Aiping Wang
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View article: Identification of a Linear B-Cell Epitope in the African Swine Fever Virus pE248R Protein Targeted by Monoclonal Antibodies
Identification of a Linear B-Cell Epitope in the African Swine Fever Virus pE248R Protein Targeted by Monoclonal Antibodies Open
African swine fever virus (ASFV) is the only member of the family Asfarviridae and can cause African swine fever, a disease with a consistently high mortality rate. The pE248R protein, a myristoylated integral membrane protein of ASFV, is …
View article: Synergistic catalysis: Ionic liquid-modified trinuclear ruthenium clusters enhanced CO2-integrated methoxycarbonylation of ethylene
Synergistic catalysis: Ionic liquid-modified trinuclear ruthenium clusters enhanced CO2-integrated methoxycarbonylation of ethylene Open
View article: Pathogen-anchoring nano electrosensitizer serves as electro-driven antibiotic adjuvant to revitalize carbapenems activity against NDMs-producing CRE
Pathogen-anchoring nano electrosensitizer serves as electro-driven antibiotic adjuvant to revitalize carbapenems activity against NDMs-producing CRE Open
View article: Design and development of a bispecific antibody targeting BAFF and IL-17 for systemic lupus erythematosus treatment
Design and development of a bispecific antibody targeting BAFF and IL-17 for systemic lupus erythematosus treatment Open
The bsscFv exhibited potent neutralizing activity in vitro and therapeutic efficacy in vivo, suggesting it as a promising bispecific therapeutic agent for the treatment of SLE. Further studies are warranted to explore its clinical potentia…
View article: Identification of linear B-cell epitopes on the gE envelope protein of varicella-zoster virus
Identification of linear B-cell epitopes on the gE envelope protein of varicella-zoster virus Open
Varicella-zoster virus (VZV) is a highly infectious DNA virus with an envelope. It is the pathogen causing varicella and herpes zoster. The glycoprotein E (gE) envelope protein, a primary target for VZV diagnostic reagents and vaccines, is…
View article: Development of performance-matched oxaziclomefone nanosuspension based on the hydrophobic surface characteristics of barnyardgrass for unmanned aerial vehicle sprayer to improve herbicidal activity in direct-seeded rice fields
Development of performance-matched oxaziclomefone nanosuspension based on the hydrophobic surface characteristics of barnyardgrass for unmanned aerial vehicle sprayer to improve herbicidal activity in direct-seeded rice fields Open
View article: RDYH58 functional exosomes targeting myofibroblasts loaded with siFKBP10 for inhibition of collagen biosynthesis and secretion of IPF
RDYH58 functional exosomes targeting myofibroblasts loaded with siFKBP10 for inhibition of collagen biosynthesis and secretion of IPF Open
View article: Annular Lesions Mimicking Mpox in a Patient With HIV
Annular Lesions Mimicking Mpox in a Patient With HIV Open
Syphilis, a chronic bacterial infection caused by Treponema pallidum , is now reemerging as a global public health problem, particularly among men who have homosexual relationships. Because syphilis could mimic various diseases and could c…
View article: Palmitoylation enhances the stability of porcine epidemic diarrhea virus spike protein by antagonizing its degradation via chaperone-mediated autophagy to facilitate viral proliferation
Palmitoylation enhances the stability of porcine epidemic diarrhea virus spike protein by antagonizing its degradation via chaperone-mediated autophagy to facilitate viral proliferation Open
Porcine epidemic diarrhea (PED) is a highly pathogenic and infectious intestinal disease caused by the PED virus (PEDV) and has inflicted substantial economic losses on the global swine industry. Therefore, it is imperative to explore appr…
View article: NCAPH promotes glucose metabolism reprogramming and cell stemness in ovarian cancer cells through the MEK/ERK/PD-L1 pathway
NCAPH promotes glucose metabolism reprogramming and cell stemness in ovarian cancer cells through the MEK/ERK/PD-L1 pathway Open
Not applicable.
