Mohammad Ahmad
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View article: A Site-Specific Self-Association of a Protein Hub Drives Its Phase Separation
A Site-Specific Self-Association of a Protein Hub Drives Its Phase Separation Open
Liquid-liquid phase separation (LLPS) is pivotal in generating membraneless organelles and assembling cellular inclusions. Interactions mediated by RNA and intrinsically disordered regions of proteins are ubiquitous mechanisms that drive t…
View article: Knowledge, Attitudes, and Practices Regarding Antibiotic Use and Resistance Among the General Adult Population in Riyadh Province, Saudi Arabia
Knowledge, Attitudes, and Practices Regarding Antibiotic Use and Resistance Among the General Adult Population in Riyadh Province, Saudi Arabia Open
Background Antibiotic resistance has become a global concern, contributing to significant morbidity and mortality. The prominent cause of antibiotic resistance remains the overuse and inappropriate use of antibiotics. This study aimed to e…
View article: Secure and Fault-Tolerant IoT-Based Healthcare System for Reliable Decision-Making
Secure and Fault-Tolerant IoT-Based Healthcare System for Reliable Decision-Making Open
Internet of Things (IoT) integration has revolutionized healthcare, offering personalized medical care through remote patient monitoring and telemedicine. However, challenges remain in critical healthcare scenarios, such as data security v…
View article: Enforcing Extra Behavioral Activity in Spinal Cord-Injured Rats Can Be a Rehabilitation Process to Enhance the Effects of Pentoxifylline and Tacrolimus Treatment: A Nursing Care Perspective
Enforcing Extra Behavioral Activity in Spinal Cord-Injured Rats Can Be a Rehabilitation Process to Enhance the Effects of Pentoxifylline and Tacrolimus Treatment: A Nursing Care Perspective Open
Background: Pentoxifylline and Tacrolimus are known to improve the functional outcome of spinal cord injury (SCI). The present study aims to develop suitable rehabilitative interventions in conjunction with therapeutic agents to enhance fu…
View article: Identification of Potential Biomarkers and Pathways in Acute Myeloid Leukemia: Correlation Between the Calcineurin Signaling Pathway and Vascular Brittleness in Acute Myeloid Leukemia
Identification of Potential Biomarkers and Pathways in Acute Myeloid Leukemia: Correlation Between the Calcineurin Signaling Pathway and Vascular Brittleness in Acute Myeloid Leukemia Open
Objective In this study, clinical bioinformatics analysis was used to identify potential biomarkers of acute myeloid leukemia (AML) occurrence and development, drug resistance, and poor prognosis to provide a theoretical basis for the trea…
View article: Analysis of antidiabetic drug utilization patterns in type 2 diabetes patients: a perspective on real-time prescribing practices
Analysis of antidiabetic drug utilization patterns in type 2 diabetes patients: a perspective on real-time prescribing practices Open
Background: Type 2 diabetes is a most common health problem associated with significant morbidity and mortality worldwide, evaluation of drug utilization pattern is very crucial and significant in order to promote the rational use of drugs…
View article: Real-Time Measurement of a Weak Interaction of a Transcription Factor Motif with a Protein Hub at Single-Molecule Precision
Real-Time Measurement of a Weak Interaction of a Transcription Factor Motif with a Protein Hub at Single-Molecule Precision Open
Transcription factors often interact with other protein cofactors, regulating gene expression. Direct detection of these brief events using existing technologies remains challenging due to their transient nature. In addition, intrinsically…
View article: Multiple Myeloma: A Personal Account of My Journey With the Disease and Response to Teclistamab
Multiple Myeloma: A Personal Account of My Journey With the Disease and Response to Teclistamab Open
Multiple myeloma (MM) remains an incurable hematologic cancer leading to damage to the bone marrow that causes destructive bone lesions in addition to many other effects. I am a patient with MM who has undergone treatment to date since the…
View article: Exploring the prognostic significance of β-HCG levels in cervicovaginal secretionsand maternal risk factors for early birth
Exploring the prognostic significance of β-HCG levels in cervicovaginal secretionsand maternal risk factors for early birth Open
Preterm birth is one of the leading causes of death in the perinatal period, this study was conducted to investigate the predictive value of β-HCG Levels in cervicovaginal secretions and maternal risk factors in preterm delivery. This cros…
View article: Comparative protective evaluation of curcumin and nano curcumin on the oxidative stress and other indices in the blood of experimental status epilepticus animal model
Comparative protective evaluation of curcumin and nano curcumin on the oxidative stress and other indices in the blood of experimental status epilepticus animal model Open
Background: Curcumin possesses antioxidant properties against oxidative damage, exerting powerful oxygen-free radical scavenging effects. The present study compares the protective effects of pre-treatment with curcumin and nanoparticles of…
View article: Psychometric Testing Designed to Assess the Knowledge, Healthcare Awareness and Perceptions About Epilepsy Among College Students
Psychometric Testing Designed to Assess the Knowledge, Healthcare Awareness and Perceptions About Epilepsy Among College Students Open
Epilepsy is characterized by recurrent seizures, which are brief episodes of involuntary movement that may involve a part of the body or the entire body.This study aims at estimating the level of knowledge, healthcare awareness and percept…
View article: Long non-coding RNA NEAT1 inhibits high glucose-induced EMT and renal fibrogenesis in Human Embryonic Kidney 293 cells via regulating miR-204/SOX4 axis
Long non-coding RNA NEAT1 inhibits high glucose-induced EMT and renal fibrogenesis in Human Embryonic Kidney 293 cells via regulating miR-204/SOX4 axis Open
