
View article: Comprehensive Insights Into the Combinatorial Uses of Selected Phytochemicals in Colorectal Cancer Prevention and Treatment: Isothiocyanates, Quinones, Carotenoids, and Alkaloids
Comprehensive Insights Into the Combinatorial Uses of Selected Phytochemicals in Colorectal Cancer Prevention and Treatment: Isothiocyanates, Quinones, Carotenoids, and Alkaloids Open
Despite the advancement in cancer diagnosis and treatment, colorectal cancer remains the leading cause of cancer‐related death worldwide. Given the high recurrence rate of colorectal cancer even after surgical resection, chemotherapy has b…
View article: Identification and validation of novel breed-specific biomarker for the purpose of village chicken authentication using genomics approaches
Identification and validation of novel breed-specific biomarker for the purpose of village chicken authentication using genomics approaches Open
View article: Ceramic Hydroxyapatite Derived from Fish Scales in Biomedical Applications: a Systematic Review
Ceramic Hydroxyapatite Derived from Fish Scales in Biomedical Applications: a Systematic Review Open
The production of fish waste is increasing dramatically, as more than 70% of captured fish require processing before being sold. These enormous amounts of fish by-products are mostly wasted, generating an undesirable environmental impact …
View article: WITHDRAWN: Application of chitosan and clove oil-based nanoemulsion extending the postharvest preservation of strawberry fruit at various temperatures
WITHDRAWN: Application of chitosan and clove oil-based nanoemulsion extending the postharvest preservation of strawberry fruit at various temperatures Open
In this study, an edible-coating nanoemulsion was formulated by combining chitosan (CS) with clove essential oil (CEO). The resulting nanoemulsion exhibited desirable physical characteristics, including a particle size of 99 ± 2.3 nm, a ζ-…
View article: Development of microbial desalination cells for the treatment of reverse osmosis reject water: A new benchtop approach
Development of microbial desalination cells for the treatment of reverse osmosis reject water: A new benchtop approach Open
To address the growing global demand for usable water, there is an immediate necessity to enhance wastewater treatment systems. A continuous mode adaption of the conventional three-chamber microbial desalination cell (MDC) configuration wa…
View article: Mycotoxin patulin contamination in various fruits and estimating its dietary impact on the consumers: From orchard to table
Mycotoxin patulin contamination in various fruits and estimating its dietary impact on the consumers: From orchard to table Open
The present research examined patulin's presence across the whole supply chain of selected fruits. A comprehensive analysis was conducted on 442 samples of fruits (oranges, apples, apricots, lemons, and guava) to determine the presence of …
View article: Proanthocyanidins supplemented diet alter anti-aging-markers and improved lifespan in Drosophila melanogaster model
Proanthocyanidins supplemented diet alter anti-aging-markers and improved lifespan in Drosophila melanogaster model Open
Background It is unequivocally believed that phenolics and flavonoids from fruits and vegetables hold robust prevention potentials against age-related disease development through their abundant hydroxyl groups. This study explored the pote…
View article: Antiallergic Effect of the Alpha‐Cyclodextrin Moringin Complex in Rat Basophilic Leukaemia (RBL‐2H3) Cell Line
Antiallergic Effect of the Alpha‐Cyclodextrin Moringin Complex in Rat Basophilic Leukaemia (RBL‐2H3) Cell Line Open
Allergic diseases (ADs) are a major concern when it comes to public well‐being. Moringa oleifera Lam is a tropical plant that is used in traditional medicine due to the presence of isothiocyanate. The present study investigated the antiall…
View article: In-silico Prediction Analysis of Polyphenolic Contents of Ethanolic Extract of Moringa oleifera Leaves
In-silico Prediction Analysis of Polyphenolic Contents of Ethanolic Extract of Moringa oleifera Leaves Open
Introduction: Moringa oleifera is widely consumed as a source of nutrients and as traditional medicine for treating myriads of diseases in Southeast Asia, Africa, and South America. Polyphenols are abundantly found in the leaves of Moringa…
View article: Anti-cancer properties of boswellic acids: mechanism of action as anti-cancerous agent
Anti-cancer properties of boswellic acids: mechanism of action as anti-cancerous agent Open
With the advent of highly effective plant-based medications with few or no side effects, the use of phytomedicines against complex diseases such as cancer is becoming more widespread. The broadly recognized pentacyclic triterpenes known as…
View article: Anticancer properties of sulforaphane: current insights at the molecular level
Anticancer properties of sulforaphane: current insights at the molecular level Open
