Axel J. Schmidt
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View article: Behavior change and infection induced immunity led to the decline of the 2022 Mpox outbreak in Berlin
Behavior change and infection induced immunity led to the decline of the 2022 Mpox outbreak in Berlin Open
Background Mpox denotes a viral zoonosis caused by the Orthopoxvirus monkeypox (MPXV), which is endemic in West and Central Africa. In spring 2022, notable outbreaks of MPXV clade IIb were recorded in several high-income countries, predomi…
View article: Modelling the health and cost implications of expanded access to HIV, HCV and sexually transmitted infection testing in Switzerland
Modelling the health and cost implications of expanded access to HIV, HCV and sexually transmitted infection testing in Switzerland Open
BACKGROUND: This study was conducted as part of the Swiss National Programme to Stop HIV, Hepatitis B Virus, Hepatitis C Virus and Sexually Transmitted Infections (NAPS), which aims to reduce the spread of sexually transmitted infections i…
View article: European Men-Who-Have-Sex-With-Men and Trans People Internet Survey (EMIS-2024): Design and Methods
European Men-Who-Have-Sex-With-Men and Trans People Internet Survey (EMIS-2024): Design and Methods Open
Men who have sex with men (MSM), as well as transgender and non-binary individuals, continue to face a disproportionate burden of stigma, mental health challenges, HIV, and other sexually transmitted infections. To address their needs, pub…
View article: German‐Austrian guideline on screening for anal dysplasia and anal carcinoma in people living with HIV
German‐Austrian guideline on screening for anal dysplasia and anal carcinoma in people living with HIV Open
Summary People with HIV are up to 100 times more likely to develop anal carcinoma compared to the general population. Diagnosing and treating precursor lesions, specifically high‐grade anal dysplasia, can significantly reduce the risk of d…
View article: A Prospective Case Series on the Hospital Management of Simple Febrile Seizures in Children
A Prospective Case Series on the Hospital Management of Simple Febrile Seizures in Children Open
Aim: Simple febrile seizures (SFS) are common neurological events in children aged 6 months to 5 years, presenting as brief, generalized seizures associated with fever, without CNS infection or metabolic abnormalities.To evaluate the clini…
View article: RETRACTED: What led to the sharp decline in mpox diagnoses in Berlin after the outbreak peaked in July 2022?
RETRACTED: What led to the sharp decline in mpox diagnoses in Berlin after the outbreak peaked in July 2022? Open
The authors have requested that this preprint be removed from Research Square.
View article: Indicative mapping of peat and other hydromorphic organic soils across Austria with legacy data
Indicative mapping of peat and other hydromorphic organic soils across Austria with legacy data Open
Understanding the spatial distribution of peat soils and other hydromorphic organic soils is essential for terrestrial carbon storage, biodiversity, and sustainable land management. In addition to these overarching purposes, there is now a…
View article: Impact of increased diagnosis of early HIV infection and immediate antiretroviral treatment initiation on HIV transmission among men who have sex with men in the Netherlands
Impact of increased diagnosis of early HIV infection and immediate antiretroviral treatment initiation on HIV transmission among men who have sex with men in the Netherlands Open
The number of new HIV infections among men who have sex with men (MSM) in the Netherlands has been decreasing, but additional efforts are required to bring it further down. This study aims to assess the impact of increased diagnosis of ear…
View article: German evidence‐ and consensus‐based guideline on the management of penile urethritis
German evidence‐ and consensus‐based guideline on the management of penile urethritis Open
Summary Urethritis is a common condition predominantly caused by sexually transmitted pathogens such as Chlamydia trachomatis , Neisseria gonorrhoeae , and Mycoplasma genitalium . It is not possible to differentiate with certainty between …
View article: Viral hepatitis knowledge and vaccination awareness among men who have sex with men (MSM) in 43 countries of the WHO European Region: results from the European MSM Internet Survey, EMIS-2017
