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View article: Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism
Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism Open
Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP), a significant global health burden. While glycosylation plays a key role in cellular signaling and inflammation, its role in IVD degeneration remains poorly un…
View article: AI assisted video analysis of the Trendelenburg Test: A Feasibility Study
AI assisted video analysis of the Trendelenburg Test: A Feasibility Study Open
Background: The Trendelenburg test is widely used to assess hip abductor function but is traditionally graded as a binary sign, limiting sensitivity and reliability. Compensatory trunk lean may mask pelvic drop and further reduces diagnost…
View article: Patterns of intra-discal vacuum phenomenon in adult degenerative scoliosis
Patterns of intra-discal vacuum phenomenon in adult degenerative scoliosis Open
CT analysis of degenerative scoliosis demonstrates predominantly multilevel contralateral asymmetric IDVP, with increased involvement of the upper lumbar spine and formation of S-shape curves, identifying a coronal compensatory correction …
View article: Intra-discal vacuum phenomenon with advanced lumbar spine disc degeneration: complementary findings from both MRI and CT
Intra-discal vacuum phenomenon with advanced lumbar spine disc degeneration: complementary findings from both MRI and CT Open
View article: Assessment and early investigation of cauda equina syndrome- a systematic review of existing international guidelines and summary of the current evidence
Assessment and early investigation of cauda equina syndrome- a systematic review of existing international guidelines and summary of the current evidence Open
Background context Cauda Equina Syndrome (CES) is an emergency clinical syndrome with correlating radiological evidence of spinal compression. Urgent recognition and treatment is key. In many units, it lacks a clear pathway of investigatio…
View article: An investigation of composition, morphology, mechanical properties, and microdamage accumulation of human type 2 diabetic bone
An investigation of composition, morphology, mechanical properties, and microdamage accumulation of human type 2 diabetic bone Open
This study investigates the biomechanics of type 2 diabetic bone fragility through a multiscale experimental strategy that considers structural, mechanical, and compositional components of ex vivo human trabecular and cortical bone. Human …
View article: Bilateral tibial fractures associated with powered exoskeleton use in complete spinal cord injury – a case report & literature review
Bilateral tibial fractures associated with powered exoskeleton use in complete spinal cord injury – a case report & literature review Open
View article: Unravelling the glycome in human intervertebral disc degeneration: Aberrant glycosylation modulates inflammation and metabolism
Unravelling the glycome in human intervertebral disc degeneration: Aberrant glycosylation modulates inflammation and metabolism Open
Intervertebral disc (IVD) degeneration is one of the major contributing causes of low back pain (LBP), a common health issue that imposes a significant socio-economic burden on society. Previous work has demonstrated a dysregulated glycome…
View article: Intradiscal vacuum phenomenon matches lumbar spine degeneration patterns in an ageing population
Intradiscal vacuum phenomenon matches lumbar spine degeneration patterns in an ageing population Open
Purpose Intra-Discal Vacuum phenomenon (IDVP) is well-recognised, yet poorly visualised and poorly understood radiological finding in disc degeneration, particularly with regard to its role in spinal alignment. CT analysis of the lumbar sp…
View article: Lumbar spine disc degeneration and intradiscal vacuum phenomenon : Complementary findings from CT and MRI
Lumbar spine disc degeneration and intradiscal vacuum phenomenon : Complementary findings from CT and MRI Open
View article: Is vacuum disc phenomenon associated with spinal morphology ?
Is vacuum disc phenomenon associated with spinal morphology ? Open
View article: When spinal instrumentation revision is not an option: Salvage vertebral augmentation with polymethylmethacrylate for mechanical complications: A systematic review
When spinal instrumentation revision is not an option: Salvage vertebral augmentation with polymethylmethacrylate for mechanical complications: A systematic review Open
View article: Review of the Role of Intraoperative Neurophysiological Monitoring in Spinal Surgery With a Focus on the True and False Positives and a Clinical Correlation
Review of the Role of Intraoperative Neurophysiological Monitoring in Spinal Surgery With a Focus on the True and False Positives and a Clinical Correlation Open
BACKGROUND: Spinal surgery is a technically challenging endeavor with potentially devastating complications. Intraoperative neurophysiological monitoring (IONM) is a method of preventing and identifying damage to the spinal cord. OBJECTIVE…
View article: Intervertebral Disc Degeneration: Biomaterials and Tissue Engineering Strategies toward Precision Medicine
Intervertebral Disc Degeneration: Biomaterials and Tissue Engineering Strategies toward Precision Medicine Open
Intervertebral disc degeneration is a common cause of discogenic low back pain resulting in significant disability. Current conservative or surgical intervention treatments do not reverse the underlying disc degeneration or regenerate the …
View article: Assessing the accuracy of measuring leg length discrepancy and genu varum/valgum using a markerless motion analysis system
Assessing the accuracy of measuring leg length discrepancy and genu varum/valgum using a markerless motion analysis system Open
View article: AB068. SOH21AS131. A retrospective analysis of radiation exposure to patients during orthopaedic fluoroscopic nerve block procedures: can we lessen the dose?