Sulforaphane (SFN) is an isothiocyanate with multiple biomedical applications. Sulforaphane can be extracted from the plants of the genus Brassica . However, broccoli sprouts are the chief source of sulforaphane and are 20 to 50 times rich…
View article: Neopeltolide and its synthetic derivatives: a promising new class of anticancer agents
Neopeltolide and its synthetic derivatives: a promising new class of anticancer agents Open
Being the first or second cause of death worldwide, cancer represents the most significant clinical, social, and financial burden of any human illness. Despite recent progresses in cancer diagnosis and management, traditional cancer chemot…
View article: Medicinal and mechanistic overview of artemisinin in the treatment of human diseases
Medicinal and mechanistic overview of artemisinin in the treatment of human diseases Open
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial infections, and some cardiovascular diseases, especi…
View article: Oxidative stress, free radicals and antioxidants: potential crosstalk in the pathophysiology of human diseases
Oxidative stress, free radicals and antioxidants: potential crosstalk in the pathophysiology of human diseases Open
Introduction: Free radicals are reactive oxygen species that constantly circulate through the body and occur as a side effect of many reactions that take place in the human body. Under normal conditions, they are removed from the body by a…
View article: Exploring the therapeutic and anti-tumor properties of morusin: a review of recent advances
Exploring the therapeutic and anti-tumor properties of morusin: a review of recent advances Open
Morusin is a natural product that has been isolated from the bark of Morus alba , a species of mulberry tree. It belongs to the flavonoid family of chemicals, which is abundantly present in the plant world and is recognized for its wide ra…
View article: An updated overview of cyanidins for chemoprevention and cancer therapy
An updated overview of cyanidins for chemoprevention and cancer therapy Open
Anthocyanins are colored polyphenolic compounds that belong to the flavonoids family and are largely present in many vegetables and fruits. They have been used in traditional medicine in many cultures for a long time. The most common and a…
View article: 7-Geranyloxycinnamic Acid Isolated from Melicope lunu-ankenda Leaves Perturbs Colon Cancer and Breast Cancer Cell Lines’ Growth via Induction of Apoptotic Pathway
7-Geranyloxycinnamic Acid Isolated from Melicope lunu-ankenda Leaves Perturbs Colon Cancer and Breast Cancer Cell Lines’ Growth via Induction of Apoptotic Pathway Open
Globally, breast cancer is the most prevalent form of cancer in women and there is a need for alternative therapies such as plant-derived compounds with low systemic toxicity and selective toxicity to cancer cells. The aim of this study is…
View article: Phytates as a natural source for health promotion: A critical evaluation of clinical trials
Phytates as a natural source for health promotion: A critical evaluation of clinical trials Open
Phytates are a type of organophosphorus compound produced in terrestrial ecosystems by plants. In plant feeds, phytic acid and its salt form, phytate, account for 60%–80% of total phosphorus. Because phytate is a polyanionic molecule, it c…
View article: Spermidine as a promising anticancer agent: Recent advances and newer insights on its molecular mechanisms
Spermidine as a promising anticancer agent: Recent advances and newer insights on its molecular mechanisms Open
Spermidine is a naturally occurring polyamine compound found in semen. It is also found in several plant sources and boasts a remarkable biological profile, particularly with regards to its anticancer properties. Spermidine specifically in…
View article: Apoptotic Potential of Glucomoringin Isothiocyanate (GMG-ITC) Isolated from Moringa oleifera Lam Seeds on Human Prostate Cancer Cells (PC-3)
Apoptotic Potential of Glucomoringin Isothiocyanate (GMG-ITC) Isolated from Moringa oleifera Lam Seeds on Human Prostate Cancer Cells (PC-3) Open
Inhibition of several protein pathways involved in cancer cell regulation is a necessary key in the discovery of cancer chemotherapy. Moringa oleifera Lam is often used in traditional medicine for the treatment of various illnesses. The pl…
View article: An updated overview of anticancer effects of alternariol and its derivatives: underlying molecular mechanisms
An updated overview of anticancer effects of alternariol and its derivatives: underlying molecular mechanisms Open
Alternariol is a toxic metabolite of Alternaria fungi and studies have shown multiple potential pharmacological effects. To outline the anticancer effects and mechanisms of alternariol and its derivatives based on database reports, an upda…
View article: Impact of Processing Techniques on Deoxynivalenol Concentrations in Corn: A Journey from Grain to Bread
Impact of Processing Techniques on Deoxynivalenol Concentrations in Corn: A Journey from Grain to Bread Open