Ahrum Baek
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View article: Physicochemical and Multimodal Imaging Properties of Core–Shell Ln2O3@Carbon Nanoparticles (Ln = Tb and Ho)
Physicochemical and Multimodal Imaging Properties of Core–Shell Ln2O3@Carbon Nanoparticles (Ln = Tb and Ho) Open
In this study, core–shell Ln2O3@carbon nanoparticles (core = Ln2O3 and shell = carbon; Ln = Tb and Ho) were synthesized for the first time by preparing Ln2O3 nanoparticles through a polyol method, followed by carbon coating using D-glucose…
View article: Current Status and Future Aspects of Gadolinium Oxide Nanoparticles as Positive Magnetic Resonance Imaging Contrast Agents
Current Status and Future Aspects of Gadolinium Oxide Nanoparticles as Positive Magnetic Resonance Imaging Contrast Agents Open
Although numerous studies have investigated gadolinium oxide (Gd2O3) nanoparticles (NPs) as positive (T1) magnetic resonance imaging (MRI) contrast agents (CAs), comprehensive reviews on this topic remain scarce. Therefore, it is essential…
View article: Magnetic Resonance Imaging and X-Ray Imaging Properties of Ultrasmall Lanthanide Oxide (Ln = Eu, Gd, and Tb) Nanoparticles Synthesized via Thermal Decomposition
Magnetic Resonance Imaging and X-Ray Imaging Properties of Ultrasmall Lanthanide Oxide (Ln = Eu, Gd, and Tb) Nanoparticles Synthesized via Thermal Decomposition Open
Owing to their 4f electrons and high atomic numbers, lanthanide (Ln) elements impart lanthanide oxide (Ln2O3) nanoparticles with excellent biomedical imaging properties. This study reports synthesis for three types of ultrasmall and monodi…
View article: Surface Modification, Toxicity, and Applications of Carbon Dots to Cancer Theranosis: A Review
Surface Modification, Toxicity, and Applications of Carbon Dots to Cancer Theranosis: A Review Open
Cancer remains one of the leading causes of death worldwide, prompting extensive research into novel theranostic (combined word of diagnostic and therapeutic) strategies. Nanomedicine has emerged as a potential breakthrough in cancer thera…
View article: Synthesis, Characterization, Magnetic Properties, and Applications of Carbon Dots as Diamagnetic Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agents: A Review
Synthesis, Characterization, Magnetic Properties, and Applications of Carbon Dots as Diamagnetic Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agents: A Review Open
Carbon dots (CDs) are metal-free carbon-based nanoparticles. They possess excellent photoluminescent properties, various physical properties, good chemical stability, high water solubility, high biocompatibility, and tunable surface functi…
View article: Synthesis, Characterization, Magnetic Properties, and Applications of Carbon Dots as Diamagnetic Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agents: A Review
Synthesis, Characterization, Magnetic Properties, and Applications of Carbon Dots as Diamagnetic Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agents: A Review Open
Carbon dots (CDs) are metal-free carbon-based nanoparticles. They possess excellent photoluminescent properties, various physical properties, good chemical stability, high water solubility, high biocompatibility, and tunable surface functi…
View article: High Quantum Yields and Biomedical Fluorescent Imaging Applications of Photosensitized Trivalent Lanthanide Ion-Based Nanoparticles
High Quantum Yields and Biomedical Fluorescent Imaging Applications of Photosensitized Trivalent Lanthanide Ion-Based Nanoparticles Open
In recent years, significant advances in enhancing the quantum yield (QY) of trivalent lanthanide (Ln3+) ion-based nanoparticles have been achieved through photosensitization, using host matrices or capping organic ligands as photosensitiz…
View article: Gadolinium-Based Magnetic Resonance Theranostic Agent with Gallic Acid as an Anti-Neuroinflammatory and Antioxidant Agent
Gadolinium-Based Magnetic Resonance Theranostic Agent with Gallic Acid as an Anti-Neuroinflammatory and Antioxidant Agent Open
Studies in the field have actively pursued the incorporation of diverse biological functionalities into gadolinium-based contrast agents, aiming at the amalgamation of MRI imaging and therapeutic capabilities. In this research, we present …
View article: Ultrasmall cerium oxide nanoparticles as highly sensitive X-ray contrast agents and their antioxidant effect
Ultrasmall cerium oxide nanoparticles as highly sensitive X-ray contrast agents and their antioxidant effect Open
Ultrasmall CeO 2 nanoparticles as highly sensitive radioprotective or theranostic X-ray contrast agents.