AB068. SOH21AS131. A retrospective analysis of radiation exposure to patients during orthopaedic fluoroscopic nerve block procedures: can we lessen the dose? Open
Background: This study investigates radiation doses received by patients undergoing transforaminal (TFNB), hip, and sacroiliac joint (SIJ) nerve blocks by a single consultant orthopaedic surgeon across two separate settings: Theatre vs. Ca…
View article: AB096. SOH21AS199. Joint replacement surgery waiting times in a major tertiary referral centre: perceptions and expectations
AB096. SOH21AS199. Joint replacement surgery waiting times in a major tertiary referral centre: perceptions and expectations Open
Background: Information regarding the exact waiting time for an elective joint arthroplasty (total hip and knee replacement) is not widely available in Ireland. In particular, the waiting time from general practitioner (GP) referral to bei…
View article: The role of altered glycosylation in human nucleus pulposus cells in inflammation and degeneration
The role of altered glycosylation in human nucleus pulposus cells in inflammation and degeneration Open
Intervertebral disc (IVD) degeneration causes low-back pain through disc compression, prolapse and herniation. Inflammation of the IVD and subsequent degeneration produce altered glycosylation profiles in several animal models of IVD injur…
View article: Ten Inventions That Shaped Modern Orthopedics
Ten Inventions That Shaped Modern Orthopedics Open
The current field of orthopedics is the result of many decades of minor and major advancements. The evolution of orthopedics has culminated into the modern field seen today. This article presents 10 inventions that played a key role in sha…
View article: A randomised controlled trial of SAFMEDS to improve musculoskeletal radiology interpretation
A randomised controlled trial of SAFMEDS to improve musculoskeletal radiology interpretation Open
SAFMEDS constitutes a powerful adjunct to usual teaching that produces significant improvement with a short duration of engagement, particularly when students achieve fluency in the target behaviour. Future research should consider the app…
View article: Augmented, virtual and mixed reality in spinal surgery: A real-world experience
Augmented, virtual and mixed reality in spinal surgery: A real-world experience Open
This review aims to identify the role of augmented, virtual or mixed reality (AR, VR or MR) technologies in setting of spinal surgery. The authors address the challenges surrounding the implementation of this technology in the operating ro…
View article: AB158. An analysis of implant related waste in the Trauma and Orthopaedics Department of Galway University Hospital
AB158. An analysis of implant related waste in the Trauma and Orthopaedics Department of Galway University Hospital Open
Background: Medical waste contributes a significant burden to our environment and operating theaters have been shown to disproportionately contribute to healthcare associated waste. In orthopaedics and trauma, a portion of this comes from …
View article: AB263. Expectations of waiting times for joint arthroplasty in an Irish hospital
AB263. Expectations of waiting times for joint arthroplasty in an Irish hospital Open
Background: Information regarding the exact waiting time for an elective joint arthroplasty (total hip replacement and total knee replacement) is not widely available. Thus far, there is no published data as regards the waiting time from g…
View article: Prolonged acidosis is a feature of SGLT2i-induced euglycaemic diabetic ketoacidosis
Prolonged acidosis is a feature of SGLT2i-induced euglycaemic diabetic ketoacidosis Open
Summary We describe two cases of SGLT2i-induced euglycaemic diabetic ketoacidosis, which took longer than we anticipated to treat despite initiation of our DKA protocol. Both patients had an unequivocal diagnosis of type 2 diabetes, had po…
View article: Current concepts and an update on the surgical management of metastasis to the sacral spine
Current concepts and an update on the surgical management of metastasis to the sacral spine Open
This review article endeavors to provide an update on the current concepts pertaining to the presentation, investigation, and management of sacral metastases. A review of the English language literature from 1995 to 2015 was undertaken. Pu…
View article: Signs of Nature in Spine Radiology
Signs of Nature in Spine Radiology Open
View article: AB039. 154. Retrospective cohort study: transforaminal nerve block injection- the association between body mass index and the depth of epidural space, radiation dose exposure and fluoroscopic screening time
AB039. 154. Retrospective cohort study: transforaminal nerve block injection- the association between body mass index and the depth of epidural space, radiation dose exposure and fluoroscopic screening time Open
AB039. 154. Retrospective cohort study: transforaminal nerve block injection- the association between body mass index and the depth of epidural space, radiation dose exposure and fluoroscopic screening time
View article: Dural ectasia associated with Mounier-Kuhn syndrome: a novel association in the context of spinal stenosis
Dural ectasia associated with Mounier-Kuhn syndrome: a novel association in the context of spinal stenosis Open
We present the case of a patient undergoing lumbar spine decompression for stenosis with a history of Mounier-Kuhn syndrome. The patient presented with axial lumbar spine pain over 6 months with progressive radicular pain to the left L3 de…
View article: Spinal Metastatic Disease: A Review of the Role of the Multidisciplinary Team
Spinal Metastatic Disease: A Review of the Role of the Multidisciplinary Team Open
Historically, a simple approach centered on palliation was applicable to the majority of patients with metastatic spinal disease. With advances in diagnosis and treatment, a more complicated algorithm has devolved requiring a multidiscipli…
View article: Sternal metastasis - the forgotten column and its effect on thoracic spine stability
Sternal metastasis - the forgotten column and its effect on thoracic spine stability Open
Sternal metastases are not studied extensively in the literature. There is a paucity of information on their role in metastatic disease. The concept of the fourth column was described by Berg in 1993, and has been proven in case report, cl…