Viral hepatitis knowledge and vaccination awareness among men who have sex with men (MSM) in 43 countries of the WHO European Region: results from the European MSM Internet Survey, EMIS-2017 Open
Background Recent hepatitis A virus outbreaks in Europe affecting men who have sex with men (MSM) and ongoing hepatitis B virus transmission among MSM underscore the ongoing need for viral hepatitis prevention in this population. Aim To de…
View article: Self-reported hepatitis A and B vaccination coverage among men who have sex with men (MSM), associated factors and vaccination recommendations in 43 countries of the WHO European Region: results from the European MSM Internet Survey, EMIS-2017
Self-reported hepatitis A and B vaccination coverage among men who have sex with men (MSM), associated factors and vaccination recommendations in 43 countries of the WHO European Region: results from the European MSM Internet Survey, EMIS-2017 Open
Background Hepatitis A and B vaccinations are recommended for men who have sex with men (MSM), given their increased risk of infection. However, data on vaccination programmes are scarce. Aim To use information on vaccination recommendatio…
View article: HIV Testing and Treatment among HIV-Positive Men who have Sex with Men (MSM) Living in Russia: Data from Two Waves of the European MSM Internet Survey
HIV Testing and Treatment among HIV-Positive Men who have Sex with Men (MSM) Living in Russia: Data from Two Waves of the European MSM Internet Survey Open
We examined changes in HIV testing and medical care among men who have sex with men (MSM) in Russia. Data come from the 2010 and 2017 waves of the European MSM Internet Survey. From 2010 to 2017 there was an increase in the proportion who …
View article: Reemergence of Clade IIb–Associated Mpox, Germany, July–December 2023
Reemergence of Clade IIb–Associated Mpox, Germany, July–December 2023 Open
In July 2023, clade IIb-associated mpox reemerged in Germany at low levels, mainly affecting men who have sex with men. We report a representative case and phylogeny of available genome sequences. Our findings underscore the need for stand…
View article: Clinically inapparent mpox virus (MPXV) infections among clients of three anonymous Community Based Voluntary Counselling and Testing centres in Berlin, Germany, 2022–2023
Clinically inapparent mpox virus (MPXV) infections among clients of three anonymous Community Based Voluntary Counselling and Testing centres in Berlin, Germany, 2022–2023 Open
Introduction Since the mpox outbreak in 2022, it was unclear if and how often infections with mpox virus (MPXV) were clinically inapparent, i.e. not presenting to clinical care with mpox symptoms. Moreover, it was hypothesized that MPXV ci…
View article: Recently acquired <scp>HCV</scp> infection in men who have sex with men in Germany in the direct‐acting antivirals era and during the <scp>COVID</scp>‐19 pandemic
Recently acquired <span>HCV</span> infection in men who have sex with men in Germany in the direct‐acting antivirals era and during the <span>COVID</span>‐19 pandemic Open
Introduction Direct‐acting antivirals (DAAs) are key to eliminating hepatitis C virus (HCV). In men who have sex with men (MSM) with HIV co‐infection, recently acquired HCV infection is common. Sexual practices and reinfection rates may ha…
View article: Still trouble with bleeding: Risk factors for <scp>HCV</scp> transmission in men who have sex with men and behavioural trajectories from 2019 to 2021
Still trouble with bleeding: Risk factors for <span>HCV</span> transmission in men who have sex with men and behavioural trajectories from 2019 to 2021 Open
Objectives To identify sexual/sex‐associated risk factors for hepatitis C transmission among men who have sex with men (MSM) and visualise behavioural trajectories from 2019 to 2021. Methods We linked a behavioural survey to a hepatitis C …
View article: Impact of increased diagnosis for early HIV infection and immediate antiretroviral treatment initiation on HIV transmission among men who have sex with men in the Netherlands
Impact of increased diagnosis for early HIV infection and immediate antiretroviral treatment initiation on HIV transmission among men who have sex with men in the Netherlands Open
The number of new HIV infections among men who have sex with men (MSM) in the Netherlands has been decreasing, but additional efforts are required to bring it further down. This study aims to assess the impact of increased diagnosis for ea…
View article: Response to “On the risk of using raw regional data on new HIV infections in France” by Tassi et al.