View article: Manganese (II) Complex of 1,4,7-Triazacyclononane-1,4,7-Triacetic Acid (NOTA) as a Hepatobiliary MRI Contrast Agent
Manganese (II) Complex of 1,4,7-Triazacyclononane-1,4,7-Triacetic Acid (NOTA) as a Hepatobiliary MRI Contrast Agent Open
Magnetic resonance imaging (MRI) is increasingly used to diagnose focal and diffuse liver disorders. Despite their enhanced efficacy, liver-targeted gadolinium-based contrast agents (GBCAs) raise safety concerns owing to the release of tox…
View article: Nonsteroidal Anti-Inflammatory Drug Conjugated with Gadolinium (III) Complex as an Anti-Inflammatory MRI Agent
Nonsteroidal Anti-Inflammatory Drug Conjugated with Gadolinium (III) Complex as an Anti-Inflammatory MRI Agent Open
Studies have been actively conducted to ensure that gadolinium-based contrast agents for magnetic resonance imaging (MRI) are accompanied by various biological functions. A new example is the anti-inflammatory theragnostic MRI agent to tar…
View article: Flavonoid-Conjugated Gadolinium Complexes as Anti-Inflammatory Theranostic Agents
Flavonoid-Conjugated Gadolinium Complexes as Anti-Inflammatory Theranostic Agents Open
In this study, we designed, synthesized, and evaluated gadolinium compounds conjugated with flavonoids as potential theranostic agents for the treatment of inflammation. These novel theranostic agents combine a molecular imaging agent and …
View article: The Synthesis, Characterization, Molecular Docking and In Vitro Antitumor Activity of Benzothiazole Aniline (BTA) Conjugated Metal-Salen Complexes as Non-Platinum Chemotherapeutic Agents
The Synthesis, Characterization, Molecular Docking and In Vitro Antitumor Activity of Benzothiazole Aniline (BTA) Conjugated Metal-Salen Complexes as Non-Platinum Chemotherapeutic Agents Open
Here, we describe the synthesis, characterization, and in vitro biological evaluation of a series of transition metal complexes containing benzothiazole aniline (BTA). We employed BTA, which is known for its selective anticancer activity, …
View article: Glioblastoma-Derived Exosomes as Nanopharmaceutics for Improved Glioma Treatment
Glioblastoma-Derived Exosomes as Nanopharmaceutics for Improved Glioma Treatment Open
The use of cancer-derived exosomes has been studied in several cancer types, but the cancer-targeting efficacy of glioma-derived exosomes has not been investigated in depth for malignant glioblastoma (GBM) cells. In this study, exosomes we…
View article: Paramagnetic ultrasmall Ho<sub>2</sub>O<sub>3</sub> and Tm<sub>2</sub>O<sub>3</sub> nanoparticles: characterization of <i>r</i><sub>2</sub> values and <i>in vivo T</i><sub>2</sub> MR images at a 3.0 T MR field
Paramagnetic ultrasmall Ho<sub>2</sub>O<sub>3</sub> and Tm<sub>2</sub>O<sub>3</sub> nanoparticles: characterization of <i>r</i><sub>2</sub> values and <i>in vivo T</i><sub>2</sub> MR images at a 3.0 T MR field Open
Paramagnetic ultrasmall Ho 2 O 3 and Tm 2 O 3 nanoparticles grafted with various hydrophilic and biocompatible ligands as a new class of efficient T 2 MRI contrast agents were investigated in this study.
View article: Synthesis, Characterization, and Anticancer Activity of Benzothiazole Aniline Derivatives and Their Platinum (II) Complexes as New Chemotherapy Agents
Synthesis, Characterization, and Anticancer Activity of Benzothiazole Aniline Derivatives and Their Platinum (II) Complexes as New Chemotherapy Agents Open
We describe the synthesis, characterization, molecular modeling, and in vitro anticancer activity of three benzothiazole aniline (BTA) ligands and their corresponding platinum (II) complexes. We designed the compounds based on the selectiv…