Ahmet Gökhan Ağgül
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View article: Protective Effects of Lemon Leaf and Limonene against Indomethacin-Induced Gastric Ulcers in Rats: An In Vivo and In Silico Study
Protective Effects of Lemon Leaf and Limonene against Indomethacin-Induced Gastric Ulcers in Rats: An In Vivo and In Silico Study Open
This paper aims to assess the possible protective effects of the lemon leaves and its main component, limonene, which is known for its active principles and health benefits, against indomethacin-induced oxidative stress in the rats. In thi…
View article: Biochemical and Histopathological Evaluation of The Effect of Thiamine Pyrophosphate on Favipiravir-İnduced Degenerative Corneal and Scleral Damage in Rats
Biochemical and Histopathological Evaluation of The Effect of Thiamine Pyrophosphate on Favipiravir-İnduced Degenerative Corneal and Scleral Damage in Rats Open
Abstract Introduction: Favipiravir causes ocular toxicity at high doses. Thiamine pyrophosphate (TPP) therapy can prevent ocular damage by reversing oxidative damage. Objective: To investigate the ocular effect of favipiravir in rats and d…
View article: Effect of Taxifolin on Acrylamide-Related Oxidative Ovarian Damage, Infertility and Intrauterine Growth Retardation in Female Rats
Effect of Taxifolin on Acrylamide-Related Oxidative Ovarian Damage, Infertility and Intrauterine Growth Retardation in Female Rats Open
Background and Objective: Acrylamide (AA) is a toxin that can cause reproductive organ toxicity and infertility through oxidative stress.This study aimed to investigate the effect of taxifolin, an antioxidant flavonoid, against acrylamide-…
View article: Molecular mechanism of the protective effect of adenosine triphosphate against paracetamol-induced liver toxicity in rats
Molecular mechanism of the protective effect of adenosine triphosphate against paracetamol-induced liver toxicity in rats Open
Toxic doses of paracetamol are also known to be close to therapeutic doses. This study aimed to biochemically investigate the protective effect of ATP against paracetamol-induced oxidative liver injury in rats and to examine the tissues hi…
View article: Ether Extract of Olive (Olea europaea L.) Leaf: Potential Effect on Streptozotocin-Induced Oxidative Stress in Rats
Ether Extract of Olive (Olea europaea L.) Leaf: Potential Effect on Streptozotocin-Induced Oxidative Stress in Rats Open
The study’s aim is to investigate the protective effects of olive (Olea europaea L.) leaf ether extract, due to its rich phenolic content and beneficial health effects, on streptozotocin (STZ)-induced oxidative stress in rats. Diabetes in …
View article: Oleuropein and Verbascoside - Their Inhibition Effects on Carbonic Anhydrase and Molecular Docking Studies
Oleuropein and Verbascoside - Their Inhibition Effects on Carbonic Anhydrase and Molecular Docking Studies Open
Recently, carbonic anhydrase (CA, E.C.4.2.1.1) inhibitors from natural product have paved the way for novel drug design in the treatment and prevention of some global diseases such as glaucoma, diabetes, and cancer. For this purpose, the i…
View article: Effects of Emulsion Formulations of Oleuropein Isolated from Ethanol Extract of Olive Leaf in Diabetic Rats
Effects of Emulsion Formulations of Oleuropein Isolated from Ethanol Extract of Olive Leaf in Diabetic Rats Open
This study was designed to investigate the effects of emulsion formulations of oleuropein isolated from ethanol extract of olive leaf in streptozotocin-diabetic rats. The rats were treated with the administration of the emulsion containing…
View article: Alterations in Enzyme Activity of Carbonic Anhydrase, 6-phosphogluconate Dehydrogenase and Thioredoxin Reductase in Rats Exposed to Doxorubicin and Morin
Alterations in Enzyme Activity of Carbonic Anhydrase, 6-phosphogluconate Dehydrogenase and Thioredoxin Reductase in Rats Exposed to Doxorubicin and Morin Open
Objective:Carbonic anhydrase (CA), 6-phosphogluconate dehydrogenase (6PGD) andthioredoxin reductase (TrxR) enzymes are the essential biological molecules needed for metabolic processes in all livingcells. This study was designed to investi…
View article: Effects of Emulsion Formulations of Oleuropein Isolated from Ethanol Extract of Olive Leaf in Diabetic Rats
Effects of Emulsion Formulations of Oleuropein Isolated from Ethanol Extract of Olive Leaf in Diabetic Rats Open
This study was designed to investigate the effects of emulsion formulations of oleuropein isolated from ethanol extract of olive leaf in streptozotocin-diabetic rats. The rats were treated with the administration of the emulsion containing…
View article: Antioxidant and Antidiabetic Activity of Aqueous Extract of Myrtus Communis L. Berries on Streptozotocin-Induced Diabetic Rats
Antioxidant and Antidiabetic Activity of Aqueous Extract of Myrtus Communis L. Berries on Streptozotocin-Induced Diabetic Rats Open
Background: Myrtus communis L. (MC) is widely used as an antidiabetic plant in folk medicine.This study aimed to analyze the possible antidiabetic and hepatoprotective effects of MC berries in streptozotocin (STZ)induced diabetic rats. Met…