Aina Rill
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View article: Patient-derived liver organoids recapitulate liver epithelial heterogeneity and enable precision modeling of alcohol-related liver disease
Patient-derived liver organoids recapitulate liver epithelial heterogeneity and enable precision modeling of alcohol-related liver disease Open
View article: Hepatocyte–Neutrophil Interaction in the Liver via SAA-FPR2 Is Key in the Pathogenesis of Alcohol-Associated Hepatitis
Hepatocyte–Neutrophil Interaction in the Liver via SAA-FPR2 Is Key in the Pathogenesis of Alcohol-Associated Hepatitis Open
View article: Patient-derived liver biopsy organoids enable precision alcohol-associated liver disease modeling
Patient-derived liver biopsy organoids enable precision alcohol-associated liver disease modeling Open
Background & Aims Alcohol-associated liver disease (ALD) is a major cause of liver disease worldwide with scarce therapeutic options. Animal models poorly recapitulate advanced ALD precluding the development of new treatments. Organoids ha…
View article: Convergent evolution of complex adaptive traits modulates angiogenesis in high-altitude Andean and Himalayan human populations
Convergent evolution of complex adaptive traits modulates angiogenesis in high-altitude Andean and Himalayan human populations Open
View article: Author Correction: Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease
Author Correction: Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease Open
View article: Convergent evolution of complex adaptive traits enabled human life at high altitudes
Convergent evolution of complex adaptive traits enabled human life at high altitudes Open
Convergent adaptations represent paradigmatic examples of the capacity of natural selection to influence organisms’ biology. However, the possibility to investigate genetic determinants underpinning convergent complex adaptive traits has b…
View article: Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease
Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease Open
View article: Macrophage and neutrophil heterogeneity at single-cell spatial resolution in inflammatory bowel disease
Macrophage and neutrophil heterogeneity at single-cell spatial resolution in inflammatory bowel disease Open
Ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory intestinal diseases that show a perplexing heterogeneity in manifestations and response to treatment. The molecular basis for this heterogeneity remains uncharacteri…