Tahmeed Ahmed
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View article: Genomic Evolution of Vibrio cholerae O1 El Tor Strains and Climatic Factors in Driving Cholera Surges in Dhaka, Bangladesh, 1996-2024
Genomic Evolution of Vibrio cholerae O1 El Tor Strains and Climatic Factors in Driving Cholera Surges in Dhaka, Bangladesh, 1996-2024 Open
Vibrio cholerae O1 El Tor strains responsible for endemic and epidemic cholera exhibit high genomic divergence in Bangladesh, although their relationship with the epidemiology and transmission of the disease has not been elucidated. Our in…
View article: Epidemiology and clinical profile of diarrhea associated with enterotoxigenic Escherichia coli and Vibrio cholerae in Bangladesh: Findings from a hospital-based surveillance system, 2008–2023
Epidemiology and clinical profile of diarrhea associated with enterotoxigenic Escherichia coli and Vibrio cholerae in Bangladesh: Findings from a hospital-based surveillance system, 2008–2023 Open
Background Enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae are notable enteric bacterial pathogens that cause diarrheal illnesses in resource-limited settings (e.g., Bangladesh). We aimed to explore the epidemiology and the cli…
View article: Impact of asymptomatic Cryptosporidium infection on nutritional status in children under two: a multi-country cohort study
Impact of asymptomatic Cryptosporidium infection on nutritional status in children under two: a multi-country cohort study Open
View article: Using gnotobiotic mice to decipher effects of gut microbiome repair in undernourished children on tuft and goblet cell function
Using gnotobiotic mice to decipher effects of gut microbiome repair in undernourished children on tuft and goblet cell function Open
Studies have implicated perturbations in the postnatal development of the gut microbiome as a contributing factor to childhood undernutrition. Compared to a standard ready-to-use supplementary food, a microbiome-directed complementary food…
View article: Association of Intestinal Alkaline Phosphatase and vitamin D level with enteric pathogens in children: results from the MAL-ED study in Bangladesh
Association of Intestinal Alkaline Phosphatase and vitamin D level with enteric pathogens in children: results from the MAL-ED study in Bangladesh Open
Objective: Intestinal Alkaline Phosphatase (IAP), expressed by enterocytes, maintains gut homeostasis by promoting commensal microbiota growth and limiting inflammation. Vitamin D strengthens intestinal barrier, and its deficiency is linke…
View article: The Effectiveness of the Structural and Functional Organization of Islamic Banking Windows in Algeria: A Critical Examination of Sharia Compliance, Operational Integration, and Financial Performance
The Effectiveness of the Structural and Functional Organization of Islamic Banking Windows in Algeria: A Critical Examination of Sharia Compliance, Operational Integration, and Financial Performance Open
View article: Region-specific variation and determinants of caesarean delivery among ever-married women in Bangladesh
Region-specific variation and determinants of caesarean delivery among ever-married women in Bangladesh Open
Background The extensive use of caesarean delivery has adverse consequences for both maternal and neonatal health. This study aims is to investigate regional variation and identify region-specific determinants of caesarean deliveries among…
View article: Fecal pH as a marker of stunting among children hospitalized for diarrhea and other non-diarrheal pathologies
Fecal pH as a marker of stunting among children hospitalized for diarrhea and other non-diarrheal pathologies Open
Background: Fecal pH is a simple, non-invasive diagnostic tool used for initial screening of certain gastrointestinal (GI) diseases. Increased fecal pH indicates reduction of beneficial microbiota in the gut, which has emerged as a key fac…
View article: Antimicrobial Usage Among Acutely Ill Hospitalized Children Aged 2‒23 Months in Sub-Saharan Africa and South Asia
Antimicrobial Usage Among Acutely Ill Hospitalized Children Aged 2‒23 Months in Sub-Saharan Africa and South Asia Open
Background Understanding patterns of antimicrobial use is critical to supporting antibiotic stewardship and limiting antimicrobial resistance (AMR). We aimed to describe antimicrobial prescribing in acutely ill hospitalized children aged 2…
View article: Qualitative approach to assess maternal knowledge, attitude and practice regarding oral rehydration solution preparation and administration among under-5 children suffering from diarrhoea in Dhaka, Bangladesh