Response to “On the risk of using raw regional data on new HIV infections in France” by Tassi et al. Open
Our colleagues Tassi et al. submitted a Letter to the Editor regarding our recent paper on the spatio-temporal changes in pre-exposure prophylaxis (PrEP) uptake among men who have sex with men (MSM) in France [1]. We appreciate their inter…
View article: Position statement of the German STI Society on the prophylactic use of doxycycline to prevent STIs (Doxy‐PEP, Doxy‐PrEP)
Position statement of the German STI Society on the prophylactic use of doxycycline to prevent STIs (Doxy‐PEP, Doxy‐PrEP) Open
Summary Over the past two decades, there has been a rise in the incidence of syphilis, particularly among men who have sex with men (MSM). This has sparked interest in studying the prophylactic use of doxycycline to prevent syphilis and ot…
View article: Impact of directly acting-antivirals and behavior change due to the COVID 19 pandemic on HCV micro-elimination in MSM in Germany
Impact of directly acting-antivirals and behavior change due to the COVID 19 pandemic on HCV micro-elimination in MSM in Germany Open
Introduction Directly-acting antivirals (DAA) are the cornerstone to reach HCV elimination. In men who have sex with men (MSM) with HIV coinfection, recently acquired HCV infection (RAHCV) is common. Sexual practices and reinfection rates …
View article: When awareness is not a barrier to PrEP uptake among men who have sex with men who are eligible for PrEP in France
When awareness is not a barrier to PrEP uptake among men who have sex with men who are eligible for PrEP in France Open
Despite PrEP being available and free of charge in France, a gap remains between the estimated number of men who have sex with men (MSM) with high-risk exposure to HIV and the number of MSM PrEP users. The objective of this study is to ide…
View article: Reply to ‘Assessing the hepatitis C epidemiology in Switzerland: It’s not that trivial’
Reply to ‘Assessing the hepatitis C epidemiology in Switzerland: It’s not that trivial’ Open
We thank Sarah Blach et al. for bringing attention to our update paper on the prevalence of HCV infections in Switzerland. Blach et al. aim to challenge our estimate of 5900–9200 persons living in Switzerland with chronic hepatitis C in 20…
View article: Incidence of sexually transmitted infections and association with behavioural factors: Time‐to‐event analysis of a large pre‐exposure prophylaxis (<scp>PrEP</scp>) cohort
Incidence of sexually transmitted infections and association with behavioural factors: Time‐to‐event analysis of a large pre‐exposure prophylaxis (<span>PrEP</span>) cohort Open
Objectives Our objective was to obtain long‐term data on the incidence of sexually transmitted infections (STIs) and their association with behavioural factors after widespread pre‐exposure prophylaxis (PrEP) implementation. Methods This w…
View article: Chronic hepatitis C virus infections in Switzerland in 2020: Lower than expected and suggesting achievement of <scp>WHO</scp> elimination targets
Chronic hepatitis C virus infections in Switzerland in 2020: Lower than expected and suggesting achievement of <span>WHO</span> elimination targets Open
In this multi‐method study, we investigated the prevalence of chronic infections with the hepatitis C virus (HCV) in Switzerland in 2020, and assessed Switzerland's progress in eliminating HCV as a public health problem by 2030 with regard…
View article: Comparison of the burden of self-reported bacterial sexually transmitted infections among men having sex with men across 68 countries on four continents
Comparison of the burden of self-reported bacterial sexually transmitted infections among men having sex with men across 68 countries on four continents Open
Background Men who have sex with men (MSM) are in general more vulnerable to sexually transmitted infections (STIs) than the heterosexual men population. However, surveillance data on STI diagnoses lack comparability across countries due t…
View article: Spatio‐temporal changes in pre‐exposure prophylaxis uptake among MSM in mainland France between 2016 and 2021: a Bayesian small area approach with MSM population estimation
Spatio‐temporal changes in pre‐exposure prophylaxis uptake among MSM in mainland France between 2016 and 2021: a Bayesian small area approach with MSM population estimation Open
Introduction In France, oral pre‐exposure prophylaxis (PrEP) for HIV prevention has been publicly available since 2016, mainly targeting at men who have sex with men (MSM). Reliable and robust estimations of the actual PrEP uptake among MS…
View article: Association of internalised homonegativity with partner notification after diagnosis of syphilis or gonorrhoea among men having sex with men in 49 countries across four continents
Association of internalised homonegativity with partner notification after diagnosis of syphilis or gonorrhoea among men having sex with men in 49 countries across four continents Open
Background Partner notification (PN) after a sexually transmitted infection (STI) diagnosis is being promoted as a means to interrupt transmission chains. We investigated whether Internalised Homonegativity (IH) is associated with PN among…