Explanipedia

Comparative pathogenic potential of avian influenza H7N3 viruses isolated from wild birds in Egypt and their sensitivity to commercial antiviral drugs Open

Ahmed E. Kayed, Omnia Kutkat, Ahmed Kandeil, Yassmin Moatasim, Ahmed El Taweel , et al. · 2023

Active surveillance and genetic evolution of avian influenza viruses in Egypt, 2016–2018 Open

Ahmed Kandeil, Joseph T. Hicks, Sean G. Young, Ahmed N. El Taweel, Ahmed E. Kayed , et al. · 2023

Egypt is a hotspot for avian influenza virus (AIV) due to the endemicity of H5N1 and H9N2 viruses. AIVs were isolated from 329 samples collected in 2016–2018; 48% were H9N2, 37.1% were H5N8, 7.6% were H5N1, and 7.3% were co-infections with…

Cross-Sectional Study and Descriptive Statistical Analysis During a Period of Time of One Year Extending From the Beginning of January to the End of December 2020 of Alleged Child Sexual Abuse Cases in Cairo Governorate in Egypt Open

Mahmoud Mohamed, Magdy Ismail, Mohamed Asasa, Ahmed E. Kayed · 2022

Background: Child sexual abuse is a common offensive aspect of children's rights worldwide.Immature Childs are liable for more abuse as they are not able to produce any defend action against the assailant due to immature cognitive and body…

Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2 Open

Ahmed Kandeil, Ahmed Mostafa, Omnia Kutkat, Yassmin Moatasim, Ahmed A. Al‐Karmalawy , et al. · 2021

Until now, there has been no direct evidence of the effectiveness of repurposed FDA-approved drugs against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections. Although curcumin, hesperidin, and quercetin have broad spe…

Molecular Characterization of Closely Related H6N2 Avian Influenza Viruses Isolated from Turkey, Egypt, and Uganda Open

Yavuz Mercan, Gladys Atim, Ahmed E. Kayed, M. Ekin Azbazdar, Ahmed Kandeil , et al. · 2021

Genetic analysis of circulating avian influenza viruses (AIVs) in wild birds at different geographical regions during the same period could improve our knowledge about virus transmission dynamics in natural hosts, virus evolution as well a…

Incidence, household transmission, and neutralizing antibody seroprevalence of Coronavirus Disease 2019 in Egypt: Results of a community-based cohort Open

Mokhtar R. Gomaa, Amira S. El Refay, Mahmoud Shehata, Ahmed Kandeil, Mina Nabil Kamel , et al. · 2021

SARS-CoV-2 virus is transmitted in closed settings to people in contact with COVID-19 patients such as healthcare workers and household contacts. However, household person-to-person transmission studies are limited. Households participatin…

Immunogenicity and Safety of an Inactivated SARS-CoV-2 Vaccine: Preclinical Studies Open

Ahmed Kandeil, Ahmed Mostafa, Rehab Hegazy, Rabeh El‐Shesheny, Ahmed El Taweel , et al. · 2021

Since the emergence of SARS-CoV-2 at the end of 2019, 64 candidate vaccines are in clinical development and 173 are in the pre-clinical phase. Five types of vaccines are currently approved for emergency use in many countries (Inactivated, …

Active surveillance and genetic evolution of avian influenza viruses in Egypt, 2016–2018 Open

Ahmed Kandeil, Joseph T. Hicks, Sean G. Young, Ahmed N. El Taweel, Ahmed E. Kayed , et al. · 2021

Egypt is a hotspot for avian influenza virus (AIV) due to the endemicity of H5N1 and H9N2 viruses. AIVs were isolated from 329 samples collected in 2016–2018; 48% were H9N2, 37.1% were H5N8, 7.6% were H5N1, and 7.3% were co-infections with…

FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2 Open

Ahmed Mostafa, Ahmed Kandeil, Yaseen A.M.M. Elshaier, Omnia Kutkat, Yassmin Moatasim , et al. · 2020

