Aïna Venkatasamy
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View article: Microscopic assessment of lymph node status in gynecological malignancies using full-field optical coherence tomography
Microscopic assessment of lymph node status in gynecological malignancies using full-field optical coherence tomography Open
View article: 7-T MRI-based surrogate for histopathology examination of liver fibrosis
7-T MRI-based surrogate for histopathology examination of liver fibrosis Open
View article: Perilymphatic Signal Changes in Vestibular Schwannoma: A Potential Biomarker of Progressive Hearing Loss?
Perilymphatic Signal Changes in Vestibular Schwannoma: A Potential Biomarker of Progressive Hearing Loss? Open
Objective Vestibular schwannomas influence the magnetic resonance (MR) signal intensity (SI) in the vestibular cistern and cochlear perilymph. The aim of this study is to evaluate the relationship between perilymphatic signal changes on gr…
View article: Secondary endolymphatic hydrops: a clinical and literature overview
Secondary endolymphatic hydrops: a clinical and literature overview Open
Introduction and importance Secondary endolymphatic hydrops (SEH) is a pathologic condition of the inner ear that usually manifests as episodic vertigo and fluctuating hearing loss, overlapping with other temporal bone pathologies and inne…
View article: Characterization of the ciliary beating efficiency in primary diffuse chronic rhinosinusitis
Characterization of the ciliary beating efficiency in primary diffuse chronic rhinosinusitis Open
Ciliary dysfunction may result in chronic airway inflammation and infection causing injury and structural changes to the airway epithelium, leading to a variety of diseases, like bronchiectasis and primary diffuse chronic rhinosinusitis (C…
View article: The unfolded protein response-glutathione metabolism axis: A novel target of a cycloruthenated complexes bypassing tumor resistance mechanisms
The unfolded protein response-glutathione metabolism axis: A novel target of a cycloruthenated complexes bypassing tumor resistance mechanisms Open
View article: Post-cholecystectomy biliary leakage mimicking a neoplastic lesion: contribution of cholangioscopy in diagnosis and endoscopic treatment
Post-cholecystectomy biliary leakage mimicking a neoplastic lesion: contribution of cholangioscopy in diagnosis and endoscopic treatment Open
International audience
View article: Morpho-functional analysis of patient-derived xenografts reveals differential impact of gastric cancer and chemotherapy on the tumor ecosystem, affecting immune check point, metabolism, and sarcopenia
Morpho-functional analysis of patient-derived xenografts reveals differential impact of gastric cancer and chemotherapy on the tumor ecosystem, affecting immune check point, metabolism, and sarcopenia Open
Objectives Gastric cancer (GC) is an aggressive disease due to late diagnosis resulting from the lack of easy diagnostic tools, resistances toward immunotherapy (due to low PD-L1 expression), or chemotherapies (due to p53 mutations), and c…
View article: Sarcopenia remaining after intensive nutritional feeding support could be a criterion for the selection of patients for surgery for oesogastric junction adenocarcinoma
Sarcopenia remaining after intensive nutritional feeding support could be a criterion for the selection of patients for surgery for oesogastric junction adenocarcinoma Open
View article: High-resolution (7-T) Liver MRI for Pathologic Examination
High-resolution (7-T) Liver MRI for Pathologic Examination Open
No abstract available
View article: Evaluation of the anal canal using diffusion tensor imaging (DTI) with fiber tractography: prospective study of treated perianal fistula
Evaluation of the anal canal using diffusion tensor imaging (DTI) with fiber tractography: prospective study of treated perianal fistula Open
Background: To prospectively evaluate the post-therapeutic aspects of the anal canal on MRI using diffusion tensor imaging (DTI) with tractography in healed perianal fistula. Methods: From September 2019 to August 2021, we included 21 pati…
View article: Conventional and artificial intelligence-based imaging for biomarker discovery in chronic liver disease
Conventional and artificial intelligence-based imaging for biomarker discovery in chronic liver disease Open
View article: Multicentric evaluation of a 3D‐printed simulator for COVID- 19 nasopharyngeal swab collection in testing centers
Multicentric evaluation of a 3D‐printed simulator for COVID- 19 nasopharyngeal swab collection in testing centers Open
View article: Ultrasound and Transcriptomics Identify a Differential Impact of Cisplatin and Histone Deacetylation on Tumor Structure and Microenvironment in a Patient-Derived In Vivo Model of Gastric Cancer
Ultrasound and Transcriptomics Identify a Differential Impact of Cisplatin and Histone Deacetylation on Tumor Structure and Microenvironment in a Patient-Derived In Vivo Model of Gastric Cancer Open
The reasons behind the poor efficacy of transition metal-based chemotherapies (e.g., cisplatin) or targeted therapies (e.g., histone deacetylase inhibitors, HDACi) on gastric cancer (GC) remain elusive and recent studies suggested that the…
View article: Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exciting Long-Term Collaboration with Dr. Michel Pfeffer
Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exciting Long-Term Collaboration with Dr. Michel Pfeffer Open
Metal complexes have been used to treat cancer since the discovery of cisplatin and its interaction with DNA in the 1960’s. Facing the resistance mechanisms against platinum salts and their side effects, safer therapeutic approaches have b…
View article: Current Clinical and Pre-Clinical Imaging Approaches to Study the Cancer-Associated Immune System
Current Clinical and Pre-Clinical Imaging Approaches to Study the Cancer-Associated Immune System Open
In the light of the success and the expected growth of its arsenal, immuno-therapy may become the standard neoadjuvant procedure for many cancers in the near future. However, aspects such as the identity, organization and the activation st…
View article: Present and future of the labyrinth imaging: Focus on the use of T2-weighted and contrast-enhanced delayed FLAIR (1 h) sequences
Present and future of the labyrinth imaging: Focus on the use of T2-weighted and contrast-enhanced delayed FLAIR (1 h) sequences Open
OBJECTIVE: Part of the recent progress in the labyrinth imaging has been made possible by the rise of contrast-free T2-weighted and delayed (1h) FLAIR sequences. The aim of this article is to review evidence for the use of these two sequen…
View article: Clinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis
Clinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis Open
This cohort study examines the clinical course and prognosis of patients with COVID-19–related anosmia for 1 year after diagnosis.
