Nor Hadiani Ismail
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View article: In vitro Cytoprotective Effects of Pluchea indica L. Leaf Extract on Vero Cells against Oxidative Stress: A Comparative Study of Preventive and Curative Treatments
In vitro Cytoprotective Effects of Pluchea indica L. Leaf Extract on Vero Cells against Oxidative Stress: A Comparative Study of Preventive and Curative Treatments Open
View article: Uncaria nervosa Elmer, a new herbal source for betulinic acid and ursolic acid: Metabolites profiling, isolation, and in vitro cytotoxicity studies against T47D breast cancer
Uncaria nervosa Elmer, a new herbal source for betulinic acid and ursolic acid: Metabolites profiling, isolation, and in vitro cytotoxicity studies against T47D breast cancer Open
Background Uncaria nervosa Elmer is an Indonesian herbal plant that is traditionally used for breast cancer. The results of phytochemical screening contained alkaloids, flavonoids, and terpenoids in the ethanol extract of this plant. Based…
View article: Racial and Ethnic Differences in Hirsutism Among Women with Polycystic Ovary Syndrome (PCOS): A narrative review
Racial and Ethnic Differences in Hirsutism Among Women with Polycystic Ovary Syndrome (PCOS): A narrative review Open
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women, frequently accompanied by hirsutism—a clinical marker of hyperandrogenism. However, the expression and diagnostic thresholds for hirsutism vary significantly acro…
View article: Phytochemical composition, antioxidant potential, and antimicrobial applications of ecoenzymes: A comprehensive review
Phytochemical composition, antioxidant potential, and antimicrobial applications of ecoenzymes: A comprehensive review Open
The increasing resistance to synthetic antimicrobial and the need for sustainable waste management solutions have led to the exploration of ecoenzymes as an alternative. Ecoenzymes, produced through the fermentation of organic waste such a…
View article: IMPLEMENTASI PERAWATAN VULVA HYGIENE PADA IBU NIFAS DI RUANGAN PERAWATAN NIFAS DI RSIA PERTIWI MAKASSAR
IMPLEMENTASI PERAWATAN VULVA HYGIENE PADA IBU NIFAS DI RUANGAN PERAWATAN NIFAS DI RSIA PERTIWI MAKASSAR Open
Post partum merupakan masa dimulai setelah kelahiran plasenta dan berakhir ketika alat kandungan kembali semula sepertisebelum hamil, yang berlangsung selama 6 minggu atau 42 hari. Selama periode pemulihan ini, ibu post partum akanmengalam…
View article: Anti-inflammatory Potential of Vernonia amygdalina Delile Extract: In Vitro Studies
Anti-inflammatory Potential of Vernonia amygdalina Delile Extract: In Vitro Studies Open
Vernonia amygdalina, commonly known as bitter leaf, widely used in traditional medicine across Africa and Asia, and is characterized by its bitter taste due to the presence of bioactive compounds such as flavonoids, alkaloids, saponins, an…
View article: NAVIGATING THE CHALLENGES OF AGING: A CONCEPTUAL ANALYSIS OF FINANCIAL STABILITY AND LIVELIHOOD SURVIVAL
NAVIGATING THE CHALLENGES OF AGING: A CONCEPTUAL ANALYSIS OF FINANCIAL STABILITY AND LIVELIHOOD SURVIVAL Open
Malaysia is experiencing a rapid demographic transition, with its aging population projected to rise significantly, from 8.1% in 2024 to 14.5% in 2040. This shift poses critical challenges to ensuring financial stability and livelihood sur…
View article: Primary pericardial sarcoma: contribution of cardiac MRI to diagnosis with early recurrence—a case report
Primary pericardial sarcoma: contribution of cardiac MRI to diagnosis with early recurrence—a case report Open
Pericardial sarcomas are rare malignant tumors with a poor prognosis. Imaging, particularly cardiac MRI, plays a central role in their initial evaluation and post-treatment follow-up. We present the case of a patient who underwent surgery …
View article: Uncaria nervosa Elmer, a new herbal source for betulinic acid and ursolic acid: Metabolites profiling, isolation, and in vitro cytotoxicity studies against T47D breast cancer
Uncaria nervosa Elmer, a new herbal source for betulinic acid and ursolic acid: Metabolites profiling, isolation, and in vitro cytotoxicity studies against T47D breast cancer Open
* Background Uncaria nervosa Elmer is an Indonesian herbal plant that is traditionally used for breast cancer. The results of phytochemical screening contained alkaloids, flavonoids, and terpenoids in the ethanol extract of this plant. Bas…
View article: Evaluation of Chemical Content and Phytochemical Composition of Yemeni Almond Cultivars
Evaluation of Chemical Content and Phytochemical Composition of Yemeni Almond Cultivars Open