View article: Self‐Activatable Multi‐Module Nanoelectrode Triggering Electro‐Driven Pyroptosis in Cancer Cells Boost Anti‐Tumor Immunity
Self‐Activatable Multi‐Module Nanoelectrode Triggering Electro‐Driven Pyroptosis in Cancer Cells Boost Anti‐Tumor Immunity Open
Pyroptosis holds significant promise in facilitating tumor immunotherapy, but its efficiency is hindered by the indiscriminate pyroptotic killing of cells within cancer tissues and inadequate expression of gasdermin in cancer cells. Herein…
View article: MoSViT: a lightweight vision transformer framework for efficient disease detection via precision attention mechanism
MoSViT: a lightweight vision transformer framework for efficient disease detection via precision attention mechanism Open
Maize, a globally essential staple crop, suffers significant yield losses due to diseases. Traditional diagnostic methods are often inefficient and subjective, posing challenges for timely and accurate pest management. This study introduce…
View article: Engineering Lipid Nanoparticles to Enhance Intracellular Delivery of Transforming Growth Factor-Beta siRNA (siTGF-β1) via Inhalation for Improving Pulmonary Fibrosis Post-Bleomycin Challenge
Engineering Lipid Nanoparticles to Enhance Intracellular Delivery of Transforming Growth Factor-Beta siRNA (siTGF-β1) via Inhalation for Improving Pulmonary Fibrosis Post-Bleomycin Challenge Open
Background/Objectives: Transforming Growth Factor-beta (TGFβ1) plays a core role in the process of pulmonary fibrosis (PF). The progression of pulmonary fibrosis can be alleviated by siRNA-based inhibiting TGF-β1. However, the limitations …
View article: 一种基于 Ag-GO-Nf 纳米复合材料的高灵敏度电化学免疫传感器，用于培氟沙星的检测
一种基于 Ag-GO-Nf 纳米复合材料的高灵敏度电化学免疫传感器，用于培氟沙星的检测 Open
View article: Quantum Dot-Based Fluorescence-Linked Immunosorbent Assay for the Detection of Medroxyprogesterone Acetate in Milk
Quantum Dot-Based Fluorescence-Linked Immunosorbent Assay for the Detection of Medroxyprogesterone Acetate in Milk Open
View article: Quantitative fluorescent detection of tetracycline in animal-derived foods using quantum dots
Quantitative fluorescent detection of tetracycline in animal-derived foods using quantum dots Open
Tetracycline (Tc) antibiotics, a class of synthetically produced broad-spectrum antimicrobial drugs, have been widely used in animal husbandry, leading to their widespread presence in animal-derived foods. However, misuse, overuse, and non…
View article: NCAPH promotes glucose metabolism reprogramming and cell stemness in ovarian cancer cells through the MEK/ERK/PD-L1 pathway
NCAPH promotes glucose metabolism reprogramming and cell stemness in ovarian cancer cells through the MEK/ERK/PD-L1 pathway Open
Backgrounds: Ovarian cancer is a prevalent malignant tumors affecting the female reproductive organs with the characteristic of high heterogeneity. Non-structural maintenance of chromosomes condensin I complex subunit H (NCAPH) has been im…
View article: Symptom network connectivity and interaction among people with HIV in China: secondary analysis based on a cross-sectional survey
Symptom network connectivity and interaction among people with HIV in China: secondary analysis based on a cross-sectional survey Open
Early identification and assessment of the central or bridge symptoms should be emphasized in clinical practice. According to the findings from network analysis, healthcare providers should proactively explore intervention strategies or bu…
View article: A deep learning method that identifies cellular heterogeneity using nanoscale nuclear features
A deep learning method that identifies cellular heterogeneity using nanoscale nuclear features Open
View article: Validation and Refinement of the Self-Regulatory HIV/AIDS Symptom Management Model Among People With HIV in China Using Path Analysis: A Secondary Data Analysis
Validation and Refinement of the Self-Regulatory HIV/AIDS Symptom Management Model Among People With HIV in China Using Path Analysis: A Secondary Data Analysis Open
This study explored the path affecting the quality of life (QOL) of people with HIV in China and clarified the applicability and interpretability of the Self-Regulatory HIV/AIDS Symptom Management Model. We conducted a cross-sectional surv…
View article: Pulmonary artery smooth muscle cell pyroptosis promotes the proliferation of PASMCs by paracrine IL‑1β and IL‑18 in monocrotaline‑induced pulmonary arterial hypertensive rats
Pulmonary artery smooth muscle cell pyroptosis promotes the proliferation of PASMCs by paracrine IL‑1β and IL‑18 in monocrotaline‑induced pulmonary arterial hypertensive rats Open
Pulmonary arterial hypertension (PAH) is a common vascular disease, and pulmonary vascular remodeling is a pivotal pathophysiological mechanism of PAH. Major pathological changes of pulmonary arterial remodeling, including proliferation, h…
View article: Evaluating the application of a new patented fluorochrome, Fluorescent Brightener 85, for detecting cultured fungi and superficial clinical specimens of fungal infectious disease.