Diabetic nephropathy (DN) is a severe complication of diabetes that increases mortality worldwide. Long non-coding RNAs (lncRNAs) have been investigated in DN, but the precise molecular mechanism is unclear. The research aimed to study the…
View article: Evaluation of Nanopore Sensor Design Using Electrical and Optical Analyses
Evaluation of Nanopore Sensor Design Using Electrical and Optical Analyses Open
Nanopores are currently utilized as powerful tools for single-molecule protein sensing. The reporting signal typically requires protein analytes to enter the nanopore interior, yet a class of these sensors has emerged that allows targeted …
View article: A generalizable nanopore sensor for highly specific protein detection at single-molecule precision
A generalizable nanopore sensor for highly specific protein detection at single-molecule precision Open
Protein detection has wide-ranging implications in molecular diagnostics. Substantial progress has been made in protein analytics using nanopores and the resistive-pulse technique. Yet, a long-standing challenge is implementing specific in…
View article: A Generalizable Nanopore Sensor for Highly Specific Protein Detection at Single-Molecule Precision
A Generalizable Nanopore Sensor for Highly Specific Protein Detection at Single-Molecule Precision Open
Protein detection and biomarker profiling have wide-ranging implications in many areas of basic research and molecular diagnostics. Substantial progress has been made in protein analytics using nanopores and the resistive-pulse technique. …
View article: Evaluating the effect of measles and rubella mass vaccination campaigns on seroprevalence in India: a before-and-after cross-sectional household serosurvey in four districts, 2018–2020
Evaluating the effect of measles and rubella mass vaccination campaigns on seroprevalence in India: a before-and-after cross-sectional household serosurvey in four districts, 2018–2020 Open
The Bill & Melinda Gates Foundation and Indian Council of Medical Research.
View article: Nursing and experimental research: A correlative perspective
Nursing and experimental research: A correlative perspective Open
Nursing as such is considered a noble profession that has possibilities for making it a research based profession. Research is an important entity that shapes and develops every profession and discipline. Historically, it is well known tha…
View article: Ameliorating effects of cinnamon and curcumin on oxidative stress in lithium-pilocarpine induced status epilepticus model
Ameliorating effects of cinnamon and curcumin on oxidative stress in lithium-pilocarpine induced status epilepticus model Open
The lithium-pilocarpine (Li-Pc) model of status epilepticus (SE) is most convenient and is frequently used for pathophysiological and management strategies in search of new, safe and effective therapeutic agents including the natural remed…
View article: Overexpression of MUC1 Induces Non-Canonical TGF-β Signaling in Pancreatic Ductal Adenocarcinoma
Overexpression of MUC1 Induces Non-Canonical TGF-β Signaling in Pancreatic Ductal Adenocarcinoma Open
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human cancers. Transforming Growth Factor Beta (TGF-β) is a cytokine that switches from a tumor-suppressor at early stages to a tumor promoter in the late stages of tumor dev…
View article: Neurobehavioral toxic effects of perinatal oral exposure to lithium on the developmental motor reflexes, cognitive dysfunction and brain oxidative stress of mice offspring
Neurobehavioral toxic effects of perinatal oral exposure to lithium on the developmental motor reflexes, cognitive dysfunction and brain oxidative stress of mice offspring Open
In the present study, the perinatal oral exposure of pregnant mice to 15 and 30mg/kg lithium (lithium chloride) in their drinking water resulted in a significant and dose-dependent reduction in postnatal body weight gain, delays in opening…
View article: Three-Dimensional Modeling of Wave Propagation over Different Types of Terrains and Environments Using the Parabolic Equation Solved by Higher Order Approximation of the Finite Difference Method
Three-Dimensional Modeling of Wave Propagation over Different Types of Terrains and Environments Using the Parabolic Equation Solved by Higher Order Approximation of the Finite Difference Method Open
Designing communications and radar systems depends on accurate modeling of ground waves in three-dimensional environment. Propagation of ground waves in the VHF and UHF bands affected by the characteristics of the terrain and the troposphe…
View article: Therapeutic value of the metabolomic active neurotransmitter isorhynchophylline in the treatment of spontaneously hypertensive rats by regulating neurotransmitters
Therapeutic value of the metabolomic active neurotransmitter isorhynchophylline in the treatment of spontaneously hypertensive rats by regulating neurotransmitters Open
Hypertension is one of the most reported cardiovascular and cerebrovascular diseases with significantly high morbidity and mortality rates. This condition threatens the very existence of human beings. Numerous studies conducted earlier rev…
View article: Construction of a Nanosensor for Non-Invasive Imaging of Hydrogen Peroxide Levels in Living Cells
Construction of a Nanosensor for Non-Invasive Imaging of Hydrogen Peroxide Levels in Living Cells Open
Hydrogen peroxide (H2O2) serves fundamental regulatory functions in metabolism beyond the role as damage signal. During stress conditions, the level of H2O2 increases in the cells and causes oxidative stress, which interferes with normal c…
View article: Characterization of Cucurbit Yellow Stunting Disorder Virus Associated with Yellowing Disease of Watermelon in Saudi Arabia
Characterization of Cucurbit Yellow Stunting Disorder Virus Associated with Yellowing Disease of Watermelon in Saudi Arabia Open
During the spring season of 2014, watermelon leaves were exhibiting yellowing, mottling and stunting symptoms in Western and Southwestern regions (Jeddah, Al-Lith, Jezan, Asfan, Ghonfada, Tofeel, Wadi Baish, Abu Arish), Saudi Arabia.One hu…