The almond plant is considered one of the most important crops economically, nutritionally, and health-wise; its properties and chemical composition differ according to the places of its cultivation. This study aims to estimate the chemica…
View article: Potential protective effect of Panax ginseng extract on corticosteroid induced myopathy
Potential protective effect of Panax ginseng extract on corticosteroid induced myopathy Open
View article: BT30 Artificial intelligence triage is of greater benefit for screening suspected melanoma referrals than squamous cell carcinoma referrals
BT30 Artificial intelligence triage is of greater benefit for screening suspected melanoma referrals than squamous cell carcinoma referrals Open
There has been a rapid expansion in the use of artificial intelligence (AI) models to aid in diagnosis and triage of skin cancer in the UK in the last few years. This has been driven by a need to manage an increasing number of urgent refer…
View article: Evaluation of Chemical Content and Phytochemical Composition of Yemeni Almond Cultivars
Evaluation of Chemical Content and Phytochemical Composition of Yemeni Almond Cultivars Open
The almond plant is considered one of the most important agricultural crops economically, nutritionally, and healthily, its properties and chemical composition differ according to the places of its cultivation. This study aims to estimate …
View article: Chemical characterizations dataset of flavonoid glycoside isomers and other constituents from Ficus deltoidea Jack
Chemical characterizations dataset of flavonoid glycoside isomers and other constituents from Ficus deltoidea Jack Open
View article: 1H NMR metabolomics insights into comparative diabesity in male and female zebrafish and the antidiabetic activity of DL-limonene
1H NMR metabolomics insights into comparative diabesity in male and female zebrafish and the antidiabetic activity of DL-limonene Open
Zebrafish have been utilized for many years as a model animal for pharmacological studies on diabetes and obesity. High-fat diet (HFD), streptozotocin and alloxan injection, and glucose immersion have all been used to induce diabetes and o…
View article: Analysis of the Structure and the Anti-Inflammatory Effects of a New Compound from Garcinia Cowa Roxb
Analysis of the Structure and the Anti-Inflammatory Effects of a New Compound from Garcinia Cowa Roxb Open
View article: Data on LC–MS profile of Brucea javanica (L.) Merr. and the NMR data of its major indole alkaloids
Data on LC–MS profile of Brucea javanica (L.) Merr. and the NMR data of its major indole alkaloids Open
View article: OPTIMIZATION OF DEPROTEINIZATION METHODS, HPLC METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF 6Β-HYDROXYTESTOSTERONE IN CELL CULTURE MEDIA
OPTIMIZATION OF DEPROTEINIZATION METHODS, HPLC METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF 6Β-HYDROXYTESTOSTERONE IN CELL CULTURE MEDIA Open
Testosterone is commonly used as a marker probe drug for CYP3A4 metabolic activity. Accurate measurement of its metabolite, 6β-hydroxytestosterone in cell culture media is very crucial. This study aimed to optimize solvent extraction metho…
View article: Antimalarial and toxicological assessment of the tablet (AS201-01) ethyl acetate fraction of Andrographis paniculata Nees in animal models
Antimalarial and toxicological assessment of the tablet (AS201-01) ethyl acetate fraction of Andrographis paniculata Nees in animal models Open
Context: Andrographis paniculata has been used as a traditional medicine to treat malaria. The ethyl acetate fraction of A. paniculata containing diterpene lactone compounds was developed into a tablet dosage form, AS201-01. Aims: To deter…
View article: Antimalarial dihydrochalcone isolated from Artocarpus sericicarpus Jarret leaves and in silico investigation against falcipain-2 protein
Antimalarial dihydrochalcone isolated from Artocarpus sericicarpus Jarret leaves and in silico investigation against falcipain-2 protein Open
Aims: To investigate the potential antimalarial plant belonging to the Artocarpus genus, Artocarpus sericicarpus, and isolate the antimalarial active compound from leaves extract. Methods: The isolation of the antimalarial compound was bas…
View article: Lactic Acid Bacteria (LAB) and Neuroprotection, What Is New? An Up-To-Date Systematic Review
Lactic Acid Bacteria (LAB) and Neuroprotection, What Is New? An Up-To-Date Systematic Review Open
Background: In recent years, the potential role of probiotics has become prominent in the discoveries of neurotherapy against neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases. Lactic acid bacteria (LAB) exhibit neur…
