Explanipedia

LB1071 Differentiation and proteomic insights into psoriasis and TNFi-induced psoriatic dermatitis in pediatric patients Open

Bryan A. Liang, Mariana McCune, Ah‐Young Kwon, Steven Phan, Eric H. Yang , et al. · 2025

Author Correction: Systematic dissection of tumor-normal single-cell ecosystems across a thousand tumors of 30 cancer types Open

Junho Kang, Jun Hyeong Lee, Hongui Cha, Jinhyeon An, Joonha Kwon , et al. · 2025

Comparative analysis of clinical image evaluation charts for panoramic radiography Open

Yeon Hee Kim, Sam-Sun Lee, Gyu-Dong Jo, Ah‐Young Kwon, Ju‐Hee Kang , et al. · 2024

Objective To compare and analyze professional (P chart) and simple (S chart) clinical image evaluation charts for evaluating panoramic radiograph image quality. Methods Ten evaluators assessed 285 clinical panoramic radiograph images. The …

Systematic dissection of tumor-normal single-cell ecosystems across a thousand tumors of 30 cancer types Open

Junho Kang, Jun Hyeong Lee, Hongui Cha, Jinhyeon An, Joonha Kwon , et al. · 2024

The complexity of the tumor microenvironment poses significant challenges in cancer therapy. Here, to comprehensively investigate the tumor-normal ecosystems, we perform an integrative analysis of 4.9 million single-cell transcriptomes fro…

Lipoma with osteocartilaginous metaplasia in infrapatellar fat pad: A case report and review of literature Open

Segi Kim, Cheungsoo Ha, Ah‐Young Kwon, Wonchul Choi · 2022

Rationale: Lipomas are tumors composed of mature adipocytes, originating from the mesoderm, and are the most common soft tissue tumor. According to the World Health Organization classification of human soft tissue and bone tumors, there ar…

miR-22-3p and miR-30e-5p Are Associated with Prognosis in Cervical Squamous Cell Carcinoma Open

Ah‐Young Kwon, Ju‐Yeon Jeong, Hyun Park, Sohyun Hwang, Gwangil Kim , et al. · 2022

Alteration in expression of miRNAs can cause various malignant changes and the metastatic process. Our aim was to identify the miRNAs involved in cervical squamous cell carcinoma (SqCC) and metastasis, and to test their utility as indicato…

Predictive biomarkers for the responsiveness to autologous activated killer cell immunotherapy in recurrent Glioblastomas Open

Jaejoon Lim, Sohyun Hwang, Haeyoun Kang, Jin Hyung Heo, Ah‐Young Kwon , et al. · 2022

Planning for Innovation in the Quality Assessment System of Healthcare Benefits Open

Sang Ji Kim, Sook Kyoung Jun, Chang Weon Lee, Young Ae Jeong, Jae-Young Ahn , et al. · 2021

Sang Ji Kim, Sook Kyoung Jun, Chang Weon Lee, Young Ae Jeong, Jae-Young Ahn, You Me An, Ah-Young Kwon, Sang Hee Lim, Jeong Nam Choi, Mi Sun Yun, Eui Hyeong Byun, Mee Hyeon Cho. HIRA Research 2021;1:132-42. https://doi.org/10.52937/hira.21.…

USP19 and RPL23 as Candidate Prognostic Markers for Advanced-Stage High-Grade Serous Ovarian Carcinoma Open

Haeyoun Kang, Min Chul Choi, Sewha Kim, Ju‐Yeon Jeong, Ah‐Young Kwon , et al. · 2021

Ovarian cancer is one of the leading causes of deaths among patients with gynecological malignancies worldwide. In order to identify prognostic markers for ovarian cancer, we performed RNA-sequencing and analyzed the transcriptome data fro…

Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function Open

Ye-Jin Park, Sungkyung Kim, Hyeon‐Pyo Shim, Jae H. Park, Gyunghee Lee , et al. · 2021

The Prognostic Impact of HER2 Genetic and Protein Expression in Pancreatic Carcinoma—HER2 Protein and Gene in Pancreatic Cancer Open

Song‐Hee Han, Ki Hyun Ryu, Ah‐Young Kwon · 2021

Pancreatic ductal adenocarcinoma (PDAC) is a lethal and clinically heterogeneous disease with a limited benefit from human epidermal growth factor receptor 2 (HER2)-targeted therapy. Recently, some studies have addressed the antitumoral ef…

Clinical Impact of Natural Killer Group 2D Receptor Expression and That of Its Ligand in Ovarian Carcinomas: A Retrospective Study Open

Gee Hoon Lee, Hee Jung An, Tae Hoen Kim, Gwangil Kim, Kyung‐Soon Park , et al. · 2021

High expression of ULBP1 predicts a better prognosis for HGSC, suggesting that ULBP1 expression could be a novel prognostic indicator in this subset of carcinomas.

Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model Open

Nahee Park, Kamal Pandey, Sei Kyung Chang, Ah‐Young Kwon, Young Bin Cho , et al. · 2020

Background Well-characterized preclinical models are essential for immune-oncology research. We investigated the feasibility of our humanized mouse model for evaluating the long-term efficacy of immunotherapy and biomarkers. Methods Humani…

Immune gene signatures for predicting durable clinical benefit of anti-PD-1 immunotherapy in patients with non-small cell lung cancer Open

Sohyun Hwang, Ah‐Young Kwon, Ju‐Yeon Jeong, Sewha Kim, Haeyoun Kang , et al. · 2020

Practical approaches to automated digital image analysis of Ki-67 labeling index in 997 breast carcinomas and causes of discordance with visual assessment Open

Ah‐Young Kwon, Ha Young Park, Jiyeon Hyeon, Seok Jin Nam, Seok Won Kim , et al. · 2019

The Ki-67 labeling index (LI) is an important prognostic factor in breast carcinoma. The Ki-67 LI is traditionally calculated via unaided microscopic estimation; however, inter-observer and intra-observer variability and low reproducibilit…

Mutations of the <i>Gongpo</i> Gene Encoding a Homolog of Mammalian Phosphatidylserine Synthases Cause Neurodegeneration in <i>Drosophila Melanogaster</i> Open

Ye-Jin Park, Sungkyung Kim, Hyeon‐Pyo Shim, Jae H. Park, Gyunghee Lee , et al. · 2019

Cytologic Characteristics of Thymic Adenocarcinoma with Enteric Differentiation: A Study of Four Fine-Needle Aspiration Specimens Open

Ah‐Young Kwon, Joungho Han, Haeyon Cho, Seokhwi Kim, Heejin Bang , et al. · 2017

Thymic adenocarcinoma is extremely rare. Although its histologic features have been occasionally reported, a lack of description of the cytologic features has hampered the prompt and accurate diagnosis of this condition. Herein, we describ…

Fascin expression is inversely correlated with breast cancer metastasis suppressor 1 and predicts a worse survival outcome in node-negative breast cancer patients Open

Hye Jin Lee, Hee Jung An, Tae Hoen Kim, Gwangil Kim, Haeyoun Kang , et al. · 2017

Background: Fascin is an actin-bundling protein that promotes cancer cell migration and invasion. By contrast, breast cancer metastasis suppressor 1 (BRMS1) inhibits cancer metastasis by targeting multiple steps of the metastatic ca…

Is the panoramic mandibular index useful for bone quality evaluation? Open

Ah‐Young Kwon, Kyung‐Hoe Huh, Won-Jin Yi, Sam-Sun Lee, Soon-Chul Choi , et al. · 2017

Purpose:The aim of this study was to determine whether the panoramic mandibular index (PMI) is useful for assessing bone mineral density.We also analyzed the potential correlations between PMI parameters and patient age.Materials and Metho…

An Ancillary CT Finding of Intrapulmonary Solitary Fibrous Tumor: A Case Report Open

Dong-Jun Lee, Ji Young Rho, Ah‐Young Kwon · 2017

Intrapulmonary solitary fibrous tumor is extremely rare. A few reports have presented typical CT findings such as well-defined, variable—sized, heterogeneously or homogenously well-enhanced intrapulmonary nodules. We report herein a rare c…

Haemophilic pseudotumour in two parts of the maxilla: case report Open

Ah‐Young Kwon, Kyung‐Hoe Huh, Won-Jin Yi, Khanthaly Symkhampha, Min-Suk Heo , et al. · 2016

Haemophilic pseudotumour is a rare disease that occurs most often in femur, tibia, ilium or pelvic bone of a patient with haemophilia. Thus far, there have been only 31 reported cases in jaw bones and paranasal sinuses. Among them, the man…

Pulmonary Placental Transmogrification Presenting as a Small Lung Nodule Open

Hak Su Kim, Ji‐Hyun Lee, Hye Cheol Jeong, Jung‐Hyun Kim, Su Hyung Park , et al. · 2016

Pulmonary placental transmogrification (PT) is a rare lung disease that takes on the histologic appearance of placental chorionic villi. We herein report a case of PT in a 66-year-old woman who presented with a single nodule on chest radio…

Intrahepatic Cholangiocarcinoma with Ductal Plate Malformation-like Feature Associated with Bile Duct Adenoma Open

Ah‐Young Kwon, Hye Jin Lee, Hee Jung An, Haeyoun Kang, Jin Hyung Heo , et al. · 2015

Intrahepatic cholangiocarcinoma (ICC) is a malignant tumor with biliary epithelial differentiation. Malignant transformation of von Meyenburg complex (VMC) to ICC has been reported [1,2], and a new subtype of ICC with ductal plate malforma…

VAV3 Overexpressed in Cancer Stem Cells Is a Poor Prognostic Indicator in Ovarian Cancer Patients Open

Ah‐Young Kwon, Gwangil Kim, Ju‐Yeon Jeong, Ji-Ye Song, Kyu-Beom Kwack , et al. · 2015

Ovarian carcinoma is a highly lethal malignancy due to frequent relapse and drug resistance. Cancer stem cells (CSCs) are thought to contribute significantly to disease relapse and drug resistance. In this study, a subpopulation of CSCs of…

Endobronchial ALK-Positive Anaplastic Large Cell Lymphoma Presenting Massive Hemoptysis Open

Hee Kyung Kim, Bo Hye Kim, Sae Ahm Kim, Jae Kyoung Shin, Ji-Hyun Song , et al. · 2015

Primary anaplastic large cell lymphoma (ALCL) of the lung is highly aggressive and quite rare. We report here a case of anaplastic lymphoma kinase-positive endobronchial ALCL, that was initially thought to be primary lung cancer. A 68-year…

A Case of Benign Vascular Tumor of Tympanic Membrane Open

Young Ju Kim, Ah‐Young Kwon, Hyoung‐Mi Kim · 2015

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