Qualitative approach to assess maternal knowledge, attitude and practice regarding oral rehydration solution preparation and administration among under-5 children suffering from diarrhoea in Dhaka, Bangladesh Open
Background Oral rehydration salt (ORS) solution has been instrumental in substantially reducing diarrhoea-related mortality, particularly in resource-constrained settings such as Bangladesh. However, the full effectiveness of ORS is often …
View article: Neuraminidase-3 activity in toddlers negatively impacts the linear growth status in Bangladeshi children
Neuraminidase-3 activity in toddlers negatively impacts the linear growth status in Bangladeshi children Open
Linear growth faltering and stunting in children is associated with inflammation of small gut. Intestinal alkaline phosphatase prevents gut inflammation from subclinical bacterial infection that becomes impaired in the presence of neuramin…
View article: Key Stakeholders' Perspectives on Acute Malnutrition Management Programs for Children Under Five in Bangladesh: Qualitative Insights
Key Stakeholders' Perspectives on Acute Malnutrition Management Programs for Children Under Five in Bangladesh: Qualitative Insights Open
Acute malnutrition (AM) in children under five is a significant global health concern. Community‐based management of AM (CMAM) with provision of specially formulated foods (SFFs) is recommended for treating moderate (MAM) and uncomplicated…
View article: Impact of Asymptomatic Enteroaggregative <i>Escherichia coli</i> Infection and Co-Pathogen Burden on Intestinal Barrier Function, Linear Growth, and Cognitive Development in Early Childhood: Insights from a Birth Cohort Study
Impact of Asymptomatic Enteroaggregative <i>Escherichia coli</i> Infection and Co-Pathogen Burden on Intestinal Barrier Function, Linear Growth, and Cognitive Development in Early Childhood: Insights from a Birth Cohort Study Open
Introduction Enteroaggregative Escherichia coli (EAEC) is a major enteric pathogen in low-resource settings and can infect children with or without causing diarrhea. However, limited data exists on the impact of subclinical EAEC infections…
View article: Cost of diarrhoea: a household perspective from seven countries in the Global Enteric Multicentre Study (GEMS)
Cost of diarrhoea: a household perspective from seven countries in the Global Enteric Multicentre Study (GEMS) Open
Background The burden of diarrhoeal diseases is considerable in South Asia, as well as in sub-Saharan Africa. Its economic impact is more profound in resource-limited settings like low-income and middle-income countries (LMICs). In this st…
View article: Is rotavirus aetiology in young children with acute diarrhoea associated with sociodemographic and clinical factors, including rotavirus vaccination status? A secondary cross-sectional analysis of the ABCD trial
Is rotavirus aetiology in young children with acute diarrhoea associated with sociodemographic and clinical factors, including rotavirus vaccination status? A secondary cross-sectional analysis of the ABCD trial Open
Introduction One of the leading causes of global child mortality continues to be diarrhoea where rotavirus contributed to about 24% of deaths among all diarrhoeal deaths, mostly in low-income and middle-income countries. Rotavirus vaccinat…
View article: Aflatoxin exposure and mortality in acutely ill children: results from the CHAIN network cohort
Aflatoxin exposure and mortality in acutely ill children: results from the CHAIN network cohort Open
Background Chronic exposure to aflatoxins is associated with liver cancer, impaired child growth, and compromised immune function. The Childhood Acute Illness and Nutrition (CHAIN) Network cohort was established to identify risk factors fo…
View article: Severe infection incidence among young infants in Dhaka, Bangladesh: an observational cohort study
Severe infection incidence among young infants in Dhaka, Bangladesh: an observational cohort study Open
Introduction Heterogeneity in definitions of severe infection, sepsis and serious bacterial infection (SBI) in infants limits the comparability of randomised controlled trials (RCTs) of infection prevention interventions. To inform the des…
View article: Determinants of post-discharge stunting among diarrhoeal children aged 2–23 months in Bangladesh: findings from Antibiotics for Children with Severe Diarrhea (ABCD) trial
Determinants of post-discharge stunting among diarrhoeal children aged 2–23 months in Bangladesh: findings from Antibiotics for Children with Severe Diarrhea (ABCD) trial Open
Our study highlights the need for targeted interventions to mitigate persistent stunting in this vulnerable group recovering from diarrhoea.