View article: Pharmacological Inhibition of mTORC2 Reduces Migration and Metastasis in Melanoma
Pharmacological Inhibition of mTORC2 Reduces Migration and Metastasis in Melanoma Open
Despite recent advances in therapy, liver metastasis from melanoma is still associated with poor prognosis. Although targeting the mTOR signaling pathway exerts potent anti-tumor activity, little is known about specific mTORC2 inhibition r…
View article: Développement et utilistaion d'outils d'analyses précliniques pour le traitement du cancer de l'estomac
Développement et utilistaion d'outils d'analyses précliniques pour le traitement du cancer de l'estomac Open
Gastric cancer is a complex and heterogeneous cancer with a poor prognosis, for which there is currently no truly effective targeted therapy. During my thesis, I have developed and maintained 5 different patient-derived xenografts (PDX), w…
View article: Acute smell and taste loss in outpatients: all infected with SARS-CoV-2?
Acute smell and taste loss in outpatients: all infected with SARS-CoV-2? Open
During SARS-CoV-2 pandemic, our region (Alsace, East of France) became a Covid-19 cluster quite early in Europe. Loss of smell and taste was quickly flagged by the Ears-Nose and Throat scientific community as a potential warning signs of S…
View article: HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway
HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway Open
Gastric cancer (GC) remains a health issue due to the low efficiency of therapies, such as cisplatin. This unsatisfactory situation highlights the necessity of finding factors impacting GC sensibility to therapies. We analyzed the cisplati…
View article: 3D finite element model of posterior membranous labyrinth from in vivo MRI of human temporal bone, including sensory zones
3D finite element model of posterior membranous labyrinth from in vivo MRI of human temporal bone, including sensory zones Open
Objective: The aim of this work is to create a three-dimensional (3D) finite element model (FEM) of the human posterior membranous labyrinth, based on in vivo inner ear magnetic resonance imaging (MRI). Study design and setting:We used T2 …
View article: Imaging of the saccule for the diagnosis of endolymphatic hydrops in Meniere disease, using a three-dimensional T2-weighted steady state free precession sequence: accurate, fast, and without contrast material intravenous injection
Imaging of the saccule for the diagnosis of endolymphatic hydrops in Meniere disease, using a three-dimensional T2-weighted steady state free precession sequence: accurate, fast, and without contrast material intravenous injection Open
View article: Differentiation of vestibular schwannomas from meningiomas of the internal auditory canal using perilymphatic signal evaluation on T2-weighted gradient-echo fast imaging employing steady state acquisition at 3T
Differentiation of vestibular schwannomas from meningiomas of the internal auditory canal using perilymphatic signal evaluation on T2-weighted gradient-echo fast imaging employing steady state acquisition at 3T Open
View article: Surgical management of a De Garengeot’s hernia using a biologic mesh: A case report and review of literature
Surgical management of a De Garengeot’s hernia using a biologic mesh: A case report and review of literature Open
View article: Imaging of the congenital anomalies of the facial nerve: how to make sure your favorite surgeon does not hit CN7 during his procedure?
Imaging of the congenital anomalies of the facial nerve: how to make sure your favorite surgeon does not hit CN7 during his procedure? Open
Poster: ECR 2016 / C-0659 / Imaging of the congenital anomalies of the facial nerve: how to make sure your favorite surgeon does not hit CN7 during his procedure? by: A. Venkatasamy 1, M. D. A. Cavalcanti1, S. Riehm1, F. Veillon2; …
View article: Fractures of the temporal bone: an easier way to read your CT
Fractures of the temporal bone: an easier way to read your CT Open
Poster: ECR 2016 / B-0720 / Fractures of the temporal bone: an easier way to read your CT by: A. Venkatasamy 1, F. Veillon1, B. Rock1, S. Riehm1, P. Meriot2, P. Baur1, A. Charpiot1; 1Strasbourg/FR, 2Brest/FR
View article: Imaging of the complications of middle ear surgery : how do I keep my favorite surgeon away from jail?
Imaging of the complications of middle ear surgery : how do I keep my favorite surgeon away from jail? Open
Poster: ECR 2016 / C-0658 / Imaging of the complications of middle ear surgery : how do I keep my favorite surgeon away from jail? by: A. Venkatasamy 1, M. D. A. Cavalcanti1, M. Eliezer2, F. Veillon3; 1Strasbourg/FR, 2paris/FR, 3St…