Ahmed M. E. Elrefaey
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View article: Nipah virus vaccines evaluated in pigs as a ‘One Health’ approach to protect public health
Nipah virus vaccines evaluated in pigs as a ‘One Health’ approach to protect public health Open
Nipah virus (NiV) causes a severe neurological disease in humans. The first NiV outbreak, in Malaysia, involved pig-to-human transmission, that resulted in significant economic losses to the local pig industry. Despite the risk NiV poses t…
View article: Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2
Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2 Open
SARS-CoV-2 variants may threaten the effectiveness of vaccines and antivirals to mitigate serious COVID-19 disease. This is of most concern in clinically vulnerable groups such as older adults. We analysed 72 sera samples from 37 individua…
View article: Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients
Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients Open
View article: Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway
Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway Open
View article: Innate Immune Antagonism of Mosquito-Borne Flaviviruses in Humans and Mosquitoes
Innate Immune Antagonism of Mosquito-Borne Flaviviruses in Humans and Mosquitoes Open
Mosquito-borne viruses of the Flavivirus genus (Flaviviridae family) pose an ongoing threat to global public health. For example, dengue, Japanese encephalitis, West Nile, yellow fever, and Zika viruses are transmitted by infected mosquito…
View article: Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway.
Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway. Open
SARS-CoV-2 has a broad mammalian species tropism infecting humans, cats, dogs and farmed mink. Since the start of the 2019 pandemic several reverse zoonotic outbreaks of SARS-CoV-2 have occurred in mink, one of which reinfected humans and …
View article: Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway
Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway Open
SARS-CoV-2 has a broad mammalian species tropism infecting humans, cats, dogs and farmed mink. Since the start of the 2019 pandemic several reverse zoonotic outbreaks of SARS-CoV-2 have occurred in mink, one of which reinfected humans and …
View article: Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected Patients
Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected Patients Open
RaTG13 is a close relative of SARS-CoV-2, the virus responsible for the Coronavirus Disease 2019 (COVID-19) pandemic, sharing 96% sequence similarity at the genome-wide level. The spike receptor binding domain (RBD) of RaTG13 contains a la…
View article: Understanding the Mechanisms Underlying Host Restriction of Insect-Specific Viruses
Understanding the Mechanisms Underlying Host Restriction of Insect-Specific Viruses Open
Arthropod-borne viruses contribute significantly to global mortality and morbidity in humans and animals. These viruses are mainly transmitted between susceptible vertebrate hosts by hematophagous arthropod vectors, especially mosquitoes. …