(1) Background: Drug repositioning is an unconventional drug discovery approach to explore new therapeutic benefits of existing drugs. Currently, it emerges as a rapid avenue to alleviate the COVID-19 pandemic disease. (2) Methods: Herein,…

Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Antibodies in Egyptian Convalescent Plasma Donors Open

Mokhtar R. Gomaa, Ahmed Kandeil, Ahmed Mostafa, Wael H. Roshdy, Ahmed E. Kayed , et al. · 2020

Using convalescent plasma as immunotherapy is an old method for treatment of infectious diseases. Several countries have recently allowed the use of such therapy for the treatment of COVID-19 patients especially those who are critically il…

Common childhood vaccines do not elicit a cross-reactive antibody response against SARS-CoV-2 Open

Ahmed Kandeil, Mokhtar R. Gomaa, Ahmed El Taweel, Ahmed Mostafa, Mahmoud Shehata , et al. · 2020

Anecdotal evidence showed a negative correlation between Bacille Calmette-Guérin (BCG) vaccination and incidence of COVID-19. Incidence of the disease in children is much lower than in adults. It is hypothesized that BCG and other childhoo…

Coding-Complete Genome Sequences of Two SARS-CoV-2 Isolates from Egypt Open

Ahmed Kandeil, Ahmed Mostafa, Rabeh El‐Shesheny, Mahmoud Shehata, Wael H. Roshdy , et al. · 2020

This report announces the complete genome sequences of two severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolates detected in Egypt. The isolates were obtained from oropharyngeal swab specimens from two Egyptians in Upper an…

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East Open

Ahmed Kandeil, Mokhtar R. Gomaa, Ahmed Nageh, Mahmoud Shehata, Ahmed E. Kayed , et al. · 2019

Dromedary camels are the natural reservoirs of the Middle East respiratory syndrome coronavirus (MERS-CoV). Camels are mostly bred in East African countries then exported into Africa and Middle East for consumption. To understand the distr…

Development of an effective contemporary trivalent avian influenza vaccine against circulating H5N1, H5N8, and H9N2 in Egypt Open

Mokhtar R. Gomaa, Ahmed Khalil, Ahmed Kandeil, Jamal S. M. Sabir, Ahmed E. Kayed , et al. · 2019

Low pathogenicity avian influenza (LPAI) H9N2, highly pathogenic avian influenza (HPAI) H5N1, and H5N8 circulate in Egyptian poultry and cause veterinary and public health burdens. In response, AIV vaccines are commonly used. The main obje…

Effect of Using Yeast (Saccharomyces Cerevisiae) and Mushroom (Pleurotus Ostreatus) as Natural Feed Additives on Productive and Immune Response of Broiler Chicks Open

A. Abou-Zeid, S. El-Damarawy, Y. Mariey, Ahmed E. Kayed · 2019

An experiment was conducted to study the effect of yeast (saccharomyces cerevisiae) and mushroom (pleurotus ostreatus) as natural feed additives on the productive and immune response of broilers. 375 Cobb broiler chicks, aged one day-old w…

Surveillance for avian influenza viruses in wild birds at live bird markets, Egypt, 2014‐2016 Open

Ahmed E. Kayed, Ahmed Kandeil, Mokhtar R. Gomaa, Rabeh El‐Shesheny, Sara H. Mahmoud , et al. · 2019

Aim Egypt is the habitat for a large number of bird species and serves as a vital stopover for millions of migratory birds during their annual migration between the Palearctic and Afrotropical ecozones. Surveillance for avian influenza vir…

Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals Open

Ahmed Kandeil, Mokhtar R. Gomaa, Mahmoud Shehata, Ahmed Nageh El-Taweel, Ahmed E. Kayed , et al. · 2019

Dromedary camels are natural host of the Middle East respiratory syndrome coronavirus (MERS-CoV). However, there are limited studies of MERS-CoV infection of other domestic mammals exposed to infected dromedaries. We expanded our surveilla…

