Aijie Liu
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View article: The association between potassium level during the anhepatic stage of orthotopic liver transplantation and postoperative acute kidney injury: an exploratory study
The association between potassium level during the anhepatic stage of orthotopic liver transplantation and postoperative acute kidney injury: an exploratory study Open
View article: The association between triglyceride glucose–body mass index and all–cause mortality in critically ill patients undergoing cardiac surgery: a retrospective analysis from the MIMIC–IV database
The association between triglyceride glucose–body mass index and all–cause mortality in critically ill patients undergoing cardiac surgery: a retrospective analysis from the MIMIC–IV database Open
View article: 36 | FREQUENCY OF FUSION GENES AND THEIR CLINICAL IMPACTS IN CHINESE PEDIATRIC PATIENTS WITH T‐CELL LYMPHOBLASTIC LYMPHOMA
36 | FREQUENCY OF FUSION GENES AND THEIR CLINICAL IMPACTS IN CHINESE PEDIATRIC PATIENTS WITH T‐CELL LYMPHOBLASTIC LYMPHOMA Open
View article: Isolation and identification of components of mother liquor sugar from Stevia rebaudiana Bertoni with nematicidal activity
Isolation and identification of components of mother liquor sugar from Stevia rebaudiana Bertoni with nematicidal activity Open
View article: Lactobacillus fermentum CKCC1858 and Lactobacillus plantarum CKCC1312 ameliorate the symptoms of ulcerative colitis in mouse model induced by dextran sulfate sodium
Lactobacillus fermentum CKCC1858 and Lactobacillus plantarum CKCC1312 ameliorate the symptoms of ulcerative colitis in mouse model induced by dextran sulfate sodium Open
The objective of this study was to investigate the therapeutical action of Lactobacillus fermentum CKCC1858 and Lactobacillus plantarum CKCC1312 on ulcerative colitis (UC) and its mechanism. The results showed that L. fermentum CKCC1858 an…
View article: Beneficial effect of <i>Lactobacillus fermentum</i> GLF‐217 on hyperlipidemia in high‐fat diet golden hamsters by regulating gut microbiota
Beneficial effect of <i>Lactobacillus fermentum</i> GLF‐217 on hyperlipidemia in high‐fat diet golden hamsters by regulating gut microbiota Open
To investigate the hypolipidemic and modulation effects of probiotics, the golden hamster of hyperlipidemia model was established and intervened with Lactobacillus fermentum GLF‐217 (GLF‐217) and lovastatin (LOV) for 6 weeks. Body weight a…
View article: LANDSCAPE OF DRIVER MUTATIONS AND THEIR CLINICAL IMPACTS IN CHINESE PEDIATRIC PATIENTS WITH MATURE B‐CELL NON‐HODGKIN'S LYMPHOMA AND T‐CELL LYMPHOBLASTIC LYMPHOMA
LANDSCAPE OF DRIVER MUTATIONS AND THEIR CLINICAL IMPACTS IN CHINESE PEDIATRIC PATIENTS WITH MATURE B‐CELL NON‐HODGKIN'S LYMPHOMA AND T‐CELL LYMPHOBLASTIC LYMPHOMA Open
Introduction: Mature B-cell non-Hodgkin's lymphoma (MB-NHL) and T-cell lymphoblastic lymphoma (T-LBL) account for ∼50% and ∼20%, respectively, among the different pediatric NHL entities. Our understanding of the genetic lesions and profili…
View article: ANALYSIS TREATMENT OUTCOME OF 46 REFRACTORY/RELAPSED PEDIATRIC MATURE B CELL LYMPHOMA PATIENTS‐MULTI‐CENTER EXPERIENCE FROM CHINA
ANALYSIS TREATMENT OUTCOME OF 46 REFRACTORY/RELAPSED PEDIATRIC MATURE B CELL LYMPHOMA PATIENTS‐MULTI‐CENTER EXPERIENCE FROM CHINA Open
Introduction: Aim to find the efficacy treatment strategy for refractory/relapsed(r/r) patients with pediatric mature B-cell lymphoma (MBL) by summarizing the treatment outcome of 46 patients from Chinese Children's Lymphoma Multi-center C…
View article: Supplemental Figures S1-4 from Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage
Supplemental Figures S1-4 from Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage Open
Supplemental Figures S1-4. Supplementary Figure S1: eRapa prevents DMBA/TPA-induced dermal neoplasia and malignant degeneration in WT mice. Supplementary Figure S2: eRapa does not suppress mTORC1 signaling in whole skin. Supplementary Figu…
View article: Supplemental Figures S1-4 from Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage
Supplemental Figures S1-4 from Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage Open
Supplemental Figures S1-4. Supplementary Figure S1: eRapa prevents DMBA/TPA-induced dermal neoplasia and malignant degeneration in WT mice. Supplementary Figure S2: eRapa does not suppress mTORC1 signaling in whole skin. Supplementary Figu…
View article: Supplementary Data from CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade
Supplementary Data from CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade Open
Supplementary figures 1-10. Figure S1. IL-2c increases conventional CD4 T cell in ascites three weeks after final IL-2c, but does not affect ascites Treg and effector T cell numbers at one week after final IL-2c administration. Figure S2. …
View article: Supplementary Figures 1 through 11 from Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment
Supplementary Figures 1 through 11 from Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment Open
Supplementary figure 1. Rapamycin reduces EL4 bone marrow infiltration. Supplementary figure 2. HD rapamycin impairs T cell activation and infiltration. Supplementary figure 3. Effects of rapamycin on mTOR signals and Ki67 (proliferation) …
View article: Data from Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment
Data from Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment Open
mTOR drives tumor growth but also supports T-cell function, rendering the applications of mTOR inhibitors complex especially in T-cell malignancies. Here, we studied the effects of the mTOR inhibitor rapamycin in mouse EL4 T-cell lymphoma.…
View article: Supplementary Figures 1 through 11 from Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment
Supplementary Figures 1 through 11 from Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment Open
Supplementary figure 1. Rapamycin reduces EL4 bone marrow infiltration. Supplementary figure 2. HD rapamycin impairs T cell activation and infiltration. Supplementary figure 3. Effects of rapamycin on mTOR signals and Ki67 (proliferation) …
View article: Supplementary Data from CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade
Supplementary Data from CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade Open
Supplementary figures 1-10. Figure S1. IL-2c increases conventional CD4 T cell in ascites three weeks after final IL-2c, but does not affect ascites Treg and effector T cell numbers at one week after final IL-2c administration. Figure S2. …
View article: Supplementary Figures 1-7 from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
Supplementary Figures 1-7 from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression Open
Supplementary Figures 1-7 from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
View article: Supplementary Methods from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
Supplementary Methods from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression Open
Supplementary Methods from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
View article: Supplementary Figures 1-7 from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
Supplementary Figures 1-7 from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression Open
Supplementary Figures 1-7 from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
View article: Supplementary Methods from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
Supplementary Methods from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression Open
Supplementary Methods from CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
View article: PCDH19-related epilepsy in mosaic males: The phenotypic implication of genotype and variant allele frequency
PCDH19-related epilepsy in mosaic males: The phenotypic implication of genotype and variant allele frequency Open
Objective To analyze the genotypes and phenotypes of mosaic male patients with PCDH19 -related epilepsy ( PCDH19 -RE) and explore the correlation between genotype, variant allele frequency (VAF), and phenotypic severity. Methods Clinical d…
View article: Natural history and genetic study of LAMA2-related muscular dystrophy in a large Chinese cohort
Natural history and genetic study of LAMA2-related muscular dystrophy in a large Chinese cohort Open
View article: Characterization of an Antiviral Component in Human Seminal Plasma
Characterization of an Antiviral Component in Human Seminal Plasma Open
Numerous types of viruses have been found in human semen, which raises concerns about the sexual transmission of these viruses. The overall effect of semen on viral infection and transmission have yet to be fully investigated. In the prese…
View article: Supplementary Material for: Relationship between Serum Uric Acid and Mortality Risk in Hemodialysis Patients: A Multicenter Prospective Cohort Study
Supplementary Material for: Relationship between Serum Uric Acid and Mortality Risk in Hemodialysis Patients: A Multicenter Prospective Cohort Study Open
Background: Several studies have reported that low serum uric acid (SUA) levels are related to increased risk of mortality in maintenance hemodialysis (MHD) patients. However, the possible detrimental effects of high SUA on t…
View article: <i>CHD2</i>‐related epilepsy: novel mutations and new phenotypes
<i>CHD2</i>‐related epilepsy: novel mutations and new phenotypes Open
The aim of this report was to refine the genotypes and phenotypes of chromodomain helicase DNA‐binding protein 2 ( CHD2 )‐related epilepsy. Seventeen patients with CHD2 mutations were enrolled. CHD2 mutations were identified by application…
View article: Mosaicism and incomplete penetrance of <i>PCDH19</i> mutations
Mosaicism and incomplete penetrance of <i>PCDH19</i> mutations Open
Background Mutations in the PCDH19 gene have mainly been reported in female patients with epilepsy. To date, PCDH19 mutations have been reported in hundreds of females and only in 10 mosaic male epileptic patients with mosaicism. Objective…
View article: Deletion of exon 4 in LAMA2 is the most frequent mutation in Chinese patients with laminin α2-related muscular dystrophy
Deletion of exon 4 in LAMA2 is the most frequent mutation in Chinese patients with laminin α2-related muscular dystrophy Open
View article: The clinical outcome and neuroimaging of acute encephalopathy after status epilepticus in Dravet syndrome
The clinical outcome and neuroimaging of acute encephalopathy after status epilepticus in Dravet syndrome Open
Aim To analyze the clinical outcome and neuroimaging over a long duration follow‐up in the currently largest series of acute encephalopathy after status epilepticus in patients with Dravet syndrome. Method Clinical and neuroimaging data of…
View article: Severe infantile onset developmental and epileptic encephalopathy caused by mutations in autophagy gene <i><scp>WDR</scp>45</i>
Severe infantile onset developmental and epileptic encephalopathy caused by mutations in autophagy gene <i><span>WDR</span>45</i> Open
Summary Heterozygous de novo variants in the autophagy gene, WDR 45 , are found in beta‐propeller protein‐associated neurodegeneration ( BPAN ). BPAN is characterized by adolescent onset dementia and dystonia; 66% patients have seizures. W…
View article: Genetic analysis of benign familial epilepsies in the first year of life in a Chinese cohort
Genetic analysis of benign familial epilepsies in the first year of life in a Chinese cohort Open
View article: Genomic mosaicism in paternal sperm and multiple parental tissues in a Dravet syndrome cohort
Genomic mosaicism in paternal sperm and multiple parental tissues in a Dravet syndrome cohort Open