View article: Ficus deltoidea var. kunstleri Extract Administration in Hypercholesterolaemic, Atherosclerotic Rabbits: Effects on Organ Function, Morphology, and Atherosclerosis Development
Ficus deltoidea var. kunstleri Extract Administration in Hypercholesterolaemic, Atherosclerotic Rabbits: Effects on Organ Function, Morphology, and Atherosclerosis Development Open
Ficus deltoidea (FD) is used in traditional Malay medicine to treat various ailments and has been shown to be safe in toxicity studies. However, the information on the safety and efficacy of FD in the atherosclerosis-induced animal model i…
View article: Cytotoxic Activity Screening of Various Uncaria Spp Plants on T47d Breast Cancer Cells
Cytotoxic Activity Screening of Various Uncaria Spp Plants on T47d Breast Cancer Cells Open
Breast cancer is a disease characterised by uncontrolled cell growth in breast cells. One of the plants known to have anticancer activity is a plant from Uncaria genus. Some of those found in Province "Riau", Indonesia include Uncaria barb…
View article: Isolation and Characterization of Compounds from Ochreinauclea maingayi (Hook. f.) Ridsd. (Rubiaceae) with the Aid of LCMS/MS Molecular Networking
Isolation and Characterization of Compounds from Ochreinauclea maingayi (Hook. f.) Ridsd. (Rubiaceae) with the Aid of LCMS/MS Molecular Networking Open
Phytochemical investigation of the dichloromethane crude extract from the bark of Ochreinauclea maingayi with the aid of LCMS/MS-based molecular networking guided the isolation and accelerated the elucidation of known and new indole alkalo…
View article: Steroidal Alkaloids From the Apocynaceae Family: Their Isolation and Biological Activity
Steroidal Alkaloids From the Apocynaceae Family: Their Isolation and Biological Activity Open
Steroidal alkaloids are derived from the steroid skeleton with one or two nitrogen atoms. They are widely distributed in tropical and subtropical regions and possess a range of biological activities. The structures of steroidal alkaloids a…
View article: The antibacterial effect of Plectranthus scutellarioides (L.) R.Br. leaves extract against bacteria associated with peri-implantitis
The antibacterial effect of Plectranthus scutellarioides (L.) R.Br. leaves extract against bacteria associated with peri-implantitis Open
Four flavonoid compounds were identified namely quercetin-3-glucoside, quercitrin, quercetin 3-(6″-acetylglucoside) and quercetin 3-O-acetyl-rhamnoside. The sensitivity test revealed that P. scutellarioides extract was effect…
View article: (<i>R</i>)-13a<i>α</i>-Densiindolizidine, A New Phenanthroindolizidine Alkaloid From <i>Cryptocarya densiflora</i> Blume (Lauraceae) and Molecular Docking Against SARS-CoV-2
(<i>R</i>)-13a<i>α</i>-Densiindolizidine, A New Phenanthroindolizidine Alkaloid From <i>Cryptocarya densiflora</i> Blume (Lauraceae) and Molecular Docking Against SARS-CoV-2 Open
Cryptocarya densiflora Blume (Lauraceae) is an evergreen tree widely distributed throughout the hills and mountain forests up to 1500 m in Malaysia and Indonesia. The plant has been reported to contain phenanthroindolizidine-type of alkalo…
View article: ACUTE ORAL TOXICITY STUDY OF ROOT METHANOL EXTRACT OF Goniothalamus lanceolatus Miq. AND ITS ISOLATED BIOACTIVE COMPOUND (PARVISTONE D) IN MURINE MODEL
ACUTE ORAL TOXICITY STUDY OF ROOT METHANOL EXTRACT OF Goniothalamus lanceolatus Miq. AND ITS ISOLATED BIOACTIVE COMPOUND (PARVISTONE D) IN MURINE MODEL Open
Goniothalamus lanceolatus Miq. is widely used by the indigenous people of Sarawak, Malaysia as a folk remedy to treat various ailments including skin diseases, cold, and fever. A previous study reported that the root methanol extract, and …
View article: Dichloromethane stem bark extract of Goniothalamus lanceolatus Miq. modulates inflammatory cytokines and ameliorates tissue damage in Plasmodium berghei-infected mice
Dichloromethane stem bark extract of Goniothalamus lanceolatus Miq. modulates inflammatory cytokines and ameliorates tissue damage in Plasmodium berghei-infected mice Open
Goniothalamus lanceolatus extract inhibits the growth of human ovarian cancer cells through migration suppression and apoptosis inductionNasibah Razali, Norodiyah Othman, Nur Hilwani Ismail, Nur Vicky Bihud, Nor Hadiani Ismail, Farida Zura…
View article: Centella Asiatica (L.) Urb. Extract Ameliorates Branched-Chain Amino Acid (BCAA) Metabolism in Acute Reserpine-Induced Stress Zebrafish Model Via 1h Nuclear Magnetic Resonance (NMR)-Based Metabolomics Approach
Centella Asiatica (L.) Urb. Extract Ameliorates Branched-Chain Amino Acid (BCAA) Metabolism in Acute Reserpine-Induced Stress Zebrafish Model Via 1h Nuclear Magnetic Resonance (NMR)-Based Metabolomics Approach Open