View article: Growth monitoring and promotion program services utilization patterns between home-based and facility-based delivery methods: A comparative analysis
Growth monitoring and promotion program services utilization patterns between home-based and facility-based delivery methods: A comparative analysis Open
Background In Bangladesh, utilization of government health facility-based growth monitoring and promotion (GMP) services is notably low, prompting non-governmental organizations (NGOs) to collaborate with the government to enhance GMP serv…
View article: Maternal perception, barriers, and facilitators regarding oral rehydration salt solution in diarrhoeal disease: A qualitative study in Bangladesh
Maternal perception, barriers, and facilitators regarding oral rehydration salt solution in diarrhoeal disease: A qualitative study in Bangladesh Open
Background Although oral rehydration salt (ORS) solution is a lifesaving management for diarrhoea, its exertion is still surprisingly low among caregivers. As mothers are considered to be the primary caregivers, they bear the responsibilit…
View article: Ancestral trajectory of infant gut microbiome assembly in non-industrialised populations
Ancestral trajectory of infant gut microbiome assembly in non-industrialised populations Open
Infant gut microbiome assembly influences childhood growth and development. However, current understanding is based almost exclusively on infants from highly industrialised, high-income countries. Here, we present a high-resolution map of …
View article: Gender Equity Issues in Orthopaedics: A Scoping Review
Gender Equity Issues in Orthopaedics: A Scoping Review Open
View article: Elevated aspartate aminotransferase (AST) as a predictive biomarker for diagnosing enteric fever in out-patient departments
Elevated aspartate aminotransferase (AST) as a predictive biomarker for diagnosing enteric fever in out-patient departments Open
View article: Dysmagnesemia in critically ill diarrheal patients in Bangladesh
Dysmagnesemia in critically ill diarrheal patients in Bangladesh Open
Background Despite having a pivotal role in numerous physiologic functions, magnesium disorders are rarely considered in clinical practice. This study aimed to explore the burden, predictors, and outcomes associated with magnesium imbalanc…
View article: Small intestinal microbiota of undernourished women of reproductive age and microbiota-directed balanced energy protein (MD-BEP) supplementation in maternal environmental enteric dysfunction (EED): protocol for a community-based intervention study
Small intestinal microbiota of undernourished women of reproductive age and microbiota-directed balanced energy protein (MD-BEP) supplementation in maternal environmental enteric dysfunction (EED): protocol for a community-based intervention study Open
Introduction Studies show, malnourished women of childbearing age with environmental enteric dysfunction (EED) exhibit small intestinal enteropathy resembling that in malnourished children residing in the same community. However, currently…
View article: Clinico-Epidemiological Characteristics of Symptomatic and Asymptomatic Enterotoxigenic and Enteropathogenic Escherichia Coli Diarrhea and Impact on Child Growth
Clinico-Epidemiological Characteristics of Symptomatic and Asymptomatic Enterotoxigenic and Enteropathogenic Escherichia Coli Diarrhea and Impact on Child Growth Open
Enterotoxigenic Escherichia ( E. ) coli (ETEC) and enteropathogenic E. coli (EPEC) are major bacterial causes of childhood diarrhea. We explored the clinico-epidemiological characteristics of children aged <5 years associated with moderate…
View article: Societal cost of day-care approach (DCA): A low-cost approach in urban and rural settings for management of childhood severe pneumonia in Bangladesh
Societal cost of day-care approach (DCA): A low-cost approach in urban and rural settings for management of childhood severe pneumonia in Bangladesh Open
Objective Childhood severe pneumonia is the leading cause of under-five deaths in Bangladesh. A new day-care management approach (DCA) was implemented in primary-level healthcare facilities in urban and rural areas of Bangladesh. Reliable …
View article: Association of Escherichia coli pathotypes with fecal markers of enteropathy and nutritional status among underweight adults in Bangladesh
Association of Escherichia coli pathotypes with fecal markers of enteropathy and nutritional status among underweight adults in Bangladesh Open
Introduction Environmental enteric dysfunction (EED), a subclinical intestinal disorder, is characterized by chronic fecal-oral exposure to entero-pathogens and could be diagnosed by measuring non-invasive biomarkers. Escherichia coli is t…
View article: Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis
Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis Open
BACKGROUND: Selenium (Se), an essential trace mineral, has been implicated in preterm birth (PTB). We aimed to determine the association of maternal Se concentrations during pregnancy with PTB risk and gestational duration in a large numbe…
View article: Perceptions of Underlying Factors and Consequences of Childhood Malnutrition and Care‐Seeking Behaviour for Children Under 5 Years With Acute Malnutrition: A Qualitative Study in Rural Bangladesh
Perceptions of Underlying Factors and Consequences of Childhood Malnutrition and Care‐Seeking Behaviour for Children Under 5 Years With Acute Malnutrition: A Qualitative Study in Rural Bangladesh Open
Acute Malnutrition affects 45 million children under five globally, with Bangladesh contributing more than 1.7 million cases. While community‐based management of acute malnutrition (CMAM) guidelines in Bangladesh exist, they primarily emph…