Evaluating the application of a new patented fluorochrome, Fluorescent Brightener 85, for detecting cultured fungi and superficial clinical specimens of fungal infectious disease. Open
Background: The fluorescent staining method with Calcofluor White (CFW) has been popularly used for the detection of fungi in clinical settings in recent years. However, seldom have new fluorochromes been invented to detect fungi. Purpose:…
View article: Nebulized milk exosomes loaded with siTGF-β1 ameliorate pulmonary fibrosis by inhibiting EMT pathway and enhancing collagen permeability
Nebulized milk exosomes loaded with siTGF-β1 ameliorate pulmonary fibrosis by inhibiting EMT pathway and enhancing collagen permeability Open
Pulmonary Fibrosis (PF) is a fatal disease in the interstitial lung associated with high mortality, morbidity, and poor prognosis. Transforming growth factor-β1 (TGF-β1) is a fibroblast-activating protein that promotes fibrous diseases. He…
View article: Lipid-lowering effect and oral transport characteristics study of curculigoside
Lipid-lowering effect and oral transport characteristics study of curculigoside Open
Introduction The incidence of metabolic disorders during pregnancy is increasing year by year, with diseases including hypertension and hyperlipidemia. Statins are the primary drugs for treating hyperlipidemia or atherosclerosis, yet some …
View article: Development and application of a high-sensitivity immunochromatographic test strip for detecting pseudorabies virus
Development and application of a high-sensitivity immunochromatographic test strip for detecting pseudorabies virus Open
Introduction Pseudorabies (PR) is a multi-animal comorbid disease caused by pseudorabies virus (PRV), which are naturally found in pigs. At the end of 2011, the emergence of PRV variant strains in many provinces in China had caused huge ec…
View article: Insight into complexation of Pd-catalyst for methoxycarbonylation of ethene
Insight into complexation of Pd-catalyst for methoxycarbonylation of ethene Open
The complexation of palladium with bidentate phosphine ligand has significant effects on the activity of the catalyst for methoxycarbonylation of ethene. Herein, the influence of the ratio of components, kind and sequence of additives, com…
View article: Nanovaccine Confers Dual Protection Against Influenza a Virus and Porcine Circovirus Type 2 [Retraction]
Nanovaccine Confers Dual Protection Against Influenza a Virus and Porcine Circovirus Type 2 [Retraction] Open
[This retracts the article DOI: 10.2147/IJN.S218057.].
View article: On-site detection and differentiation of African swine fever virus variants using an orthogonal CRISPR-Cas12b/Cas13a-based assay
On-site detection and differentiation of African swine fever virus variants using an orthogonal CRISPR-Cas12b/Cas13a-based assay Open
The African swine fever virus (ASFV) and its variants have induced substantial economic losses in China, prompting a critical need for efficient detection methods. Several PCR-based methods have been developed to discriminate between wild-…
View article: A universal design of restructured dimer antigens: Development of a superior vaccine against the paramyxovirus in transgenic rice
A universal design of restructured dimer antigens: Development of a superior vaccine against the paramyxovirus in transgenic rice Open
The development of vaccines, which induce effective immune responses while ensuring safety and affordability, remains a substantial challenge. In this study, we proposed a vaccine model of a restructured “head-to-tail” dimer to efficiently…
View article: Identification of a novel B-cell epitope of the African swine fever virus p34 protein and development of an indirect ELISA for the detection of serum antibodies
Identification of a novel B-cell epitope of the African swine fever virus p34 protein and development of an indirect ELISA for the detection of serum antibodies Open
African swine fever (ASF) is a viral disease caused by the African swine fever virus that can be highly transmitted and lethal in domestic pigs. In the absence of a vaccine, effective diagnosis is critical for minimizing the virus’s spread…