Active surveillance and genetic evolution of avian influenza viruses in Egypt, 2016–2018 Open

Ahmed Kandeil, Joseph T. Hicks, Sean G. Young, Ahmed N. El Taweel, Ahmed E. Kayed , et al. · 2019

Egypt is a hotspot for avian influenza virus (AIV) due to the endemicity of H5N1 and H9N2 viruses. AIVs were isolated from 329 samples collected in 2016-2018; 48% were H9N2, 37.1% were H5N8, 7.6% were H5N1, and 7.3% were co-infections with…

Active surveillance and genetic evolution of avian influenza viruses in Egypt, 2016–2018 Open

Ahmed Kandeil, Joseph T. Hicks, Sean G. Young, Ahmed N. El Taweel, Ahmed E. Kayed , et al. · 2019

Egypt is a hotspot for avian influenza virus (AIV) due to the endemicity of H5N1 and H9N2 viruses. AIVs were isolated from 329 samples collected in 2016–2018; 48% were H9N2, 37.1% were H5N8, 7.6% were H5N1, and 7.3% were co-infections with…

Isolation and Characterization of a Distinct Influenza A Virus from Egyptian Bats Open

Ahmed Kandeil, Mokhtar R. Gomaa, Mahmoud Shehata, Ahmed N. El Taweel, Sara H. Mahmoud , et al. · 2018

Through surveillance, we isolated and characterized an influenza A virus from Egyptian fruit bats. This virus had an affinity to avian-like receptors but was also able to infect mice. Our findings indicate that bats may harbor a diversity …

Genetic characterization of highly pathogenic avian influenza A H5N8 viruses isolated from wild birds in Egypt Open

Ahmed Kandeil, Ahmed E. Kayed, Yassmin Moatasim, Richard J. Webby, Pamela McKenzie , et al. · 2017

A newly emerged H5N8 influenza virus was isolated from green-winged teal in Egypt during December 2016. In this study, we provide a detailed characterization of full genomes of Egyptian H5N8 viruses and some virological features. Genetic a…

Systematic, active surveillance for Middle East respiratory syndrome coronavirus in camels in Egypt Open

Mohamed A. Ali, Mahmoud Shehata, Mokhtar R. Gomaa, Ahmed Kandeil, Rabeh El‐Shesheny , et al. · 2017

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe human infections and dromedary camels are considered an intermediary host. The dynamics of natural infection in camels are not well understood. Through systematic survei…

Active surveillance of avian influenza viruses in Egyptian poultry, 2015 Open

Ahmed E. Kayed, Ahmed Kandeil, Rabeh El‐Shesheny, Mohamed A. Ali, Ghazi Kayali · 2016

Surveillance for avian influenza viruses in Egyptian poultry has been conducted since 2009. Up to 2011, all the detected viruses were H5N1, and the overall prevalence was 5%. In 2011, H9N2 viruses were observed to be co-circulating and co-…

Serological Evidence of Human Infection with Avian Influenza A H7virus in Egyptian Poultry Growers Open

Mokhtar R. Gomaa, Ahmed Kandeil, Ahmed E. Kayed, Mona A. Elabd, Shaimaa A. Zaki , et al. · 2016

Avian influenza viruses circulate widely in birds, with occasional human infections. Poultry-exposed individuals are considered to be at high risk of infection with avian influenza viruses due to frequent exposure to poultry. Some avian H7…

Avian Influenza A(H5N1) Virus in Egypt Open

Ghazi Kayali, Ahmed Kandeil, Rabeh El‐Shesheny, Ahmed E. Kayed, Asmaa M. Maatouq , et al. · 2016

In Egypt, avian influenza A subtype H5N1 and H9N2 viruses are enzootic in poultry. The control plan devised by veterinary authorities in Egypt to prevent infections in poultry focused mainly on vaccination and ultimately failed. Recently, …

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